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The map label for this gene is arsR [H]

Identifier: 113968876

GI number: 113968876

Start: 616319

End: 616663

Strand: Direct

Name: arsR [H]

Synonym: Shewmr4_0532

Alternate gene names: 113968876

Gene position: 616319-616663 (Clockwise)

Preceding gene: 113968874

Following gene: 113968877

Centisome position: 13.1

GC content: 49.57

Gene sequence:

>345_bases
ATGCAAGCCGTCGCCTTTTTTAAGGCCCTTGCCGATGAGACTCGGCTGAAATGTGTACTGCTCATCCAGCGAGAAGGGGA
GTTGTGCGTATGTGAATTAATGGCTGCGCTGTCGGAGATCCAGCCTAAGATCTCTCGGCATTTGGCGCAGTTAAAAAAAG
CAGGGATCTTAGTCGATAGGCGTCAGGGGCAATGGGTGTTTTATCAAATTAATCCTGAGCTTAGTGCTTGGTGTCAGCAA
GTATTAGCGCAAAGTTGTGAGGCTAATAGTCCGTTTTTAGCCGAGAGTATGCAGAACCTGTGCAGCATGGGTGCTCGTCC
CGAACGCGCTAAAGCCTGTTGTTGA

Upstream 100 bases:

>100_bases
TTATATACAGAGTTTATTTTGATGATAGCGACTAGATATATATGTTTTTTCATATATACTTTTATTCATATGTGTGTTGG
ATTTGTATAGGGGCTATTTC

Downstream 100 bases:

>100_bases
ATTGAAAAGAATGCATTTTGTGAGTCGAGGTTGTTATGGGGATCTTTGAACGTTATTTAAGTCTCTGGGTTGGCTTGAGT
ATTCTTGCAGGGGTCGCGCT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MQAVAFFKALADETRLKCVLLIQREGELCVCELMAALSEIQPKISRHLAQLKKAGILVDRRQGQWVFYQINPELSAWCQQ
VLAQSCEANSPFLAESMQNLCSMGARPERAKACC

Sequences:

>Translated_114_residues
MQAVAFFKALADETRLKCVLLIQREGELCVCELMAALSEIQPKISRHLAQLKKAGILVDRRQGQWVFYQINPELSAWCQQ
VLAQSCEANSPFLAESMQNLCSMGARPERAKACC
>Mature_114_residues
MQAVAFFKALADETRLKCVLLIQREGELCVCELMAALSEIQPKISRHLAQLKKAGILVDRRQGQWVFYQINPELSAWCQQ
VLAQSCEANSPFLAESMQNLCSMGARPERAKACC

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=82, Percent_Identity=52.4390243902439, Blast_Score=99, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12774; Mature: 12774

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
10.5 %Cys+Met (Translated Protein)
7.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
10.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVAFFKALADETRLKCVLLIQREGELCVCELMAALSEIQPKISRHLAQLKKAGILVDR
CHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
RQGQWVFYQINPELSAWCQQVLAQSCEANSPFLAESMQNLCSMGARPERAKACC
CCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQAVAFFKALADETRLKCVLLIQREGELCVCELMAALSEIQPKISRHLAQLKKAGILVDR
CHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
RQGQWVFYQINPELSAWCQQVLAQSCEANSPFLAESMQNLCSMGARPERAKACC
CCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]