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The map label for this gene is abcA [H]

Identifier: 113475086

GI number: 113475086

Start: 2089867

End: 2091285

Strand: Reverse

Name: abcA [H]

Synonym: Tery_1362

Alternate gene names: 113475086

Gene position: 2091285-2089867 (Counterclockwise)

Preceding gene: 113475087

Following gene: 113475085

Centisome position: 26.98

GC content: 31.85

Gene sequence:

>1419_bases
ATGATACCTGAAACTGTAATTTCACTACAAAATGTTTCTAAATGTTTTAAACGGTACCAACATCCTGTAGACCGTTTAAA
AGAAATTTTACTCCCTGGAAAAAGTTGTGCTGATGAATTTTGGGCAGTACAAAATATAAATATAGAAATAGAAAAAGGGC
ATACTTTAGGAATTGTAGGACGGAATGGTTCAGGAAAAAGTACTCTTTTACAAATAATTGTGGGAACTCTAACGCCAACA
ACAGGAAAAGTAAAAATTCAAGGGAGAATTTCTGCACTACTAGAACTTGGTAGTGGATTTAATCCAGAATTTACAGGGAG
ACAAAACGTTTTTTTTAACGGTCAACTATTAGGATTAAAAACATCAGAAATAGAAGCAAAATTTGACCAAATCGCTAGTT
TTGCCGATATTGGTGATTTTATTGACCAACCTGTAAAAACTTATTCTAGCGGAATGTTTATTAGATTAGGATTTGCTGTA
GCTACCAGTGTAGATCCAGATATTTTAGTAGTTGATGAAGCACTTTCAGTAGGAGATGAAGCATTTCAAAGAAAATGTTT
TGCACGTATTCAAGACATTCAAGAAAGAGGAGGTACAATTTTATTTGTGTCTCATGCTGCTTCAACAGTGGTTCAGCTTT
GTGACTCAGCAATTTTGATGGATCATGGGGAAATGTTGCTTTATCATACTCCTAAATATGTAGTTTCTAAATATCAGAAA
TTAATCTATGCTTTTCCAGATAAAATTCCATCAATAAGAGAAGAAATTCGCCAAATTCCTAATTTAACCATTCAAGATTT
ATTTGATGATCAAAATACAGATAAATCACCATCTAAATCGGCAATAAATAGTGAAAATCTAGATCAATATCAGATTGCAC
AATCAATAGAATACGAAGAAATTTATGATCCAGATATGATACCCTCAAATACCATACATTATCCTGATAAAGGAGCAAAA
ATTATTGACCCCCATATTATTACTTTGGAAGGTAAAAGGGTAAATCATTTAGTTAACCGCCGGGAATATTACTATACATA
TAGAGTAAAATTTATTAATTCAACATCCAAAATTAGGTTTGGAATGTTAATAAAAACTCTCAGTGGTTTTGAGTTAGGAG
GAGCATCTTTACATGGTTATACTAAATCAGTAGAATATATTGCAGCACAACAAATAGTTATAGTTAAATTTAGGTTCAAA
TGTTTACTAAATCCTGGTGTATATTTTTTAAATGCTGGAGTTGTTGGAATGGCAAACGATCATCTAACCTATTTATCCCG
TTGCATTGACATTGCAATGTTTAAAGTCCAACATTATAGTGATTCATGCGGTACAGGTGTCATTGACTTTTTAATAGAAC
CTAGCTTAAACATTGAGCATAATACTCTGAACAATAAAGCCAAAATTGAATCTATTTAA

Upstream 100 bases:

>100_bases
ATTCCTCCTTGGATATAATAAGAATAAGTTAATAACTTATTACAAATAGCCATCAGCTATTTGTACAGCATTCCCCAGGA
AACGCTTACATATAAAATCC

Downstream 100 bases:

