Click here to switch to the map view.

The map label for this gene is ttdR [H]

Identifier: 113968752

GI number: 113968752

Start: 454434

End: 455351

Strand: Direct

Name: ttdR [H]

Synonym: Shewmr4_0408

Alternate gene names: 113968752

Gene position: 454434-455351 (Clockwise)

Preceding gene: 113968749

Following gene: 113968755

Centisome position: 9.66

GC content: 49.24

Gene sequence:

>918_bases
ATGCTGCTGAATGATCTCGCACTATTTGTTCGCGTTGCCGATTGCGGCAGTATTTCTGCAGCGGCTGCCGAGATGGAGCT
TTCTGCGGCTTCGGCCAGTGCAGCGATTAAACGCCTAGAAAAACAGCTTGATACTAGTTTATTTGTGCGCACGACCCGTA
GCCTTAGGTTAACCGCCCAAGGTGAGCGTTATCTAATCCATTGCCGCCGTGCCTTAAGTGATCTCGCCCTCGGAGAGCAG
GCGATCGCCAGCGATAAAGGCAAGATATCTGGCACCTTGAGCCTATCGGTTTCATCCGACTTTGGGCGCAACTTATTTGT
CCCTTGGCTCGATGACTTCCTGTTAGATTTTCCGCAGCTACAAGTACGTTTGCATTTAGGCGATAACATCAGCAGCTTTT
ACCACGACAAAATCGATGTCGCGGTGCGTTACGGTAAGCCGCAGGATTCAAATCAGGTCGCCTTCCCGATTTGTTCTGTT
GATAGGGTGTTATGTGCTTCGCCTGAATATCTAGCAAAGTTTGGCAAACCCGAAACCTTAGAGCAGCTAACTCAACACAA
TTGCTTGTTTTATAAGTTAGATGATAGAACCCATGACCAATGGCAATTTGAACGGGATGGGCAAGAATTTAAAATCCGCG
TCACGGGGAATCGTAGTGCGAACGATGCGGAAATTGCACGCCGCTGGGCAGTTGCAGGGAAGGGCTTAGTATTTAAATCG
AGCCTAGATCTGGCTGAAGATATTATGGCGGGGCGCCTTGTGCCCTTGCTGCCTGAATATCGAGGAGAGGCGGTTAATCT
ATACTTAGTGTGCCCTGGGCGTGAGCATGTCACACCCGTCGTGCTATTGCTGCGCGAAATGCTTAGACAACAGACCCAAA
CTTTAAGCCGTGCCTTGGTGGTGTATTTAAAATCTTAA

Upstream 100 bases:

>100_bases
ACTCGTGTCTGTACTTGTCAATGGCAACTATTGTGTGGAATATTAAAGCCTAGATAAACGGGGTAAACTTTGTAATTTTT
TCAAAGGATTTTTGAAAATC

Downstream 100 bases:

>100_bases
ACGCAGTTTACACGCCATTTGAATTCAAACCTGATTTGAACCTTTGATGTTTAGCGATGAAGCGACGATGGCTATGCCCC
GTTAAAGGCTGTTTAATGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLLNDLALFVRVADCGSISAAAAEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGKPETLEQLTQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGEAVNLYLVCPGREHVTPVVLLLREMLRQQTQTLSRALVVYLKS

Sequences:

>Translated_305_residues
MLLNDLALFVRVADCGSISAAAAEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGKPETLEQLTQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGEAVNLYLVCPGREHVTPVVLLLREMLRQQTQTLSRALVVYLKS
>Mature_305_residues
MLLNDLALFVRVADCGSISAAAAEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGKPETLEQLTQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGEAVNLYLVCPGREHVTPVVLLLREMLRQQTQTLSRALVVYLKS

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=270, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=33.5640138408304, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1786401, Length=254, Percent_Identity=31.8897637795276, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=31.4878892733564, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789639, Length=268, Percent_Identity=30.2238805970149, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=24.6376811594203, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=26.8817204301075, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786448, Length=277, Percent_Identity=29.2418772563177, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789173, Length=279, Percent_Identity=27.5985663082437, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=237, Percent_Identity=24.0506329113924, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=129, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34148; Mature: 34148

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNDLALFVRVADCGSISAAAAEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQ
CCHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDDFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCEECHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSVDRVLCASPEYLAKFGKPETL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCCHHHHHCCCCHHH
EQLTQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLAEDIMAGRLVPLLPEYRGEAVNLYLVCPGREHVTPVVLLLREMLRQQTQTLSRALV
CCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHE
VYLKS
EEECC
>Mature Secondary Structure
MLLNDLALFVRVADCGSISAAAAEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQ
CCHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDDFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCEECHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSVDRVLCASPEYLAKFGKPETL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCCHHHHHCCCCHHH
EQLTQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLAEDIMAGRLVPLLPEYRGEAVNLYLVCPGREHVTPVVLLLREMLRQQTQTLSRALV
CCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHE
VYLKS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]