Click here to switch to the map view.

The map label for this gene is pgk [H]

Identifier: 113969119

GI number: 113969119

Start: 902040

End: 903215

Strand: Direct

Name: pgk [H]

Synonym: Shewmr4_0775

Alternate gene names: 113969119

Gene position: 902040-903215 (Clockwise)

Preceding gene: 113969118

Following gene: 113969120

Centisome position: 19.17

GC content: 50.34

Gene sequence:

>1176_bases
ATGGCAATTATCAATATGTCAGATTTAGATCTCCAAGGTAAGCGAGTGCTTATTCGTGAAGATCTCAATGTGCCAGTCAG
CAACGGCGTCGTCACTAGTGATGCACGTCTTCGCGCCTCTCTTCCCACTATCGAATTAGCCCTTGCCAAAGGCGCAGCGG
TAATGGTGATGTCTCACTTAGGTCGTCCAACCGAAGGTGAATACAACAGCGAATTCTCCATGCAACCTGTGGTCGATTAC
TTGGCTAAAGCTCTGTCTTGCACCGTCCGTTTAGCGACCGACTATTTAGACGGCGTTGAAGTCGCGGTAGGCGAAGTGGT
TGTGTTTGAAAACGTTCGCTTTAACAAAGGCGAGAAGAAAAACGACGAAGCCCTGTCAAAGAAAATGGCAGCCTTATGTG
ATGTGTATGTGATGGATGCCTTCGGCACCGCTCACCGCGCAGAAGCGTCAACCAATGGTGTTGGCTTACACGCTCCTATC
GCCTGTGCTGGTCCATTATTAGCGCAAGAATTAGAAGCGTTAGGCAAAGCCTTAGACAACCCAGCGCGCCCATTAGTGGC
CATCGTTGGCGGTTCTAAAGTGTCGACTAAGCTGACCGTATTAGAAAGCTTATCTGGTATTGTGGACCAGTTAGTCGTTG
GCGGTGGTATCGCCAACACCTTTATCGCTGCGGCGGGCCACAATGTAGGTAAATCCTTATACGAAGCGGATTTAATTGAT
GAAGCTAAGCGCTTAGTGGCAAACGCCCAAAGCCGCGGTGGCGACATTCCTGTGCCTACCGATGTAGTTGTTGCGGGTGA
GTTTAGCCCTACAGCTGCTGCGACCTTAAAAGCGGTCAACGAAGTAGCCGATAGCGACATGATTTTCGACATCGGTCCCG
ACAGCGCCGAAGCCTTAGCGAAAATCATCGAGTCTGCTGGCACTATCGTATGGAACGGCCCTGTGGGCGTGTTCGAATTC
GACCAATTCGGTGAAGGCACTAAGCGTATCGCACAAGCTATCGCTGATTCTAAAGCCTTCTCTATCGCGGGCGGTGGTGA
CACCTTAGCGGCGGTCGACAAGTATGATATCGCCGATAAAGTCTCTTACATTTCTACTGGCGGTGGCGCTTTCCTTGAGT
TTTTAGAAGGTAAAGAGTTACCCGCTGTAGCTATGCTAAAACAACGCGGTGCCTAA

Upstream 100 bases:

>100_bases
GTGGCCAATTCGACGGGATGTCGAGTGCCGAGTAGCTATCTAAGCTAACCGATTGATGCAAAACCAGTTTGTTTTTTTGA
TTATAAAAGGAAGCGTTACC

Downstream 100 bases:

>100_bases
TATTGAGTTAGGTATTGCGCCATCGCGGCAGGGTGCTGCGATGGCACTAAAGCTTGATAAAAAATTATAAAAAACCGCTC
ATTCTCTTAAGAGCATTAAC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDY
LAKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPI
ACAGPLLAQELEALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLID
EAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVADSDMIFDIGPDSAEALAKIIESAGTIVWNGPVGVFEF
DQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLKQRGA

Sequences:

>Translated_391_residues
MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDY
LAKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPI
ACAGPLLAQELEALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLID
EAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVADSDMIFDIGPDSAEALAKIIESAGTIVWNGPVGVFEF
DQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLKQRGA
>Mature_390_residues
AIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDYL
AKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPIA
CAGPLLAQELEALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLIDE
AKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVADSDMIFDIGPDSAEALAKIIESAGTIVWNGPVGVFEFD
QFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLKQRGA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=411, Percent_Identity=39.1727493917275, Blast_Score=264, Evalue=9e-71,
Organism=Homo sapiens, GI4505763, Length=411, Percent_Identity=37.712895377129, Blast_Score=260, Evalue=2e-69,
Organism=Escherichia coli, GI1789294, Length=389, Percent_Identity=73.2647814910026, Blast_Score=567, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17508823, Length=409, Percent_Identity=42.5427872860636, Blast_Score=289, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6319857, Length=417, Percent_Identity=39.3285371702638, Blast_Score=272, Evalue=7e-74,
Organism=Drosophila melanogaster, GI17136394, Length=411, Percent_Identity=40.632603406326, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24581203, Length=411, Percent_Identity=37.956204379562, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 40695; Mature: 40564

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHL
CEEECCCCCCCCCCEEEEEECCCCCCCCCEEECCCHHEECCCEEEEHHHCCHHHHHHHHC
GRPTEGEYNSEFSMQPVVDYLAKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCCCCC
NDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPIACAGPLLAQELEALGKALDN
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLID
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
EAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVADSDMIFDIGPDSAEALA
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
KIIESAGTIVWNGPVGVFEFDQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADK
HHHHHCCCEEECCCCCEEECHHCCCHHHHHHHHHHCCCCEEEECCCCCEEHHCCHHHHHH
VSYISTGGGAFLEFLEGKELPAVAMLKQRGA
HHHHCCCCHHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHL
EEECCCCCCCCCCEEEEEECCCCCCCCCEEECCCHHEECCCEEEEHHHCCHHHHHHHHC
GRPTEGEYNSEFSMQPVVDYLAKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCCCCC
NDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPIACAGPLLAQELEALGKALDN
CHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLID
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
EAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVADSDMIFDIGPDSAEALA
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
KIIESAGTIVWNGPVGVFEFDQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADK
HHHHHCCCEEECCCCCEEECHHCCCHHHHHHHHHHCCCCEEEECCCCCEEHHCCHHHHHH
VSYISTGGGAFLEFLEGKELPAVAMLKQRGA
HHHHCCCCHHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA