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The map label for this gene is fba [H]

Identifier: 113969120

GI number: 113969120

Start: 903414

End: 904481

Strand: Direct

Name: fba [H]

Synonym: Shewmr4_0776

Alternate gene names: 113969120

Gene position: 903414-904481 (Clockwise)

Preceding gene: 113969119

Following gene: 113969121

Centisome position: 19.2

GC content: 49.44

Gene sequence:

>1068_bases
ATGGCGTTAATTTCCCTACGACAACTACTCGATCACGCGGCAGAGCATGGATACGGTGTGCCAGCGTTCAACGTAAACAA
CCTTGAGCAAATGCGCGCCATCATGCAGGCCGCAGAAGCTACAGACAGCCCAGTTATCGTGCAAGCCTCTGCGGGTGCAC
GTAAATATGCGCGTCCACAATTCTTAAAATACCTGATGACGGCTGCACTTGAGCAGTATCCTGATATCCCTGTCTGTATT
CACCAAGACCATGGTACCGATCCTGACATCTGTCAGCGTTCTATCCAATTAGGTATGTCATCAGTCATGATGGACGGTTC
ATTAATGGCCGACGGTAAAACCCCAGCTTCTTACGAGTACAACGTTGATGTGACTCGCAGAACTGTTGCATTCGCCCACG
CGTGTGGTGTGTCTGTAGAGGGGGAAATCGGTTGTTTAGGCAGCTTAGAAACCGGTACTGCCGGTGAAGAAGACGGTGTG
GGTGCAGAAGGCGTATTAAGCCACGACCAACTGCTGACCAGCCCAGAAGAAGCGGCTCGCTTCGTTGCTGATACCCATGT
TGACGCGCTGGCGATTGCGATTGGTACTAGCCACGGTGCATACAAGTTCAGCCGTAAACCAACGGGTGATGTACTGCGTA
TCGACCGCATCAAAGAAATCCATGCCCGCATTCCTAACACTCACTTAGTGATGCACGGTTCTTCTTCAGTGCCACAGGAA
TGGTTACAGATCATCAACCAATACGGTGGTCAAATTCCTGAAACTTACGGCGTGCCATTAGAAGAAATCGTTGAAGGTAT
CAAACACGGCGTGCGTAAAGTGAACATCGATACCGATTTGCGCTTAGCATCTACCGGTGCGGTACGTAAATACTTGGCCG
AACATCCAAGCGAGTTCGACCCTCGTAAGTTCCTGAAAGCCTCTATGGAAGCGATGGCAGACATCTGTACTGTTCGCTAC
GAAGCTTTCGGTTGTGCGGGTCAAGCTTCTAAGATTAAGCCATTGTCTTTACAAGCAATGTACAAAGCTTATCAGTCAGG
CGCATTAGATCCTAAGATCAATCTCTAA

Upstream 100 bases:

>100_bases
ACCTGTTCTTGAGTGATTGAGCATAAAAATCCATCCAAACGATAGCGACCTCGGTGACCTAACGTCGATGTGACAGTCAC
CCTATTATTGGAGTTAAAAA

Downstream 100 bases:

>100_bases
GCCTTAAATACTGCTCTAAAAAGCCCGCCAAAGTGCGGGCTTTTTTATGCAAAAAACCGTTGAATTTTCATTTTTTAATC
GTAAATGTTAGTATTGCCAT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMTAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGTAGEEDGV
GAEGVLSHDQLLTSPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKYLAEHPSEFDPRKFLKASMEAMADICTVRY
EAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINL

Sequences:

>Translated_355_residues
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMTAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGTAGEEDGV
GAEGVLSHDQLLTSPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKYLAEHPSEFDPRKFLKASMEAMADICTVRY
EAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINL
>Mature_354_residues
ALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMTAALEQYPDIPVCIH
QDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGTAGEEDGVG
AEGVLSHDQLLTSPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQEW
LQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKYLAEHPSEFDPRKFLKASMEAMADICTVRYE
AFGCAGQASKIKPLSLQAMYKAYQSGALDPKINL

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=330, Percent_Identity=34.2424242424242, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=33.7386018237082, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1788072, Length=288, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38511; Mature: 38380

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHH
FLKYLMTAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGTAGEEDGVGAEGVLSHDQLLTSPEEAAR
ECCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKYLAEHPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHHCCCCCC
PRKFLKASMEAMADICTVRYEAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ALISLRQLLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHCCHH
FLKYLMTAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGTAGEEDGVGAEGVLSHDQLLTSPEEAAR
ECCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLQIINQYGGQIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKYLAEHPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHHCCCCCC
PRKFLKASMEAMADICTVRYEAFGCAGQASKIKPLSLQAMYKAYQSGALDPKINL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]