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The map label for this gene is hlyB [H]

Identifier: 113969778

GI number: 113969778

Start: 1680133

End: 1681872

Strand: Direct

Name: hlyB [H]

Synonym: Shewmr4_1436

Alternate gene names: 113969778

Gene position: 1680133-1681872 (Clockwise)

Preceding gene: 113969777

Following gene: 113969779

Centisome position: 35.7

GC content: 48.33

Gene sequence:

>1740_bases
ATGAATACAAAAACAATGATGAGTGTTGTCTTTTCCACCATAGTCGTCAGTGCGTTGATTACGGCGGTGTTGAGTTTTAA
TGTCAAATCTAAGATTGAGCTTTTTAACAATGCAGCGAATATTCGCTATCAATCCTACCAAATTGCCGATGAATTAAGGC
AAAGCTCCGATGATTTAACGAGGCTCGCCCGAACCTATGCGGTGACTGGGGAGGATAAGTACGAAAAAATGTATATGGAT
ATTTTGGCGATACGTAATGGCGAAAAACCGAGGCCGGAAAAATATCACCAAATTTATTGGGATTTGGTACTCAGTTACGG
AGATAAACCTAAGCCAGACGGTGCCAGAGTCGCTATCAAAAGCCAAATGAAGGCCTTAGGGTTCTCCGACGAGGAATTCC
ATTATCTCGAGCAGGCTCAGCAAAATTCTGATGCCTTAGTCGCCCTTGAGGTCAAGGCGATGAATGCGGTCAAAGGGATT
TTTATGGATCCTAATACCCAAACCTACAGCATTAAAGGTGAACCAAACCTAGCGATGGCGCGAGAACTACTGCACAGCGA
GCAATACCATAGGGAAAAGGCCAAGATCATGCAGCCTATCGACGAGTTCTTTACTGCTTTGGATAAACGTACCGAAGGCG
AAGTGAGCAATCGATTAGACTCCTTGAATATGGCACTCAATGGCTCACAGTTTGTGTTGTTTCTGGTGATTTTGGTCGCC
GTTGGTGGCTTTGTGATTGTGAAGAGTCGCATCGTAACGCCGATAGTGCAAACCTGCCGTGAACTACTCGATATTCAACG
TTCTAAAAATCTGGCGCGGCGGATCTCTGTCTCGGCGCAGGGTGAAATCGGTGAAATCGTCAATCAAATCAATTTGTTTA
TTTCTTCTCTCGCCAGCTCATTAGCGACAACGGATGGAATTGCCAAAGAAGTTGCCGATCTGGCGAAGCAGACCAAAGCC
TCCATTCAAGTGTCGCGTGAAAGCTCGAACCGCGTCGCGAAAGAGTTAGATGCCAGCGCGAGCGCGATGGAAGAGATGAC
TACCACCTTAGTGCATGTGAGTGAGAGCACCTCCAACGCCGAAATTCGTGCGGCAGAAAATGAAACCCATGTGGGCGTTG
GCCAAGATACAGTATCTGAGGCGCTCAATGCCATGGCCGTGCTTGAGAGCGAATTTACGACTACCCAAGATTCGATGCAG
CATTTAGTGAACGAGAGCACCCAAGTGAGTAATGTGCTGAGCGTCATTAAGGCAATTGCCGAACAAACCAACCTACTGGC
GCTCAATGCGGCGATTGAAGCTGCGAGGGCAGGCGAACAGGGCCGAGGCTTTGCTGTGGTGGCCGATGAAGTGCGTTCAC
TCGCCCAGCGGACACAGGATTCCACTAAGGAAATCGACGATATTGTTGCCAGTTTGCAGAATCGAACCAATCAGGTGGGC
AGCTCTGTCACCCAGGCGGCGAGTTTAATGCAGAAAGCCTCAGGTGAATTACAGCGTATCGTGACTGTCTTCGATGATAT
TCGCCATAGCACGGCGGCCATCCATGGGATCAATACGCAAGTCGCCGCCTCAACCGAGGAGCAATCTTTGGTTTCTAAGG
ATATTGCCACTAGTCTTGTGGTGATCCGCGATAACTCCCGCGAGGTATCGCAAATTATCGAGCAAATTGAGTCCACCTCC
ATCAGTTTGGATAATCAATCCCAAGCGCTACGCACCAAAGCGGGGGAATATCAGTTTTAA

Upstream 100 bases:

>100_bases
ACTATTTATATTGCCTAATTTTATTCTGAAATTTACTTTTTTGTTACATATTCCCAGCTAGACTTAAATCAGCGGTTGTA
TTTGTCTATTGGGGTTTACT

Downstream 100 bases:

>100_bases
TACTTAATCTCGGGGTCCTGCAACGGGACTGGCATAGATGACAGGGATGTCAGACTGTTCCGCTTAATCCAATCAACCTT
TCCGCTTCTTTTCCCTTTTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MNTKTMMSVVFSTIVVSALITAVLSFNVKSKIELFNNAANIRYQSYQIADELRQSSDDLTRLARTYAVTGEDKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKSQMKALGFSDEEFHYLEQAQQNSDALVALEVKAMNAVKGI
FMDPNTQTYSIKGEPNLAMARELLHSEQYHREKAKIMQPIDEFFTALDKRTEGEVSNRLDSLNMALNGSQFVLFLVILVA
VGGFVIVKSRIVTPIVQTCRELLDIQRSKNLARRISVSAQGEIGEIVNQINLFISSLASSLATTDGIAKEVADLAKQTKA
SIQVSRESSNRVAKELDASASAMEEMTTTLVHVSESTSNAEIRAAENETHVGVGQDTVSEALNAMAVLESEFTTTQDSMQ
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQNRTNQVG
SSVTQAASLMQKASGELQRIVTVFDDIRHSTAAIHGINTQVAASTEEQSLVSKDIATSLVVIRDNSREVSQIIEQIESTS
ISLDNQSQALRTKAGEYQF

