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The map label for this gene is pbpG [H]

Identifier: 113474315

GI number: 113474315

Start: 698789

End: 700753

Strand: Reverse

Name: pbpG [H]

Synonym: Tery_0444

Alternate gene names: 113474315

Gene position: 700753-698789 (Counterclockwise)

Preceding gene: 113474318

Following gene: 113474311

Centisome position: 9.04

GC content: 41.02

Gene sequence:

>1965_bases
ATGAAGTCTATCCAAGGAAGTGAAATCAAAGTGTCCACCAACACTCTCCCAAACAAGCAAACTAAAAAACCATTATCTAA
ATCTGCACCAGTCTTCGAGTTTGTTCAGTCTGTCGGTAAAGTTACAACAGGTACAGTATTAGGCATTACTATGCTGACTA
GCTCATTAGTTGCTGGTGGATTAGTAGGTTTAGCCATTAGCTTTCGTAATCTGCCAGATGTAAGGCTGCTCAAAAATTAT
ACACCTTCAGAAACAACTCGTATATATGATATCAAAGGTAGGCCCCTGGCAAGTCTCCATGATGAGGCCAACCGAGAAGT
CATGCCTCTAAAGCAAATTTCTCCAGACCTCAAACGAGCAGTTTTGGCAATCGAAGATAGTAATTTCTACAATCACCTAG
GGATTTATCCCATTGGAATTATGCGTGCTCTTGTAGCTAACTTAGAGCGGGGTAAAACCGTTGAAGGTGGTTCTACTGTG
ACCATGCAATTGGTAAAAAATTTGTTTCTCTCCCCAACAGCCAAACTTAGTAGGAAAGTAGCTGAAGCAGTTTTGGCAAT
TAGAATGGAACAAATTATGGCCAAAGATGAAATTTTAGAATTATACCTCAACCAAATTTACTGGGGCCATAATTTATATG
GAGTTGAAACTGCAGCTCGAAGCTATTTTAATAAGTCTTCCGAAGATTTAACCTTGGCGGAAGCGGCCTTGATGGCAGGT
ATGATTCCTGCGCCAGAGGAATATAGCCCTTTTATTAACTACAAAAAGTCTAAACAGCGTCAGGCAACAGTTCTAGCCAG
GATGCGAGAACTAAATTGGATTACCGCTCAAGAGGAAGCAGAAGCTCTCAAACAACCATTGTATGTAGGTAAAGTTACTT
CTTTTGGTAAGAGTAAACTTCCTTATATTACCAGTGCAGTTATTCAGGAATTAACTGAGAGGTTCGGTAAAGATGCTGTT
CTGAAGGGAGGAATGCGCATACAAACTACTATTGATATGAACTTCCAAAAGATGGCAGAGAAAACTGTAAGTGAATGGCA
TAAAATCTTATATTATCGTGGGCTTTATCGGAGTTGGGACAAAGGTCAATTAGCATTAGTAGCAGTTGACCCACGCACTC
ATTTTGTCAAAGCGATGGTTGGTGGGGCAGATTTTAAAACAAGTCAATATAATCGCGCTGTTCAAGCTTTCAGGCAACCT
GGTTCTTCGTTTAAACCTTTTGTTTACTATACTGCTTTTGCTTCGGGTAGATTTACCCCATCTTCAGTGGTTATAGATGC
TCCTGTTAATTATCGAGATGGTACCGGTTATTATTCTCCTCGAAATTATGGTGGCGGATATTCTGGAGCAGTAAGTATTC
GTAAGGCTTTACAATCTTCTCTGAACATACCTGCTGTTAAAATTGGTCAGGTTGTAGGGCTTAATAAGGTGATTGAGGTT
TGTCGAATCTTGGGAATTAAAAGTCCCATGGAACCCGTGATTTCTTTACCATTGGGTTCTGTTGACTTGACACCTCTAGA
AATGGCGGGTGCCTATGCCACTTTTGCTAATAATGGCTGGCATTCTGATACGACGTTTATTGTCCAGGTGACAGATACTA
GTGGAAATGTCTTATTGGACAATACTCCTAAACCTAAATTGGTTCTCAATCAGTGGGCTGTAGCATCACTTAATAGTATA
TTGGTGGGAGTAATTGAACAAGGTACGGCTACTAGGGCGAGAATAAGTCGTCAAGCTGCTGGAAAAACTGGTACGACTTC
TTCAGAAAGGGATGTTTGGTTTGTTGGCTATACTCCTCAGTTGTCAACTGCCGTTTGGGTAGGTAACGATGATTACCGAC
CACTCAACTATGGAGCTACTGGTGGTACTACTGTTGCACCTATCTGGCGTGATTTTATGAATCAAGCCATGAGTGGTATG
CGCAAAGAATATTTTCCTCCGGCATATAAGTTTGATAGGCCCTAG

