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The map label for this gene is hetI [H]

Identifier: 113478060

GI number: 113478060

Start: 7202068

End: 7202805

Strand: Reverse

Name: hetI [H]

Synonym: Tery_4684

Alternate gene names: 113478060

Gene position: 7202805-7202068 (Counterclockwise)

Preceding gene: 113478061

Following gene: 113478059

Centisome position: 92.94

GC content: 30.89

Gene sequence:

>738_bases
ATGTTACTTGATCAGGCAGAAAAAAAATTCGAGCTATCAGAAAATAACGTTCATATATGGAGTACAAACCTAAAATTATC
ATCTGATAAAATTGAGGAATTATCAACAATATTATCGCCAGATGAAAAAAATAGAGCCAACAAATTTTATTTTGAAAAAG
ACAAAAATCGCTTTATAATTGCCAGAGGAACACTCAGAACAATTCTCAGCCGTTACTTAAACATTGAACCAAAAAAACTA
CAATTTACTTATAGCGATCGCGGCAAACCCTACTTAAAAAATACTTCAATATTATTTAACCTATCCCACTCTCAAGACTT
AGCCTTATATGGCATTACCAAAATTAACTTAATAGGAATTGACTTAGAATATATCCGCCCAATGAATGATGCTGTAAATT
TAGCAAAACGTTTTTTTTCTCTTCAAGAATACAAGCTTATTAGTCAACTTCCTCCTCAAAAACAACAAGAAACATTTTTT
AAAATATGGACTTGCAAAGAAGCTTATTTAAAAGCAACAGGAGATGGACTAGCAGGTCATCTAGAAAAAGTAGAAATTTG
TTTAACCCCAGAAAAACCAGTAGAATTTTTTAGTATTAATGGAGATATTGAGGCAGCATCTCATTGGTATTTATATCAAT
TTATTCCTCAACCCAATTATATAGCTGCCGTAGTAGTAGCAGAGAAAAATCAAAAGTTGAGTTTTTGGCAGATAAATAAT
ACTGACATTGTTTTTTGA

Upstream 100 bases:

>100_bases
GTTGCATTTAGCAATCAGTTGTAGTAGTCTAGATATAAGGGGGCGTTCGTCTATATACATGATTTTTTATTCAACTAAAA
AAAATACATTCCAAAAATAA

Downstream 100 bases:

>100_bases
AATGCTTATTATCAGAAAATATAGCAATCCCAAATAGGTTAAATAAAACAAAACTTACTCATATAGAATGAGACACAAAT
ACACAAGTATTTAATTATAA

Product: phosphopantethiene-protein transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLLDQAEKKFELSENNVHIWSTNLKLSSDKIEELSTILSPDEKNRANKFYFEKDKNRFIIARGTLRTILSRYLNIEPKKL
QFTYSDRGKPYLKNTSILFNLSHSQDLALYGITKINLIGIDLEYIRPMNDAVNLAKRFFSLQEYKLISQLPPQKQQETFF
KIWTCKEAYLKATGDGLAGHLEKVEICLTPEKPVEFFSINGDIEAASHWYLYQFIPQPNYIAAVVVAEKNQKLSFWQINN
TDIVF

Sequences:

>Translated_245_residues
MLLDQAEKKFELSENNVHIWSTNLKLSSDKIEELSTILSPDEKNRANKFYFEKDKNRFIIARGTLRTILSRYLNIEPKKL
QFTYSDRGKPYLKNTSILFNLSHSQDLALYGITKINLIGIDLEYIRPMNDAVNLAKRFFSLQEYKLISQLPPQKQQETFF
KIWTCKEAYLKATGDGLAGHLEKVEICLTPEKPVEFFSINGDIEAASHWYLYQFIPQPNYIAAVVVAEKNQKLSFWQINN
TDIVF
>Mature_245_residues
MLLDQAEKKFELSENNVHIWSTNLKLSSDKIEELSTILSPDEKNRANKFYFEKDKNRFIIARGTLRTILSRYLNIEPKKL
QFTYSDRGKPYLKNTSILFNLSHSQDLALYGITKINLIGIDLEYIRPMNDAVNLAKRFFSLQEYKLISQLPPQKQQETFF
KIWTCKEAYLKATGDGLAGHLEKVEICLTPEKPVEFFSINGDIEAASHWYLYQFIPQPNYIAAVVVAEKNQKLSFWQINN
TDIVF

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=165, Percent_Identity=27.8787878787879, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789886, Length=110, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24663173, Length=264, Percent_Identity=23.4848484848485, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 28528; Mature: 28528

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDQAEKKFELSENNVHIWSTNLKLSSDKIEELSTILSPDEKNRANKFYFEKDKNRFII
CCCCCCCCCEEECCCCEEEEEECEEECHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEE
ARGTLRTILSRYLNIEPKKLQFTYSDRGKPYLKNTSILFNLSHSQDLALYGITKINLIGI
ECCHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCEEEEEECCCCCEEEEEEEEEEEEEE
DLEYIRPMNDAVNLAKRFFSLQEYKLISQLPPQKQQETFFKIWTCKEAYLKATGDGLAGH
EHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHHEEECCCCCCCC
LEKVEICLTPEKPVEFFSINGDIEAASHWYLYQFIPQPNYIAAVVVAEKNQKLSFWQINN
CEEEEEEECCCCCEEEEEECCCEECCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECC
TDIVF
CEEEC
>Mature Secondary Structure
MLLDQAEKKFELSENNVHIWSTNLKLSSDKIEELSTILSPDEKNRANKFYFEKDKNRFII
CCCCCCCCCEEECCCCEEEEEECEEECHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEE
ARGTLRTILSRYLNIEPKKLQFTYSDRGKPYLKNTSILFNLSHSQDLALYGITKINLIGI
ECCHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCEEEEEECCCCCEEEEEEEEEEEEEE
DLEYIRPMNDAVNLAKRFFSLQEYKLISQLPPQKQQETFFKIWTCKEAYLKATGDGLAGH
EHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHHEEECCCCCCCC
LEKVEICLTPEKPVEFFSINGDIEAASHWYLYQFIPQPNYIAAVVVAEKNQKLSFWQINN
CEEEEEEECCCCCEEEEEECCCEECCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECC
TDIVF
CEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]