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The map label for this gene is btuR [C]

Identifier: 113478061

GI number: 113478061

Start: 7203688

End: 7204821

Strand: Reverse

Name: btuR [C]

Synonym: Tery_4685

Alternate gene names: 113478061

Gene position: 7204821-7203688 (Counterclockwise)

Preceding gene: 113478068

Following gene: 113478060

Centisome position: 92.96

GC content: 40.3

Gene sequence:

>1134_bases
ATGAGAAGAAACGGCATTGGTATACGCACTGCACAACTCATGTCAGAAAGAATTGTGGGGCAAATTCATGTTTACGATGG
AGCAAGTAAAGGTAAATCTCAGGCAGCTTTGGGAGTAGTTTTACGTTCTATTGGCCTTGGCATACATTCTGACTCTCCTA
CTAGAGTATTATTACTGAGATTTCTCAAAGGTCCTGACCGCTCCTATGATGAAGATGCTGCGATAGAAGCACTACAAAAA
GGCTTTCCTCATCTGATAGACCAAGTACGCACAGGTCGTTCTGAGTACTTTGGGCCTGAACAAATCACTCAATTTGACCA
TCAAGAAGCACAACGTGGTTGGGATGTGGTTAAAGGAGCGATCGCTTCTGACCTCTACTCAGTGGTCGTATTAGATGAAT
TAAACCCTGTTTTGGACTTAGGTTTATTACCAGTGGATGAAGTAATTAATACTATCAAGAACAAACCAGAACAATTAGAA
ATTATCGCTACAGGTCGTGCAGCTCCTCAAGGTTTGTTGGACATAGCTGACTTACATTCAGAAATGAAACCCCATCAAAA
TTCCACTGCTCAAAGTCATGGTATAACTGGGATTGAGATTTATACTGGTGCTGGTAAGGGCAAATCTACTAGTGCTTTGG
GAAAAGCATTACAGGCAATAGGTCGGGGTATTAGTCAAGACCAGTCTCATAGGGTCTTAATTATACAATGGCTTAAAGGA
GGTATTGGTTATACAGAAGATGCAGCGATCGCTGCTTTGCGCCAAAGTTATCCGAATTTAGTAGATCATCAACGTTGTGG
TGGAGATGCCATTGTTTGGCGTGGGCAACAAAAAGAAATAGATTTTGTTGAAGCAGAAAGAGGTTGGGAAATAGCTAGGG
CTGCTATTGCATCTGGTTTGTATAAGACTATTATTTTAGATGAGCTTAATCCTACTGTAGATTTAGAGTTATTGCCTGTC
AAGCCAATAGTTGAAGCTTTATTACGCAAACCAAAAGATACAGAGGTCATTATTACTGGTCGTTGTCTTAACCCGCCTGA
TTATTTTGATTTAGCTAGTGTTCATTCAGAAGTCTTTTGCCATAAGCATTATGCTAATCATGGAGTGGAATTAAAACCTG
GAGTAGATTTTTGA

Upstream 100 bases:

>100_bases
TCATTCATTCATCCTCCTTCCTTTCTAGCTCATTCCCATTGAGAAGCGCTATATTAACTAGATAACCAAAATCAAAAATC
ACAAACCTCAAATAACCCTT

Downstream 100 bases:

>100_bases
AGAATGAAGGCAGTGCCGGAATAAGCAAGAACTAGGAAGGTAGGTAGGGAAGCAGAAGGTTTGCTAACTACTGATATTTT
TTTGCTCTCAACTATTCTCA

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRRNGIGIRTAQLMSERIVGQIHVYDGASKGKSQAALGVVLRSIGLGIHSDSPTRVLLLRFLKGPDRSYDEDAAIEALQK
GFPHLIDQVRTGRSEYFGPEQITQFDHQEAQRGWDVVKGAIASDLYSVVVLDELNPVLDLGLLPVDEVINTIKNKPEQLE
IIATGRAAPQGLLDIADLHSEMKPHQNSTAQSHGITGIEIYTGAGKGKSTSALGKALQAIGRGISQDQSHRVLIIQWLKG
GIGYTEDAAIAALRQSYPNLVDHQRCGGDAIVWRGQQKEIDFVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPV
KPIVEALLRKPKDTEVIITGRCLNPPDYFDLASVHSEVFCHKHYANHGVELKPGVDF

