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The map label for this gene is ggt [H]

Identifier: 113474720

GI number: 113474720

Start: 1435656

End: 1437428

Strand: Direct

Name: ggt [H]

Synonym: Tery_0909

Alternate gene names: 113474720

Gene position: 1435656-1437428 (Clockwise)

Preceding gene: 113474719

Following gene: 113474722

Centisome position: 18.52

GC content: 41.74

Gene sequence:

>1773_bases
ATGCCTCAGATTCGATTCCCTCAAACTAAAAACCAAATAGTAATATTGAGTTGTGTCGCTGTTTTCTTATGGCTGTTTAG
CTGTACTCCCAACTCTCCAAAATCTCTACCTCTAGCAGAATTAAAACGGAGCAAAGAAAGTATAGTAGTTTCAGCTCATC
CCCTAGCTAGTGAAGCAGGAAAGTTAATGCTAGAAAAAGGGGGCAATGCAGTAGATGCAGCGGTAGCTACAGCCTTTGCT
ATTTCTGTAGTAGAACCATTTTCCGCAGGTATTGGAGGTGGAGGCTTTTTACTATTAGGAACTCCTCCAGAAAATTCTGA
GACTCAACAGTATAAAATTCGAGCCCTAGACTTTCGGGAAAGAGCTCCTAAAGCAGCAACTCGAAATATGTACCTTAACG
AAAAGGGAGAAGTAGAGAAAAGAGCAAGTTTAGATGGACATTTAGCAGTCGGAGTACCTGGAACCGTAGCAGGATTGTAT
AATATTCACAAGTCCTTAGGCAAGTTACCTTGGAAAGAATTGCTAAAACCAGCTATTCGTTATGCTCGTGATGGGTTTGA
GCTAAGGGATGACTTTGTTAGTAAACTAGAAAAACGCTTAGAGGTAATTAACAAAAATCCGGCAGCTAGGGATATATTTA
CTAAAAATGGCCAAGCTTATGAACCAGGAGATTTGCTGATTCAAACTGATCAAGCTCAAACCTTAGAAACCATTGCTGAA
AATCCTCAAAGCTTTTATACAGGTAAAATTGCTCAGGCGATCGCTACTGATATGGCCAAAGCAGGAGGTCTAATTACTTT
AGAAGATTTACAGAACTATACACCAATATGGCGTGAACCTATTTGTGGCAAGTTTAGACAAGCAAAAGTTTGTGCTATGC
CACCACCATCTTCTGGAGGCGTACATTTACTACAAATATTAAATATTGTGGGAGAGACTAACTTGCAACAGTGGGGTAGG
GAAAATGCTGATACTATTCATTTACTTACTGAAGCCATGCGGGTTGCTTATGCCGATCGCTCTTTGCATTTAGGGGACCC
AGATTTTCTGGAAGTGCCAGTCAAGGAGTTGACTAGCTTGAGTTATGCTCAACAACGACGTCAGGAAATTAGTCTCACAA
AAGTCAGACGTTCCACTGAAGTACAACCAGTATCACCAGAAGTTCTCAGGAGTAATATTTTGGAGTCTCCTGATACTACT
CATTTAACCGTAGTAGATCAAGAGCGAAATGTTATTAGTATGACATATACAATTAATGGTAGTTTTGGTGCTGGAGTGGT
AGCTGCTGGTACAGGAATATTGTTAAATAATGAAATGGATGATTTTGCCGCTGCTCCTGAAGCACCAAATTTATACGGTT
TGGTCGGGGATGAAGCGAATGCTATAGCTCCGAGAAAAACTCCTTTGTCTAGTATGACTCCTACTATTGTTACAGACAAT
GGTCGGTTAATTATGGCGACTGGTTCTCCTGGGGGTAGTACGATTATTACCACAGTTTTGCAGGTTATATTGAATGTGTT
AGAGTATAAAATGAATGTTGCTGAAGCTGTGTCGGCTCCACGTTTTCACCATCAATGGCTGCCAGATAAGTTAATCTTGG
AAACAGGGGGGTTTGGCGAGGCAACTGTGAATGAGTTGAAACAGCGCGGACATAATGTAGTAATGCAACGTGGTTGGGGT
AATGCAAATGTAGTTTTCCAGGATGAGAGTGGGATGTTGGAAGCAGCAGCAGATCCTCGTGGGGAAGGGGAGGCAATGGG
GACTGGCCAGTAG

Upstream 100 bases:

>100_bases
AATACTAAAGAAATAAATTTCGAGCGCGATCGCCTGAAGCGACGTTTTCAACCAAACTAAATTATTATGATAAATTTATG
TAAAACACTGTAGTTCCATT

Downstream 100 bases:

>100_bases
CTCACGAGGGTAGGTTTTTGATTTTCTGGTTGTTACAATATTTGGAAGCGTGGATATATAATACCAATTTTCTAAAGCCA
GACTACACATACCTTGACAT

Product: gamma-glutamyltransferase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MPQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAGKLMLEKGGNAVDAAVATAFA
ISVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRERAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLY
NIHKSLGKLPWKELLKPAIRYARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAE
NPQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGGVHLLQILNIVGETNLQQWGR
ENADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSLSYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTT
HLTVVDQERNVISMTYTINGSFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDN
GRLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGEATVNELKQRGHNVVMQRGWG
NANVVFQDESGMLEAAADPRGEGEAMGTGQ

Sequences:

>Translated_590_residues
MPQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAGKLMLEKGGNAVDAAVATAFA
ISVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRERAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLY
NIHKSLGKLPWKELLKPAIRYARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAE
NPQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGGVHLLQILNIVGETNLQQWGR
ENADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSLSYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTT
HLTVVDQERNVISMTYTINGSFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDN
GRLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGEATVNELKQRGHNVVMQRGWG
NANVVFQDESGMLEAAADPRGEGEAMGTGQ
>Mature_589_residues
PQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAGKLMLEKGGNAVDAAVATAFAI
SVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRERAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLYN
IHKSLGKLPWKELLKPAIRYARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAEN
PQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGGVHLLQILNIVGETNLQQWGRE
NADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSLSYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTTH
LTVVDQERNVISMTYTINGSFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDNG
RLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGEATVNELKQRGHNVVMQRGWGN
ANVVFQDESGMLEAAADPRGEGEAMGTGQ

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=546, Percent_Identity=34.981684981685, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI73915090, Length=546, Percent_Identity=34.981684981685, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI73915096, Length=546, Percent_Identity=34.981684981685, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI73915094, Length=546, Percent_Identity=34.981684981685, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI113429324, Length=546, Percent_Identity=34.2490842490842, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI113429326, Length=551, Percent_Identity=33.9382940108893, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI109148539, Length=523, Percent_Identity=30.7839388145315, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI153266885, Length=557, Percent_Identity=28.0071813285458, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI153266901, Length=558, Percent_Identity=27.9569892473118, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI153266907, Length=557, Percent_Identity=26.9299820466786, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI30581157, Length=233, Percent_Identity=35.1931330472103, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI30581155, Length=233, Percent_Identity=35.1931330472103, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI218505805, Length=233, Percent_Identity=32.1888412017167, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310124095, Length=237, Percent_Identity=31.2236286919831, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1789856, Length=542, Percent_Identity=45.5719557195572, Blast_Score=487, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17506189, Length=607, Percent_Identity=33.2784184514003, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI212646519, Length=511, Percent_Identity=33.8551859099804, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI72000294, Length=511, Percent_Identity=34.4422700587084, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17542894, Length=600, Percent_Identity=31.6666666666667, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI193208245, Length=565, Percent_Identity=31.1504424778761, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193208247, Length=565, Percent_Identity=31.1504424778761, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17564448, Length=460, Percent_Identity=25.8695652173913, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI72001497, Length=234, Percent_Identity=31.1965811965812, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI72001495, Length=234, Percent_Identity=31.1965811965812, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323330, Length=516, Percent_Identity=29.8449612403101, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24642670, Length=507, Percent_Identity=31.9526627218935, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24642666, Length=507, Percent_Identity=31.9526627218935, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI161077880, Length=507, Percent_Identity=31.9526627218935, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI45551474, Length=507, Percent_Identity=31.9526627218935, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI161077878, Length=507, Percent_Identity=31.9526627218935, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI18859893, Length=523, Percent_Identity=32.1223709369025, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI161077496, Length=513, Percent_Identity=31.9688109161793, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859741, Length=520, Percent_Identity=30.3846153846154, Blast_Score=196, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 64043; Mature: 63912

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAG
CCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEECCCHHHHH
KLMLEKGGNAVDAAVATAFAISVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRE
HEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECHHH
RAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLYNIHKSLGKLPWKELLKPAIR
HCCCHHHHCCEECCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
YARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAE
HHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHC
NPQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGG
CCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCC
VHLLQILNIVGETNLQQWGRENADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSL
HHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCHHHCCHHHHHHH
SYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTTHLTVVDQERNVISMTYTING
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECC
SFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDN
CCCCCCEECCCEEEECCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECC
GRLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGE
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCH
ATVNELKQRGHNVVMQRGWGNANVVFQDESGMLEAAADPRGEGEAMGTGQ
HHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAG
CCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEECCCHHHHH
KLMLEKGGNAVDAAVATAFAISVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRE
HEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECHHH
RAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLYNIHKSLGKLPWKELLKPAIR
HCCCHHHHCCEECCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
YARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAE
HHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHC
NPQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGG
CCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCC
VHLLQILNIVGETNLQQWGRENADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSL
HHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCHHHCCHHHHHHH
SYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTTHLTVVDQERNVISMTYTING
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECC
SFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDN
CCCCCCEECCCEEEECCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECC
GRLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGE
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCH
ATVNELKQRGHNVVMQRGWGNANVVFQDESGMLEAAADPRGEGEAMGTGQ
HHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]