>100_bases
AATAGAAATAGGGTAGAAAAAATCAGATTATTTCAGTTATTATTTATTAGTAGCAACTACTGAATCCTTATACTTCAAAT
ACCTATAGGGAATATTTTTT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MIPETVISLQNVSKCFKRYQHPVDRLKEILLPGKSCADEFWAVQNINIEIEKGHTLGIVGRNGSGKSTLLQIIVGTLTPT
TGKVKIQGRISALLELGSGFNPEFTGRQNVFFNGQLLGLKTSEIEAKFDQIASFADIGDFIDQPVKTYSSGMFIRLGFAV
ATSVDPDILVVDEALSVGDEAFQRKCFARIQDIQERGGTILFVSHAASTVVQLCDSAILMDHGEMLLYHTPKYVVSKYQK
LIYAFPDKIPSIREEIRQIPNLTIQDLFDDQNTDKSPSKSAINSENLDQYQIAQSIEYEEIYDPDMIPSNTIHYPDKGAK
IIDPHIITLEGKRVNHLVNRREYYYTYRVKFINSTSKIRFGMLIKTLSGFELGGASLHGYTKSVEYIAAQQIVIVKFRFK
CLLNPGVYFLNAGVVGMANDHLTYLSRCIDIAMFKVQHYSDSCGTGVIDFLIEPSLNIEHNTLNNKAKIESI

Sequences:

>Translated_472_residues
MIPETVISLQNVSKCFKRYQHPVDRLKEILLPGKSCADEFWAVQNINIEIEKGHTLGIVGRNGSGKSTLLQIIVGTLTPT
TGKVKIQGRISALLELGSGFNPEFTGRQNVFFNGQLLGLKTSEIEAKFDQIASFADIGDFIDQPVKTYSSGMFIRLGFAV
ATSVDPDILVVDEALSVGDEAFQRKCFARIQDIQERGGTILFVSHAASTVVQLCDSAILMDHGEMLLYHTPKYVVSKYQK
LIYAFPDKIPSIREEIRQIPNLTIQDLFDDQNTDKSPSKSAINSENLDQYQIAQSIEYEEIYDPDMIPSNTIHYPDKGAK
IIDPHIITLEGKRVNHLVNRREYYYTYRVKFINSTSKIRFGMLIKTLSGFELGGASLHGYTKSVEYIAAQQIVIVKFRFK
CLLNPGVYFLNAGVVGMANDHLTYLSRCIDIAMFKVQHYSDSCGTGVIDFLIEPSLNIEHNTLNNKAKIESI
>Mature_472_residues
MIPETVISLQNVSKCFKRYQHPVDRLKEILLPGKSCADEFWAVQNINIEIEKGHTLGIVGRNGSGKSTLLQIIVGTLTPT
TGKVKIQGRISALLELGSGFNPEFTGRQNVFFNGQLLGLKTSEIEAKFDQIASFADIGDFIDQPVKTYSSGMFIRLGFAV
ATSVDPDILVVDEALSVGDEAFQRKCFARIQDIQERGGTILFVSHAASTVVQLCDSAILMDHGEMLLYHTPKYVVSKYQK
LIYAFPDKIPSIREEIRQIPNLTIQDLFDDQNTDKSPSKSAINSENLDQYQIAQSIEYEEIYDPDMIPSNTIHYPDKGAK
IIDPHIITLEGKRVNHLVNRREYYYTYRVKFINSTSKIRFGMLIKTLSGFELGGASLHGYTKSVEYIAAQQIVIVKFRFK
CLLNPGVYFLNAGVVGMANDHLTYLSRCIDIAMFKVQHYSDSCGTGVIDFLIEPSLNIEHNTLNNKAKIESI

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=209, Percent_Identity=27.7511961722488, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=26.4150943396226, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI153792144, Length=289, Percent_Identity=22.4913494809689, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27436953, Length=192, Percent_Identity=26.5625, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI27477115, Length=284, Percent_Identity=24.6478873239437, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI105990541, Length=284, Percent_Identity=25, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI116734710, Length=210, Percent_Identity=25.2380952380952, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI30795238, Length=211, Percent_Identity=23.2227488151659, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI27881501, Length=211, Percent_Identity=23.2227488151659, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI27262624, Length=212, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI27262626, Length=212, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI150417984, Length=261, Percent_Identity=19.9233716475096, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=28.4313725490196, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=25.8706467661692, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI48994943, Length=210, Percent_Identity=27.1428571428571, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786398, Length=258, Percent_Identity=25.5813953488372, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787758, Length=238, Percent_Identity=27.7310924369748, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790467, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786319, Length=209, Percent_Identity=25.8373205741627, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789032, Length=215, Percent_Identity=26.9767441860465, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=23.0392156862745, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=209, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787547, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788450, Length=213, Percent_Identity=26.2910798122066, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=22.0720720720721, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787041, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787029, Length=220, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=200, Percent_Identity=26.5, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786253, Length=192, Percent_Identity=26.5625, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=210, Percent_Identity=24.2857142857143, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=222, Percent_Identity=23.4234234234234, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17565938, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=204, Percent_Identity=26.9607843137255, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI116007184, Length=241, Percent_Identity=22.4066390041494, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221500365, Length=241, Percent_Identity=22.4066390041494, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573571, Length=200, Percent_Identity=26.5, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573573, Length=200, Percent_Identity=26.5, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666092, Length=210, Percent_Identity=25.2380952380952, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648314, Length=292, Percent_Identity=24.3150684931507, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643674, Length=214, Percent_Identity=24.7663551401869, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24650853, Length=210, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24650855, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281362751, Length=210, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62484234, Length=248, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512771, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550390, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24582014, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24582012, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 52887; Mature: 52887

