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The map label for this gene is nadB [H]

Identifier: 113476079

GI number: 113476079

Start: 3779360

End: 3779986

Strand: Direct

Name: nadB [H]

Synonym: Tery_2455

Alternate gene names: 113476079

Gene position: 3779360-3779986 (Clockwise)

Preceding gene: 113476078

Following gene: 113476082

Centisome position: 48.77

GC content: 43.86

Gene sequence:

>627_bases
TTGTGGTTAGCCACACAAAAGGCTCGGGTTCAAGGTATTAGTCTTCTTCACGAAAGTAAAATCCAATGTTTAAAATCCTC
TGTAGTAGTTTTGGCAACAGGTGGAGGCGGTCAAATATTTGCCCAAACTACTAATCCTGAGGTGAGTACGGGGAATGGAA
TTGCTATAGCGTGGCGTGCCGGGGCAGTTTTGCGAGATTTGGAATTTTTCCAATTTCATCCTACTGCCTTAATTAAACCA
GGAGCACCTCGTTTTCTCATTAGTGAAGCTGTTCGTGGAGAAGGAGCGCACCTAATAGACAATAAGGGAAACCGCTTTGC
CTTTGAGTATCATCCGGCTGGAGAGTTAGCTCCTAGAGATGTTGTCAGTAGAGCTATTTTCCATCATTTGCACAAAACTG
CTACCAAGCCTACCAATGCTCATGTTTATTTGGACTTGCGAGCCATTGACTCAGACCGCGTTCGCGACAGATTTCCCAAT
ATTATCAATGTCTGTCAAAAATGGGGTATTGATGTTTTTCAAGAACCTATTCCGGTTGCTCCTGCTGCTCATTATTGGAT
GGGTGGAGTGGCTTGCGATCTAATGAGTCAGACTTCAATTCCCGGACTAATAGAATTTATCCCTTGA

Upstream 100 bases:

>100_bases
TTCAGCAGATACCACAGGTAGAGCTATTATTGATACACTCGTTATTGAAGCTCAAGAACGTCCAAATATTTAGATAATTT
CCCAGGCAGTAGCATTAAAT

Downstream 100 bases:

>100_bases
TTCAGCAACCCCTGAATTTGAGGCCATAGTCAGCCCAAAATACTAGCTTTTTGCACCGAAAAACTGGCACTTTCCTTTTT
GGCATCTACCTACTAAACTT

Product: fumarate reductase/succinate dehydrogenase flavoprotein-like protein

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MWLATQKARVQGISLLHESKIQCLKSSVVVLATGGGGQIFAQTTNPEVSTGNGIAIAWRAGAVLRDLEFFQFHPTALIKP
GAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRFPN
IINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLIEFIP

Sequences:

>Translated_208_residues
MWLATQKARVQGISLLHESKIQCLKSSVVVLATGGGGQIFAQTTNPEVSTGNGIAIAWRAGAVLRDLEFFQFHPTALIKP
GAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRFPN
IINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLIEFIP
>Mature_208_residues
MWLATQKARVQGISLLHESKIQCLKSSVVVLATGGGGQIFAQTTNPEVSTGNGIAIAWRAGAVLRDLEFFQFHPTALIKP
GAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRFPN
IINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLIEFIP

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=185, Percent_Identity=39.4594594594595, Blast_Score=128, Evalue=4e-30,
Organism=Escherichia coli, GI1788928, Length=187, Percent_Identity=44.9197860962567, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1790597, Length=204, Percent_Identity=38.7254901960784, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786942, Length=178, Percent_Identity=38.2022471910112, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17505833, Length=211, Percent_Identity=37.4407582938389, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17550100, Length=185, Percent_Identity=40, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71986328, Length=141, Percent_Identity=34.7517730496454, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322416, Length=195, Percent_Identity=38.974358974359, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322701, Length=193, Percent_Identity=37.3056994818653, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17137288, Length=185, Percent_Identity=39.4594594594595, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24655642, Length=185, Percent_Identity=39.4594594594595, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24655647, Length=185, Percent_Identity=39.4594594594595, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24663005, Length=168, Percent_Identity=41.0714285714286, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 22829; Mature: 22829

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLATQKARVQGISLLHESKIQCLKSSVVVLATGGGGQIFAQTTNPEVSTGNGIAIAWRA
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEC
GAVLRDLEFFQFHPTALIKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRD
CHHHHHHHHHEECCCEEECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCHHH
VVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRFPNIINVCQKWGIDVFQEPIPVA
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCHHHHHHHHHCCCHHHCCCCCCC
PAAHYWMGGVACDLMSQTSIPGLIEFIP
CCHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MWLATQKARVQGISLLHESKIQCLKSSVVVLATGGGGQIFAQTTNPEVSTGNGIAIAWRA
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEC
GAVLRDLEFFQFHPTALIKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRD
CHHHHHHHHHEECCCEEECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCHHH
VVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRFPNIINVCQKWGIDVFQEPIPVA
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCHHHHHHHHHCCCHHHCCCCCCC
PAAHYWMGGVACDLMSQTSIPGLIEFIP
CCHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]