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The map label for this gene is ycbL [H]

Identifier: 113969777

GI number: 113969777

Start: 1679156

End: 1679800

Strand: Direct

Name: ycbL [H]

Synonym: Shewmr4_1435

Alternate gene names: 113969777

Gene position: 1679156-1679800 (Clockwise)

Preceding gene: 113969775

Following gene: 113969778

Centisome position: 35.68

GC content: 48.68

Gene sequence:

>645_bases
ATGAAGTATCAAATTATTCCTGTGACACCTTTCCAACAGAATTGCAGCTTGATTTGGTGTGAAAAAACTAAGCGTGCCGC
GGTTGTCGATCCGGGAGGGAATGTCGACCGTATTCTAGGTGAAATGGACAAATTGGGACTGACCCTCGAAAAAGTGCTGC
TGACCCACGGCCATATCGACCATGTGGGTGGCGCTAAACTCTTGGCGCAGCAAACGAATGTGCCGATCATTGGCCCCCAT
GAGGCCGATAAATTTTGGATTGATAATCTACCTAAACAAAGCCAAAACTTTGGTTTTCCCCACTGTGAGGCCTTTGAACC
CGACCAATATCTGCAGGATGGTGATGTCGTTACCGTAGGTGAACAAAACTTAAGTGTGCTGCATTGCCCTGGGCATACAC
CGGGTCACGTAGCATTTTACTCCGCTGAGGCCAAGCTTGCGTGGGTGGGCGATATCCTGTTTAGAAGCTCGATTGGCCGT
ACCGATTTTCCCCAATCAAATCATCAAAGTTTGATCCATTCCATTACCACCAAGCTCTGGCCTTTAGGGGCCGACGTGGA
ATTTATTCCCGGCCACGGACCTATGTCGACCTTTGGTGAAGAGCGTGAACATAACCCTTTCGTGGCGGATCAATTACTGC
TTTAA

Upstream 100 bases:

>100_bases
GATTAGCCTTTGGTTGAGATCAATTTTTATTGTAAAAAATTGAGCCATCATAAGCCTCTTAGCGTAATCTATCGGCTATG
GATAACACGAGATTGAAGCT

Downstream 100 bases:

>100_bases
CTGCTCATCCATACGTTTGATCTATTTCAGTCATGTTTTGCGCAAGGTTAAAACTGGCACACTCGGTTTTCTGGTGTGCC
TGATTGAGATTGCAATAAAC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKYQIIPVTPFQQNCSLIWCEKTKRAAVVDPGGNVDRILGEMDKLGLTLEKVLLTHGHIDHVGGAKLLAQQTNVPIIGPH
EADKFWIDNLPKQSQNFGFPHCEAFEPDQYLQDGDVVTVGEQNLSVLHCPGHTPGHVAFYSAEAKLAWVGDILFRSSIGR
TDFPQSNHQSLIHSITTKLWPLGADVEFIPGHGPMSTFGEEREHNPFVADQLLL

Sequences:

>Translated_214_residues
MKYQIIPVTPFQQNCSLIWCEKTKRAAVVDPGGNVDRILGEMDKLGLTLEKVLLTHGHIDHVGGAKLLAQQTNVPIIGPH
EADKFWIDNLPKQSQNFGFPHCEAFEPDQYLQDGDVVTVGEQNLSVLHCPGHTPGHVAFYSAEAKLAWVGDILFRSSIGR
TDFPQSNHQSLIHSITTKLWPLGADVEFIPGHGPMSTFGEEREHNPFVADQLLL
>Mature_214_residues
MKYQIIPVTPFQQNCSLIWCEKTKRAAVVDPGGNVDRILGEMDKLGLTLEKVLLTHGHIDHVGGAKLLAQQTNVPIIGPH
EADKFWIDNLPKQSQNFGFPHCEAFEPDQYLQDGDVVTVGEQNLSVLHCPGHTPGHVAFYSAEAKLAWVGDILFRSSIGR
TDFPQSNHQSLIHSITTKLWPLGADVEFIPGHGPMSTFGEEREHNPFVADQLLL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=202, Percent_Identity=28.7128712871287, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=56.6037735849057, Blast_Score=268, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17538952, Length=195, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221330176, Length=190, Percent_Identity=24.7368421052632, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23721; Mature: 23721

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQIIPVTPFQQNCSLIWCEKTKRAAVVDPGGNVDRILGEMDKLGLTLEKVLLTHGHID
CCEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHCCCCC
HVGGAKLLAQQTNVPIIGPHEADKFWIDNLPKQSQNFGFPHCEAFEPDQYLQDGDVVTVG
CCCCHHHHHHHCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEC
EQNLSVLHCPGHTPGHVAFYSAEAKLAWVGDILFRSSIGRTDFPQSNHQSLIHSITTKLW
CCCCEEEECCCCCCCCEEEEECCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PLGADVEFIPGHGPMSTFGEEREHNPFVADQLLL
CCCCCEEEECCCCCCCHHCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MKYQIIPVTPFQQNCSLIWCEKTKRAAVVDPGGNVDRILGEMDKLGLTLEKVLLTHGHID
CCEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHCCCCC
HVGGAKLLAQQTNVPIIGPHEADKFWIDNLPKQSQNFGFPHCEAFEPDQYLQDGDVVTVG
CCCCHHHHHHHCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEC
EQNLSVLHCPGHTPGHVAFYSAEAKLAWVGDILFRSSIGRTDFPQSNHQSLIHSITTKLW
CCCCEEEECCCCCCCCEEEEECCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PLGADVEFIPGHGPMSTFGEEREHNPFVADQLLL
CCCCCEEEECCCCCCCHHCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]