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The map label for this gene is trpS [H]

Identifier: 113478069

GI number: 113478069

Start: 7213707

End: 7214726

Strand: Reverse

Name: trpS [H]

Synonym: Tery_4693

Alternate gene names: 113478069

Gene position: 7214726-7213707 (Counterclockwise)

Preceding gene: 113478072

Following gene: 113478068

Centisome position: 93.09

GC content: 35.0

Gene sequence:

>1020_bases
ATGGGTAAACAGCGAGTACTCTCTGGAGTTCAACCAACTGGAAACCTTCATATTGGTAACTATTTAGGTGCAATTCGCAA
CTGGGTAGAAGGGCAAAAAGAATACGATAATTTTTTCTGTGTAGTAGATTTGCACGCTATCACAGTACCCCATAATCCTG
TTACTCTAGCTACAGATACCTATACTATTGCCGCTTTATATCTGGCCTGCGGTATAGACCTGAACTATTCTACCATATTC
GTTCAATCTCATATTCCTGCTCATAGTGAATTAACATGGTTTCTCAACTGTATTACTCCCCTAAATTGGTTGACAGATAT
GATTCAATTTAAGGAAAAAGCAATTAAACAAGGAGAGAATGTAGGTACAGGTTTATTAGATTATCCAGTTTTAATGGCTG
CAGATATTCTACTTTATGATGCAGATAAAGTTCCTGTTGGAGAAGACCAAAAACAACATTTAGAACTTACCCGCGATATA
GCAGTTAGGTTTAATCATCAATTTGGTCAGGGAAGAACTATATTAAAATTACCAGATCCTTTGATTAGAAAAGAGGGTGC
GCGGGTAATGAGTTTGACAGATGGTACTAGCAAAATGTCTAAATCTGACCCTTCAGAATTGAGTAGAATTAATCTATTAG
ACCCTCCAGATGTAATTACTAAAAAAATTAAACGTTGCAAAACAGATGTAATTAAAGGCCTGGAATTTGATAATCCTGAA
CGACCTGAATGTAATAATTTATTGACTCTTTATGAATTATTTTCAGCTAAAACAAAGGAAGAGGTAATCACAGAATGTCA
AGACCTAGGATGGGGTAAGTTTAAGCCTTTATTAACTGAGGCAACTATTGAAGCTTTAACACCAATTCAAACAAAATATA
AAGCAGTAATGGATGATCAAGGTTATCTCAAATCTGTTTTAGCTCAAGGAAAACAAAAAGCAGAAGCGATCGCTAATCAA
ACTCTAGAAAAAGTTAAAAAAGCTTTAGGTTATTCTGTGTTAATAGGCAATAAGGAATAG

Upstream 100 bases:

>100_bases
TTTTGTTTTTTGACTTCAGTGCAGAGAATATTTAATGAGGTACTAAATATGTTATTGTTAATTATTAATTAATTTTGAAC
AATTTAAAGTTAAAAAAATA

Downstream 100 bases:

>100_bases
GGCATATAAAAAAAATTATTTGTTAATAATTCATGGCTGATAACTTAAGGCTAAATGCTTACTATTGATTAATAACTAAC
AGCAATTTTTATCAGAGTTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MGKQRVLSGVQPTGNLHIGNYLGAIRNWVEGQKEYDNFFCVVDLHAITVPHNPVTLATDTYTIAALYLACGIDLNYSTIF
VQSHIPAHSELTWFLNCITPLNWLTDMIQFKEKAIKQGENVGTGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDI
AVRFNHQFGQGRTILKLPDPLIRKEGARVMSLTDGTSKMSKSDPSELSRINLLDPPDVITKKIKRCKTDVIKGLEFDNPE
RPECNNLLTLYELFSAKTKEEVITECQDLGWGKFKPLLTEATIEALTPIQTKYKAVMDDQGYLKSVLAQGKQKAEAIANQ
TLEKVKKALGYSVLIGNKE

Sequences:

>Translated_339_residues
MGKQRVLSGVQPTGNLHIGNYLGAIRNWVEGQKEYDNFFCVVDLHAITVPHNPVTLATDTYTIAALYLACGIDLNYSTIF
VQSHIPAHSELTWFLNCITPLNWLTDMIQFKEKAIKQGENVGTGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDI
AVRFNHQFGQGRTILKLPDPLIRKEGARVMSLTDGTSKMSKSDPSELSRINLLDPPDVITKKIKRCKTDVIKGLEFDNPE
RPECNNLLTLYELFSAKTKEEVITECQDLGWGKFKPLLTEATIEALTPIQTKYKAVMDDQGYLKSVLAQGKQKAEAIANQ
TLEKVKKALGYSVLIGNKE
>Mature_338_residues
GKQRVLSGVQPTGNLHIGNYLGAIRNWVEGQKEYDNFFCVVDLHAITVPHNPVTLATDTYTIAALYLACGIDLNYSTIFV
QSHIPAHSELTWFLNCITPLNWLTDMIQFKEKAIKQGENVGTGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDIA
VRFNHQFGQGRTILKLPDPLIRKEGARVMSLTDGTSKMSKSDPSELSRINLLDPPDVITKKIKRCKTDVIKGLEFDNPER
PECNNLLTLYELFSAKTKEEVITECQDLGWGKFKPLLTEATIEALTPIQTKYKAVMDDQGYLKSVLAQGKQKAEAIANQT
LEKVKKALGYSVLIGNKE

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=38.9728096676737, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI41352700, Length=170, Percent_Identity=50.5882352941176, Blast_Score=180, Evalue=1e-45,
Organism=Escherichia coli, GI1789786, Length=333, Percent_Identity=46.5465465465465, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.3293413173653, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.3293413173653, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=37.7521613832853, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=40.4255319148936, Blast_Score=250, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37922; Mature: 37791

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKQRVLSGVQPTGNLHIGNYLGAIRNWVEGQKEYDNFFCVVDLHAITVPHNPVTLATDT
CCHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCHHHCCEEEEEEEEEEEECCCCEEEEECH
YTIAALYLACGIDLNYSTIFVQSHIPAHSELTWFLNCITPLNWLTDMIQFKEKAIKQGEN
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGTGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDIAVRFNHQFGQGRTILKLPDP
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCH
LIRKEGARVMSLTDGTSKMSKSDPSELSRINLLDPPDVITKKIKRCKTDVIKGLEFDNPE
HHHHCCCEEEEECCCCHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RPECNNLLTLYELFSAKTKEEVITECQDLGWGKFKPLLTEATIEALTPIQTKYKAVMDDQ
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCH
GYLKSVLAQGKQKAEAIANQTLEKVKKALGYSVLIGNKE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC
>Mature Secondary Structure 
GKQRVLSGVQPTGNLHIGNYLGAIRNWVEGQKEYDNFFCVVDLHAITVPHNPVTLATDT
CHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCHHHCCEEEEEEEEEEEECCCCEEEEECH
YTIAALYLACGIDLNYSTIFVQSHIPAHSELTWFLNCITPLNWLTDMIQFKEKAIKQGEN
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGTGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDIAVRFNHQFGQGRTILKLPDP
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCH
LIRKEGARVMSLTDGTSKMSKSDPSELSRINLLDPPDVITKKIKRCKTDVIKGLEFDNPE
HHHHCCCEEEEECCCCHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RPECNNLLTLYELFSAKTKEEVITECQDLGWGKFKPLLTEATIEALTPIQTKYKAVMDDQ
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCH
GYLKSVLAQGKQKAEAIANQTLEKVKKALGYSVLIGNKE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]