Sequences:

>Translated_579_residues
MNTKTMMSVVFSTIVVSALITAVLSFNVKSKIELFNNAANIRYQSYQIADELRQSSDDLTRLARTYAVTGEDKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKSQMKALGFSDEEFHYLEQAQQNSDALVALEVKAMNAVKGI
FMDPNTQTYSIKGEPNLAMARELLHSEQYHREKAKIMQPIDEFFTALDKRTEGEVSNRLDSLNMALNGSQFVLFLVILVA
VGGFVIVKSRIVTPIVQTCRELLDIQRSKNLARRISVSAQGEIGEIVNQINLFISSLASSLATTDGIAKEVADLAKQTKA
SIQVSRESSNRVAKELDASASAMEEMTTTLVHVSESTSNAEIRAAENETHVGVGQDTVSEALNAMAVLESEFTTTQDSMQ
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQNRTNQVG
SSVTQAASLMQKASGELQRIVTVFDDIRHSTAAIHGINTQVAASTEEQSLVSKDIATSLVVIRDNSREVSQIIEQIESTS
ISLDNQSQALRTKAGEYQF
>Mature_579_residues
MNTKTMMSVVFSTIVVSALITAVLSFNVKSKIELFNNAANIRYQSYQIADELRQSSDDLTRLARTYAVTGEDKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKSQMKALGFSDEEFHYLEQAQQNSDALVALEVKAMNAVKGI
FMDPNTQTYSIKGEPNLAMARELLHSEQYHREKAKIMQPIDEFFTALDKRTEGEVSNRLDSLNMALNGSQFVLFLVILVA
VGGFVIVKSRIVTPIVQTCRELLDIQRSKNLARRISVSAQGEIGEIVNQINLFISSLASSLATTDGIAKEVADLAKQTKA
SIQVSRESSNRVAKELDASASAMEEMTTTLVHVSESTSNAEIRAAENETHVGVGQDTVSEALNAMAVLESEFTTTQDSMQ
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQNRTNQVG
SSVTQAASLMQKASGELQRIVTVFDDIRHSTAAIHGINTQVAASTEEQSLVSKDIATSLVVIRDNSREVSQIIEQIESTS
ISLDNQSQALRTKAGEYQF

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=415, Percent_Identity=25.0602409638554, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788194, Length=364, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI2367378, Length=333, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788195, Length=294, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789453, Length=295, Percent_Identity=27.4576271186441, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63603; Mature: 63603

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKTMMSVVFSTIVVSALITAVLSFNVKSKIELFNNAANIRYQSYQIADELRQSSDDLT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHH
RLARTYAVTGEDKYEKMYMDILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHH
SQMKALGFSDEEFHYLEQAQQNSDALVALEVKAMNAVKGIFMDPNTQTYSIKGEPNLAMA
HHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCEECCCCEEEEECCCCCHHHH
RELLHSEQYHREKAKIMQPIDEFFTALDKRTEGEVSNRLDSLNMALNGSQFVLFLVILVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VGGFVIVKSRIVTPIVQTCRELLDIQRSKNLARRISVSAQGEIGEIVNQINLFISSLASS
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LATTDGIAKEVADLAKQTKASIQVSRESSNRVAKELDASASAMEEMTTTLVHVSESTSNA
HHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
EIRAAENETHVGVGQDTVSEALNAMAVLESEFTTTQDSMQHLVNESTQVSNVLSVIKAIA
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQNRTNQVG
HHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
SSVTQAASLMQKASGELQRIVTVFDDIRHSTAAIHGINTQVAASTEEQSLVSKDIATSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHEEE
VIRDNSREVSQIIEQIESTSISLDNQSQALRTKAGEYQF
EEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTKTMMSVVFSTIVVSALITAVLSFNVKSKIELFNNAANIRYQSYQIADELRQSSDDLT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHH
RLARTYAVTGEDKYEKMYMDILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHH
SQMKALGFSDEEFHYLEQAQQNSDALVALEVKAMNAVKGIFMDPNTQTYSIKGEPNLAMA
HHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCEECCCCEEEEECCCCCHHHH
RELLHSEQYHREKAKIMQPIDEFFTALDKRTEGEVSNRLDSLNMALNGSQFVLFLVILVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VGGFVIVKSRIVTPIVQTCRELLDIQRSKNLARRISVSAQGEIGEIVNQINLFISSLASS
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LATTDGIAKEVADLAKQTKASIQVSRESSNRVAKELDASASAMEEMTTTLVHVSESTSNA
HHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
EIRAAENETHVGVGQDTVSEALNAMAVLESEFTTTQDSMQHLVNESTQVSNVLSVIKAIA
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQNRTNQVG
HHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
SSVTQAASLMQKASGELQRIVTVFDDIRHSTAAIHGINTQVAASTEEQSLVSKDIATSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHEEE
VIRDNSREVSQIIEQIESTSISLDNQSQALRTKAGEYQF
EEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]