| Definition | Shewanella sp. MR-4 chromosome, complete genome. |
|---|---|
| Accession | NC_008321 |
| Length | 4,706,287 |
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The map label for this gene is kynU [H]
Identifier: 113968639
GI number: 113968639
Start: 314761
End: 315885
Strand: Direct
Name: kynU [H]
Synonym: Shewmr4_0295
Alternate gene names: 113968639
Gene position: 314761-315885 (Clockwise)
Preceding gene: 113968638
Following gene: 113968643
Centisome position: 6.69
GC content: 52.71
Gene sequence:
>1125_bases ATGCTGCTAAATGTAAAACAAGACTTTTGCCTCGCAGGCCCAGGCTATCTGCTCAACCATTCCGTGGGGCGGCCACTTAA ATCGACCGAGCAGGCGTTTAAGCAGGCATTTTTTGCGCCTTGGCAGGAGTCTGGCCGCGAGCCTTGGGGCCAATGGTTGG GCGTCATCGATAACTTTACCGCGGCGCTGGCGAGCCTTTTTAATGGTCAGCCGCAGGACTTTTGCCCGCAGGTGAATCTA TCGAGCGCCTTGACCAAAATTGTGATATCCCTCGATAGATTAACGCGAGATGGCGGCGCCGTGGTGCTGATGAGCGAGAT TGATTTTCCCAGCATGGGGTTTGCCCTGAAAAAGGCATTGCCCGCAAGCTGTGAACTGCGCTTTATTCCCAAGGGTTTAG ATGTCACCGACCCCAATGTGTGGGACGCGCATATTTGTGCCGATGTCGATTTAGTCTTTGTCAGCCATGCCTATTCTAAT ACTGGTCAGCAGGCGCCATTGGCGCAGATCATTCCCCTTGCCCGTGAGCGTGGCTGCTTGAGTCTCGTGGATGTGGCGCA ATCGGCTGGGATTTTACCGCTGGATTTAGCCAAGCTACAGCCGGACTTTATGATTGGTTCGAGTGTGAAATGGTTATGCT CAGGCCCAGGGGCTGCGTATCTGTGGGTCAATCCGGCTATTTTGCCCCAGTGTCAGCCGCAGGATGTGGGTTGGTTTAGC CATGAAAATCCCTTCGAGTTTGATATCCATGATTTCCGCTATCACCCAACTGCGCTGCGGTTTTGGGGCGGTACACCTTC TATCGCGCCCTATGCGATTGCCGCTCACAGCATTGAATATTTTGCCAATATTGGTTCACAGGTGATGCGTGAACATAACT TGCAGTTGATGGATACGGTCGTCCAAACATTGGAATGTGATTTGGTCTCGCCACGGGAAGTCGATAAGCGCAGTGGCACC TTGATCCTGCAATTTGGCGAGCGACAAGCACCCATCATGGCGGCGTTGGCGGAGGCGAATATCAGTGTCGATGCCCGCAG TTTAGGAATGCGCGTATCGCCGCATATCTATAACGATGAGGCCGATATCGCGAAATTGCTGGAGGTGATAAAAGCCCATC GTTAA
Upstream 100 bases:
>100_bases CTCGAGCGCTTAAGGGATAGACGCGCCGCGGTGTTGCGACACGATATTCGCACCCGTTATCACGATCTGAAAAAACTCAA AGACAGTTTAAGGTAAGGCC
Downstream 100 bases:
>100_bases CGGATTGAACAGGGCTTGCTCGGAACGGCTATGAATGGGGTGCGCTAAGGCGACCTAGTTGCACCCCTATGCTTAAATAC TGTAGTTATAGCGGCAGAAC
Product: aminotransferase, class V
Products: NA
Alternate protein names: L-kynurenine hydrolase [H]
Number of amino acids: Translated: 374; Mature: 374
Protein sequence:
>374_residues MLLNVKQDFCLAGPGYLLNHSVGRPLKSTEQAFKQAFFAPWQESGREPWGQWLGVIDNFTAALASLFNGQPQDFCPQVNL SSALTKIVISLDRLTRDGGAVVLMSEIDFPSMGFALKKALPASCELRFIPKGLDVTDPNVWDAHICADVDLVFVSHAYSN TGQQAPLAQIIPLARERGCLSLVDVAQSAGILPLDLAKLQPDFMIGSSVKWLCSGPGAAYLWVNPAILPQCQPQDVGWFS HENPFEFDIHDFRYHPTALRFWGGTPSIAPYAIAAHSIEYFANIGSQVMREHNLQLMDTVVQTLECDLVSPREVDKRSGT LILQFGERQAPIMAALAEANISVDARSLGMRVSPHIYNDEADIAKLLEVIKAHR
Sequences:
