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The map label for this gene is yitJ [H]

Identifier: 113478068

GI number: 113478068

Start: 7212651

End: 7213541

Strand: Reverse

Name: yitJ [H]

Synonym: Tery_4692

Alternate gene names: 113478068

Gene position: 7213541-7212651 (Counterclockwise)

Preceding gene: 113478069

Following gene: 113478061

Centisome position: 93.08

GC content: 35.91

Gene sequence:

>891_bases
ATGAATAGATTTCGCAATGCGGTTAAATCAGGAGAATTTTTAATCACTGCTGAAGTAGCACCACCCAAAGGAGCTGACCC
AACTCACATGATTCAAATGGCTGAAACTCTCAAAGGTAGAGTTCATGCAGTTAATATTACTGATGGTAGTCGTGCCGTAT
TAAGAATGTCCTCATTAGCAGCTTCTATGATTTTGAAGAATGTGGGCATAGAACCAATATGTCAAGTAGCTTGTCGCGAT
CGTAACCGTATAGCTTTACAAGCTGACCTCATGGGAGCTTCAGCTTTAGGACTTCACAATATTTTGGCCTTGACTGGAGA
CCCTGTCAAAGTAGGAGACCATGAAAAAGCCAGAAGTGTATTTGACATGGAGTCCATTCGTCTATTACAAATGATTGCTA
AGTTAAACCAAGGCATAGACTGGAATGAAAAAGCTTTACCAGATGGATCAACAGATTTATTTGTAGGTGCTGCGGTAGAC
CCTCAGTCTCCTAGTTGGTCAGGATTAAAAAGACGGTTTGAACTTAAATTATTAGCAGGATCTCAATTTTTTCAAAGTCA
ATTAATTTCTGATTTTGATAAACTAGAAAAATTTATGAATCAAATTGCAGTTGATAGTAATAAGCCAATTTTAGCTGGAA
TATTTTTGCTAAAATCTGCCAAAAATGCTGCATTTATTAATAAATATGTACCCGGAATTGATATACCAGAACATATTATT
AATCGTTTAGCAAATGCAGAAAAACCTTTACAAGAAGGAATAAAAATTGCTGCCGAACAAGTTAAAATTTCAAGCAAAAT
TTGTCATGGAGTTCATCTTATGGCAGTCAAGAGAGAAGACTTAATTCCCCAAATATTAGATATGGCTGAAATTTCTCCAA
TTTCCAATTAG

Upstream 100 bases:

>100_bases
TGATTAATAACTAACAGCAATTTTTATCAGAGTTAATTTATCCAATAGTCATAACAAAAATTACCAACTTAACCATAACT
AAATAAATAAATACGAATAT

Downstream 100 bases:

>100_bases
AGACTAAATAAAAAAATAATAACTTTGTAGGGACTTGGGGTGGAACGTCCCTACTTTTGTGATCTACTTAAATAAAAGTG
GTGTAAGATTTATTTTTATA

Product: methylenetetrahydrofolate reductase

Products: NA

Alternate protein names: Homocysteine S-methyltransferase; S-methylmethionine:homocysteine methyltransferase; 5,10-methylenetetrahydrofolate reductase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLAASMILKNVGIEPICQVACRD
RNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSVFDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVD
PQSPSWSGLKRRFELKLLAGSQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN

Sequences:

>Translated_296_residues
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLAASMILKNVGIEPICQVACRD
RNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSVFDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVD
PQSPSWSGLKRRFELKLLAGSQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN
>Mature_296_residues
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLAASMILKNVGIEPICQVACRD
RNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSVFDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVD
PQSPSWSGLKRRFELKLLAGSQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003171
- InterPro:   IPR003726 [H]

Pfam domain/function: PF02219 MTHFR; PF02574 S-methyl_trans [H]

EC number: =2.1.1.10; =1.5.1.20 [H]

Molecular weight: Translated: 32379; Mature: 32379

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLA
CCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
ASMILKNVGIEPICQVACRDRNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSV
HHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHH
FDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVDPQSPSWSGLKRRFELKLLAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEEECC
SQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHH
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRFRNAVKSGEFLITAEVAPPKGADPTHMIQMAETLKGRVHAVNITDGSRAVLRMSSLA
CCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
ASMILKNVGIEPICQVACRDRNRIALQADLMGASALGLHNILALTGDPVKVGDHEKARSV
HHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHH
FDMESIRLLQMIAKLNQGIDWNEKALPDGSTDLFVGAAVDPQSPSWSGLKRRFELKLLAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEEECC
SQFFQSQLISDFDKLEKFMNQIAVDSNKPILAGIFLLKSAKNAAFINKYVPGIDIPEHII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHH
NRLANAEKPLQEGIKIAAEQVKISSKICHGVHLMAVKREDLIPQILDMAEISPISN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]