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The map label for this gene is yycF [H]

Identifier: 113474756

GI number: 113474756

Start: 1503514

End: 1504245

Strand: Reverse

Name: yycF [H]

Synonym: Tery_0954

Alternate gene names: 113474756

Gene position: 1504245-1503514 (Counterclockwise)

Preceding gene: 113474758

Following gene: 113474755

Centisome position: 19.41

GC content: 37.7

Gene sequence:

>732_bases
GTGGAATATAATAAAGAAAAAATCTTGGTTGTTGATGATGAAGCAAGTATTCGTCGTATTTTAGAAACTCGACTGTCAAT
GATTGGGTATGATGTTGTTACTGCTGCTGATGGTGAAGAAGCTTTGGAGACTTTTCACAATACAACCCCAGATCTGGTGG
TATTAGATGTGATGATGCCAAAATTAGATGGTTATGGTGTCTGCCAAGAATTACGCAAAGAATCAGATATTCCTATAATT
ATGCTAACTGCTTTGGGAGATGTTGCAGATAGAATTACAGGTCTAGAATTAGGTGCTGATGATTATGTGGTGAAGCCTTT
TTCTCCAAAAGAATTAGAAGCAAGAATTCGTTCTGTATTACGTCGGGTCGATAAAAATGGTGGTAATGGTATTCCTAGTT
CTGGTGTTATTCAAGTCAGCACTATTAGAATTGACACTAATAAACGTCAGGTTTATAAAGGTGATGAAAGAATTAGACTA
ACTGGTATGGAGTTTAGTTTATTAGAGTTATTGGTAAGTCGTTCTGGAGAGCCTTTTTCTCGTTCTGAGATTTTGCAGGA
AGTTTGGGGTTACACTCCAGAGCGTCATGTAGATACGCGAGTAGTGGATGTTCATATTTCTAGGCTTAGGGCTAAGTTGG
AAGAAGATCCAAGTAACCCAGAATTGATTTTAACTGCACGAGGCACTGGTTATCTATTTCAACGAATTATTGAACGTGAT
GAAGTTGGTTGA

Upstream 100 bases:

>100_bases
CTTAGGAGTAGTAAAAAATAGTAATTTTTGTTGTTATTTTGATGATACAGTTAAAAAAATTAATATAATTATAAACCTTA
GTTAAGGAGTGTGAGAAAAA

Downstream 100 bases:

>100_bases
AATATACAGGACTTATGTACCCAAACAAGAAACTAGGTCTATTGCCATAATTACTTCTCATAACCCGGTTTCTTTGTAAG
TCTTAATATAGTTAAAGTTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMPKLDGYGVCQELRKESDIPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERD
EVG

Sequences:

>Translated_243_residues
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMPKLDGYGVCQELRKESDIPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERD
EVG
>Mature_243_residues
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMPKLDGYGVCQELRKESDIPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERD
EVG

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=44.2553191489362, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.4347826086956, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=38.4279475982533, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=40.0881057268723, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=41.4529914529915, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=36.7521367521368, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=37.7682403433476, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.4978165938865, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.3144104803493, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=35.9307359307359, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.6283185840708, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=32.7510917030568, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=34.051724137931, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=37.9310344827586, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=36.2745098039216, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=35.5371900826446, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=38.2352941176471, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=37.1428571428571, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=107, Percent_Identity=33.6448598130841, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27403; Mature: 27403

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEHHHC
KLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVL
CCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHH
RRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEPFS
HHHHCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCEEEEECCHHHHHHHHHHCCCCCCC
RSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHC
EVG
CCC
>Mature Secondary Structure
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCEEEEEHHHC
KLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVL
CCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHH
RRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEPFS
HHHHCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCEEEEECCHHHHHHHHHHCCCCCCC
RSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHC
EVG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]