>Translated_374_residues MLLNVKQDFCLAGPGYLLNHSVGRPLKSTEQAFKQAFFAPWQESGREPWGQWLGVIDNFTAALASLFNGQPQDFCPQVNL SSALTKIVISLDRLTRDGGAVVLMSEIDFPSMGFALKKALPASCELRFIPKGLDVTDPNVWDAHICADVDLVFVSHAYSN TGQQAPLAQIIPLARERGCLSLVDVAQSAGILPLDLAKLQPDFMIGSSVKWLCSGPGAAYLWVNPAILPQCQPQDVGWFS HENPFEFDIHDFRYHPTALRFWGGTPSIAPYAIAAHSIEYFANIGSQVMREHNLQLMDTVVQTLECDLVSPREVDKRSGT LILQFGERQAPIMAALAEANISVDARSLGMRVSPHIYNDEADIAKLLEVIKAHR >Mature_374_residues MLLNVKQDFCLAGPGYLLNHSVGRPLKSTEQAFKQAFFAPWQESGREPWGQWLGVIDNFTAALASLFNGQPQDFCPQVNL SSALTKIVISLDRLTRDGGAVVLMSEIDFPSMGFALKKALPASCELRFIPKGLDVTDPNVWDAHICADVDLVFVSHAYSN TGQQAPLAQIIPLARERGCLSLVDVAQSAGILPLDLAKLQPDFMIGSSVKWLCSGPGAAYLWVNPAILPQCQPQDVGWFS HENPFEFDIHDFRYHPTALRFWGGTPSIAPYAIAAHSIEYFANIGSQVMREHNLQLMDTVVQTLECDLVSPREVDKRSGT LILQFGERQAPIMAALAEANISVDARSLGMRVSPHIYNDEADIAKLLEVIKAHR
Specific function: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively [H]
COG id: COG3844
COG function: function code E; Kynureninase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the kynureninase family [H]
Homologues:
Organism=Caenorhabditis elegans, GI17550466, Length=395, Percent_Identity=22.2784810126582, Blast_Score=68, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000192 - InterPro: IPR010111 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF00266 Aminotran_5 [H]
EC number: =3.7.1.3 [H]
Molecular weight: Translated: 41170; Mature: 41170
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: PS00591 GLYCOSYL_HYDROL_F10
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLLNVKQDFCLAGPGYLLNHSVGRPLKSTEQAFKQAFFAPWQESGREPWGQWLGVIDNFT CEECCCCCCEECCCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHH AALASLFNGQPQDFCPQVNLSSALTKIVISLDRLTRDGGAVVLMSEIDFPSMGFALKKAL HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCC PASCELRFIPKGLDVTDPNVWDAHICADVDLVFVSHAYSNTGQQAPLAQIIPLARERGCL CCCCEEEEECCCCCCCCCCCCCHHHHCCEEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCH SLVDVAQSAGILPLDLAKLQPDFMIGSSVKWLCSGPGAAYLWVNPAILPQCQPQDVGWFS HHHHHHHHCCCCEEHHHHCCCCEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCC HENPFEFDIHDFRYHPTALRFWGGTPSIAPYAIAAHSIEYFANIGSQVMREHNLQLMDTV CCCCEEECHHHCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH VQTLECDLVSPREVDKRSGTLILQFGERQAPIMAALAEANISVDARSLGMRVSPHIYNDE HHHHHCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEHHHCCCEECCCEECCH ADIAKLLEVIKAHR HHHHHHHHHHHCCC >Mature Secondary Structure MLLNVKQDFCLAGPGYLLNHSVGRPLKSTEQAFKQAFFAPWQESGREPWGQWLGVIDNFT CEECCCCCCEECCCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHH AALASLFNGQPQDFCPQVNLSSALTKIVISLDRLTRDGGAVVLMSEIDFPSMGFALKKAL HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCC PASCELRFIPKGLDVTDPNVWDAHICADVDLVFVSHAYSNTGQQAPLAQIIPLARERGCL CCCCEEEEECCCCCCCCCCCCCHHHHCCEEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCH SLVDVAQSAGILPLDLAKLQPDFMIGSSVKWLCSGPGAAYLWVNPAILPQCQPQDVGWFS HHHHHHHHCCCCEEHHHHCCCCEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCC HENPFEFDIHDFRYHPTALRFWGGTPSIAPYAIAAHSIEYFANIGSQVMREHNLQLMDTV CCCCEEECHHHCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH VQTLECDLVSPREVDKRSGTLILQFGERQAPIMAALAEANISVDARSLGMRVSPHIYNDE HHHHHCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEHHHCCCEECCCEECCH ADIAKLLEVIKAHR HHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10567266 [H]