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The map label for this gene is hemN [H]

Identifier: 113968874

GI number: 113968874

Start: 612936

End: 613823

Strand: Direct

Name: hemN [H]

Synonym: Shewmr4_0530

Alternate gene names: 113968874

Gene position: 612936-613823 (Clockwise)

Preceding gene: 113968872

Following gene: 113968876

Centisome position: 13.02

GC content: 48.2

Gene sequence:

>888_bases
GTGTTAATTAACTATATTGAGCCAGTGTTTAGACCGCCATCAGAATGGAAGTCGTTAATACTGCAAGTGACTAACGGTTG
TAGTTGGAATCAGTGCAGTTTTTGCGATATGTACACTCAGCCGCAAAAAGCCTTTAGGGCACAAAAGCTCGATAAGATTG
AGCAAGATATTCTCGCGATTGCCAAAACTGGGATGCCGGTATCACGGGTGTTTTTGGCTGATGGTGATGCTATGAGCTTA
CCCTTTGCCCGGTTAGAGGCGATTTGTGAGCTGATCAACCGACACTTGCCGCAGGTGACACGCATCAGCAGTTATTGTTT
GCCGCGCAATCTGAATAATAAAACTCCAGAGCAGCTCGCTCGGTTGCGGGAGTTAGGCCTAAGTCTGCTGTACGTTGGCT
GTGAAAGTGGTGATGACGAAGTGCTGGCCAAGATCAAAAAGGGCGAAACCTTCGAGTCATCGCTGGCGGCATTACAAAAA
ATTCGCGCGGCTGGGATGAAGTCATCTGTGATGATCCTCAATGGCTTAGGCGGCGTGGCATTATCGCAGCAACATGCCAT
CAACTCGGCCAAGTTGATGAATGCTGCCCAGCCCGATTATTTATCCACATTGGTAGTCACTTTACCGCTAGGCACTGAGC
GAATGGACGCTGTATTTGGCGGGCAATTTCAGTTGCCGGATCAAATGGGCTTGTTCCAAGAAATGCAGACCTTATTGGAT
CATTTGGAATTAGAGCAGACGATATTTAGATCCGATCATGCCTCTAACTATCTTGTGCTAAAAGGAGTATTAGGTAAGGA
CAAGGCCAAATTGCTGGCACAGGTCGAGCAGGCGATTAATGCGCCGCGCAGCATTCCCTTAAGGCAGGAATGGCAGCGCG
GTTTGTAA

Upstream 100 bases:

>100_bases
CATTATTTCATCAGATGATGCCCGAGTTAGTCGAGTCTTTCCATGTGGAATCCTATCATCAATTCATCGCCTAATTTATC
TGGTTTAACAGGAGTTTGCA

Downstream 100 bases:

>100_bases
TTGATCACCGAGTAAAAAGCCCCAGAAAGATGCCGGGGCTTTTTTATTGGAAACAGATTAGCAGCGCTTAGAAATTATAA
CGCACGCTGACTTTGTAGCT

Product: radical SAM domain-containing protein

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLINYIEPVFRPPSEWKSLILQVTNGCSWNQCSFCDMYTQPQKAFRAQKLDKIEQDILAIAKTGMPVSRVFLADGDAMSL
PFARLEAICELINRHLPQVTRISSYCLPRNLNNKTPEQLARLRELGLSLLYVGCESGDDEVLAKIKKGETFESSLAALQK
IRAAGMKSSVMILNGLGGVALSQQHAINSAKLMNAAQPDYLSTLVVTLPLGTERMDAVFGGQFQLPDQMGLFQEMQTLLD
HLELEQTIFRSDHASNYLVLKGVLGKDKAKLLAQVEQAINAPRSIPLRQEWQRGL

Sequences:

>Translated_295_residues
MLINYIEPVFRPPSEWKSLILQVTNGCSWNQCSFCDMYTQPQKAFRAQKLDKIEQDILAIAKTGMPVSRVFLADGDAMSL
PFARLEAICELINRHLPQVTRISSYCLPRNLNNKTPEQLARLRELGLSLLYVGCESGDDEVLAKIKKGETFESSLAALQK
IRAAGMKSSVMILNGLGGVALSQQHAINSAKLMNAAQPDYLSTLVVTLPLGTERMDAVFGGQFQLPDQMGLFQEMQTLLD
HLELEQTIFRSDHASNYLVLKGVLGKDKAKLLAQVEQAINAPRSIPLRQEWQRGL
>Mature_295_residues
MLINYIEPVFRPPSEWKSLILQVTNGCSWNQCSFCDMYTQPQKAFRAQKLDKIEQDILAIAKTGMPVSRVFLADGDAMSL
PFARLEAICELINRHLPQVTRISSYCLPRNLNNKTPEQLARLRELGLSLLYVGCESGDDEVLAKIKKGETFESSLAALQK
IRAAGMKSSVMILNGLGGVALSQQHAINSAKLMNAAQPDYLSTLVVTLPLGTERMDAVFGGQFQLPDQMGLFQEMQTLLD
HLELEQTIFRSDHASNYLVLKGVLGKDKAKLLAQVEQAINAPRSIPLRQEWQRGL

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 32848; Mature: 32848

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINYIEPVFRPPSEWKSLILQVTNGCSWNQCSFCDMYTQPQKAFRAQKLDKIEQDILAI
CCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
AKTGMPVSRVFLADGDAMSLPFARLEAICELINRHLPQVTRISSYCLPRNLNNKTPEQLA
HHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHH
RLRELGLSLLYVGCESGDDEVLAKIKKGETFESSLAALQKIRAAGMKSSVMILNGLGGVA
HHHHCCHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
LSQQHAINSAKLMNAAQPDYLSTLVVTLPLGTERMDAVFGGQFQLPDQMGLFQEMQTLLD
HHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
HLELEQTIFRSDHASNYLVLKGVLGKDKAKLLAQVEQAINAPRSIPLRQEWQRGL
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MLINYIEPVFRPPSEWKSLILQVTNGCSWNQCSFCDMYTQPQKAFRAQKLDKIEQDILAI
CCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
AKTGMPVSRVFLADGDAMSLPFARLEAICELINRHLPQVTRISSYCLPRNLNNKTPEQLA
HHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHH
RLRELGLSLLYVGCESGDDEVLAKIKKGETFESSLAALQKIRAAGMKSSVMILNGLGGVA
HHHHCCHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
LSQQHAINSAKLMNAAQPDYLSTLVVTLPLGTERMDAVFGGQFQLPDQMGLFQEMQTLLD
HHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
HLELEQTIFRSDHASNYLVLKGVLGKDKAKLLAQVEQAINAPRSIPLRQEWQRGL
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]