Sequences:

>Translated_377_residues
MRRNGIGIRTAQLMSERIVGQIHVYDGASKGKSQAALGVVLRSIGLGIHSDSPTRVLLLRFLKGPDRSYDEDAAIEALQK
GFPHLIDQVRTGRSEYFGPEQITQFDHQEAQRGWDVVKGAIASDLYSVVVLDELNPVLDLGLLPVDEVINTIKNKPEQLE
IIATGRAAPQGLLDIADLHSEMKPHQNSTAQSHGITGIEIYTGAGKGKSTSALGKALQAIGRGISQDQSHRVLIIQWLKG
GIGYTEDAAIAALRQSYPNLVDHQRCGGDAIVWRGQQKEIDFVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPV
KPIVEALLRKPKDTEVIITGRCLNPPDYFDLASVHSEVFCHKHYANHGVELKPGVDF
>Mature_377_residues
MRRNGIGIRTAQLMSERIVGQIHVYDGASKGKSQAALGVVLRSIGLGIHSDSPTRVLLLRFLKGPDRSYDEDAAIEALQK
GFPHLIDQVRTGRSEYFGPEQITQFDHQEAQRGWDVVKGAIASDLYSVVVLDELNPVLDLGLLPVDEVINTIKNKPEQLE
IIATGRAAPQGLLDIADLHSEMKPHQNSTAQSHGITGIEIYTGAGKGKSTSALGKALQAIGRGISQDQSHRVLIIQWLKG
GIGYTEDAAIAALRQSYPNLVDHQRCGGDAIVWRGQQKEIDFVEAERGWEIARAAIASGLYKTIILDELNPTVDLELLPV
KPIVEALLRKPKDTEVIITGRCLNPPDYFDLASVHSEVFCHKHYANHGVELKPGVDF

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=180, Percent_Identity=31.6666666666667, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 41275; Mature: 41275

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNGIGIRTAQLMSERIVGQIHVYDGASKGKSQAALGVVLRSIGLGIHSDSPTRVLLLR
CCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FLKGPDRSYDEDAAIEALQKGFPHLIDQVRTGRSEYFGPEQITQFDHQEAQRGWDVVKGA
HHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IASDLYSVVVLDELNPVLDLGLLPVDEVINTIKNKPEQLEIIATGRAAPQGLLDIADLHS
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
EMKPHQNSTAQSHGITGIEIYTGAGKGKSTSALGKALQAIGRGISQDQSHRVLIIQWLKG
HHCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
GIGYTEDAAIAALRQSYPNLVDHQRCGGDAIVWRGQQKEIDFVEAERGWEIARAAIASGL
CCCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCHHCCCCCHHHHHHHHHHHH
YKTIILDELNPTVDLELLPVKPIVEALLRKPKDTEVIITGRCLNPPDYFDLASVHSEVFC
HHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
HKHYANHGVELKPGVDF
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRRNGIGIRTAQLMSERIVGQIHVYDGASKGKSQAALGVVLRSIGLGIHSDSPTRVLLLR
CCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FLKGPDRSYDEDAAIEALQKGFPHLIDQVRTGRSEYFGPEQITQFDHQEAQRGWDVVKGA
HHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IASDLYSVVVLDELNPVLDLGLLPVDEVINTIKNKPEQLEIIATGRAAPQGLLDIADLHS
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
EMKPHQNSTAQSHGITGIEIYTGAGKGKSTSALGKALQAIGRGISQDQSHRVLIIQWLKG
HHCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
GIGYTEDAAIAALRQSYPNLVDHQRCGGDAIVWRGQQKEIDFVEAERGWEIARAAIASGL
CCCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCHHCCCCCHHHHHHHHHHHH
YKTIILDELNPTVDLELLPVKPIVEALLRKPKDTEVIITGRCLNPPDYFDLASVHSEVFC
HHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
HKHYANHGVELKPGVDF
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]