Upstream 100 bases:

>100_bases
TCAGTCATCATCTAGTCTTAATGAATATATACAGCTTAACTCTGAGGGTCATTTCAGTTATTAGTCTTCTCTGAGAAGTC
TAATTATACTGATCAAAAAT

Downstream 100 bases:

>100_bases
TGTTTTTGTATTGAATTAGTTCAGTAGAGATATGTTATCGGTACTTTAAGATTTAAATTAAATACATCAAAAATAACCTC
AAACCAAGTCCAGTTAAATC

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MKSIQGSEIKVSTNTLPNKQTKKPLSKSAPVFEFVQSVGKVTTGTVLGITMLTSSLVAGGLVGLAISFRNLPDVRLLKNY
TPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRAVLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTV
TMQLVKNLFLSPTAKLSRKVAEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAG
MIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKLPYITSAVIQELTERFGKDAV
LKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWDKGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQP
GSSFKPFVYYTAFASGRFTPSSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEV
CRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLDNTPKPKLVLNQWAVASLNSI
LVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQLSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGM
RKEYFPPAYKFDRP

Sequences:

>Translated_654_residues
MKSIQGSEIKVSTNTLPNKQTKKPLSKSAPVFEFVQSVGKVTTGTVLGITMLTSSLVAGGLVGLAISFRNLPDVRLLKNY
TPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRAVLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTV
TMQLVKNLFLSPTAKLSRKVAEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAG
MIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKLPYITSAVIQELTERFGKDAV
LKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWDKGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQP
GSSFKPFVYYTAFASGRFTPSSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEV
CRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLDNTPKPKLVLNQWAVASLNSI
LVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQLSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGM
RKEYFPPAYKFDRP
>Mature_654_residues
MKSIQGSEIKVSTNTLPNKQTKKPLSKSAPVFEFVQSVGKVTTGTVLGITMLTSSLVAGGLVGLAISFRNLPDVRLLKNY
TPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRAVLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTV
TMQLVKNLFLSPTAKLSRKVAEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAG
MIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKLPYITSAVIQELTERFGKDAV
LKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWDKGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQP
GSSFKPFVYYTAFASGRFTPSSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEV
CRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLDNTPKPKLVLNQWAVASLNSI
LVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQLSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGM
RKEYFPPAYKFDRP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=528, Percent_Identity=35.2272727272727, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI87082258, Length=289, Percent_Identity=39.4463667820069, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788867, Length=550, Percent_Identity=27.4545454545455, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI1789601, Length=169, Percent_Identity=36.6863905325444, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 72146; Mature: 72146

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIQGSEIKVSTNTLPNKQTKKPLSKSAPVFEFVQSVGKVTTGTVLGITMLTSSLVAGG
CCCCCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHH
LVGLAISFRNLPDVRLLKNYTPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRA
HHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHCCHHHHHE
VLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTVTMQLVKNLFLSPTAKLSRKV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHH
AEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHC
MIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCCCCCCC
PYITSAVIQELTERFGKDAVLKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWD
CHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQPGSSFKPFVYYTAFASGRFTP
CCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCC
SSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEV
CCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHH
CRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLD
HHHHCCCCCCHHHHCCCCCCCCCCHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCEEEC
NTPKPKLVLNQWAVASLNSILVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQ
CCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
LSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGMRKEYFPPAYKFDRP
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKSIQGSEIKVSTNTLPNKQTKKPLSKSAPVFEFVQSVGKVTTGTVLGITMLTSSLVAGG
CCCCCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHH
LVGLAISFRNLPDVRLLKNYTPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRA
HHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHCCHHHHHE
VLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTVTMQLVKNLFLSPTAKLSRKV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHH
AEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHC
MIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCCCCCCC
PYITSAVIQELTERFGKDAVLKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWD
CHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQPGSSFKPFVYYTAFASGRFTP
CCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCC
SSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEV
CCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHH
CRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLD
HHHHCCCCCCHHHHCCCCCCCCCCHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCEEEC
NTPKPKLVLNQWAVASLNSILVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQ
CCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
LSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGMRKEYFPPAYKFDRP
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]