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00189 LIPOYL ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPETVISLQNVSKCFKRYQHPVDRLKEILLPGKSCADEFWAVQNINIEIEKGHTLGIVG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHEEEECEEEEECCCEEEEEE
RNGSGKSTLLQIIVGTLTPTTGKVKIQGRISALLELGSGFNPEFTGRQNVFFNGQLLGLK
CCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEE
TSEIEAKFDQIASFADIGDFIDQPVKTYSSGMFIRLGFAVATSVDPDILVVDEALSVGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEEECHHHCCHH
AFQRKCFARIQDIQERGGTILFVSHAASTVVQLCDSAILMDHGEMLLYHTPKYVVSKYQK
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCHHEECCCCEEEEECCHHHHHHHHH
LIYAFPDKIPSIREEIRQIPNLTIQDLFDDQNTDKSPSKSAINSENLDQYQIAQSIEYEE
HHHHCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHH
IYDPDMIPSNTIHYPDKGAKIIDPHIITLEGKRVNHLVNRREYYYTYRVKFINSTSKIRF
CCCCCCCCCCCEECCCCCCEEECCEEEEECCHHHHHHHCCCEEEEEEEEEEECCCCCCHH
GMLIKTLSGFELGGASLHGYTKSVEYIAAQQIVIVKFRFKCLLNPGVYFLNAGVVGMAND
HHHHHHHCCCCCCCCEECCHHHHHHHHHHCEEEEEEEEEEEEECCCEEEEECCEEEECCC
HLTYLSRCIDIAMFKVQHYSDSCGTGVIDFLIEPSLNIEHNTLNNKAKIESI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCEEECCC
>Mature Secondary Structure
MIPETVISLQNVSKCFKRYQHPVDRLKEILLPGKSCADEFWAVQNINIEIEKGHTLGIVG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHEEEECEEEEECCCEEEEEE
RNGSGKSTLLQIIVGTLTPTTGKVKIQGRISALLELGSGFNPEFTGRQNVFFNGQLLGLK
CCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEE
TSEIEAKFDQIASFADIGDFIDQPVKTYSSGMFIRLGFAVATSVDPDILVVDEALSVGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCEEEEECHHHCCHH
AFQRKCFARIQDIQERGGTILFVSHAASTVVQLCDSAILMDHGEMLLYHTPKYVVSKYQK
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCHHEECCCCEEEEECCHHHHHHHHH
LIYAFPDKIPSIREEIRQIPNLTIQDLFDDQNTDKSPSKSAINSENLDQYQIAQSIEYEE
HHHHCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHH
IYDPDMIPSNTIHYPDKGAKIIDPHIITLEGKRVNHLVNRREYYYTYRVKFINSTSKIRF
CCCCCCCCCCCEECCCCCCEEECCEEEEECCHHHHHHHCCCEEEEEEEEEEECCCCCCHH
GMLIKTLSGFELGGASLHGYTKSVEYIAAQQIVIVKFRFKCLLNPGVYFLNAGVVGMAND
HHHHHHHCCCCCCCCEECCHHHHHHHHHHCEEEEEEEEEEEEECCCEEEEECCEEEECCC
HLTYLSRCIDIAMFKVQHYSDSCGTGVIDFLIEPSLNIEHNTLNNKAKIESI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]