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The map label for this gene is ubiE [H]

Identifier: 113474245

GI number: 113474245

Start: 562495

End: 563130

Strand: Reverse

Name: ubiE [H]

Synonym: Tery_0364

Alternate gene names: 113474245

Gene position: 563130-562495 (Counterclockwise)

Preceding gene: 113474250

Following gene: 113474243

Centisome position: 7.27

GC content: 33.33

Gene sequence:

>636_bases
ATGAGCGAATTTAAAATCCAAAAACAATATGATCAAATTGCTAATATTTATGATTGGCGCTGGCAAAGTTATATCATGAA
TACTCTGAGTTTTCTTCACACTTGGGAACAAATTGATCCACAGGCAAAGATTCTAGATGTTGCTTGTGGTACTGGGGAAT
TTGAACGACTCTTGCTCAAAAAAAATCCGACACAGAGAATTATCGGAATTGATATATCTGAGAAGATGTTAAATATAGCT
AGGAAAAAATATCAAACTAATTCTAATGTCGAGTTTCAAAAAGTTTCAGTTCATTCACTACCGTTTAACAGTCATTCTTT
TGATGTGGTTGTATGTGCTAATGCTTTTCATTATTTTGACTATCCTCAAGTAGCATTAGGAGAAATTAAACGGGTGCTTA
AACCCAGTGGCAAAGTAATAATTCTTGACTGGAACAAAGATTATTTTTTTTGCAGAATATGCGACTGGTTCTTACGAATT
TTCGATTCTGCTCATCAACAATGCTATACTCAAGCTGAATTACATCAGTTATTGGTATCTGCTGAGTTTAAAATACATAA
TGCAACTAAATTTCGTTTAGGATTTATTTGGGGACTGATGGTTGTTACAGCTATACCTATAAAATCCTATGCTTAG

Upstream 100 bases:

>100_bases
CCTATTTTTTTCGTAGGATTAAAATATCCTATTGACTATTTTTTTATCCTCTGGGTTTAGCTGATTTTCCTAATAACTGA
TAATTGATAACTGAAATGAT

Downstream 100 bases:

>100_bases
GTGATTTTAAATTTATTTATCTTTGTAAATTAAAGTAAACTTACTCTTAAATTTTACAAAAAAAGTTAGACAAAAATTTT
TTATACCGAAAATATAGTTA

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSEFKIQKQYDQIANIYDWRWQSYIMNTLSFLHTWEQIDPQAKILDVACGTGEFERLLLKKNPTQRIIGIDISEKMLNIA
RKKYQTNSNVEFQKVSVHSLPFNSHSFDVVVCANAFHYFDYPQVALGEIKRVLKPSGKVIILDWNKDYFFCRICDWFLRI
FDSAHQQCYTQAELHQLLVSAEFKIHNATKFRLGFIWGLMVVTAIPIKSYA

Sequences:

>Translated_211_residues
MSEFKIQKQYDQIANIYDWRWQSYIMNTLSFLHTWEQIDPQAKILDVACGTGEFERLLLKKNPTQRIIGIDISEKMLNIA
RKKYQTNSNVEFQKVSVHSLPFNSHSFDVVVCANAFHYFDYPQVALGEIKRVLKPSGKVIILDWNKDYFFCRICDWFLRI
FDSAHQQCYTQAELHQLLVSAEFKIHNATKFRLGFIWGLMVVTAIPIKSYA
>Mature_210_residues
SEFKIQKQYDQIANIYDWRWQSYIMNTLSFLHTWEQIDPQAKILDVACGTGEFERLLLKKNPTQRIIGIDISEKMLNIAR
KKYQTNSNVEFQKVSVHSLPFNSHSFDVVVCANAFHYFDYPQVALGEIKRVLKPSGKVIILDWNKDYFFCRICDWFLRIF
DSAHQQCYTQAELHQLLVSAEFKIHNATKFRLGFIWGLMVVTAIPIKSYA

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17557039, Length=131, Percent_Identity=25.9541984732824, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 24798; Mature: 24667

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFKIQKQYDQIANIYDWRWQSYIMNTLSFLHTWEQIDPQAKILDVACGTGEFERLLLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHC
KNPTQRIIGIDISEKMLNIARKKYQTNSNVEFQKVSVHSLPFNSHSFDVVVCANAFHYFD
CCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCEEEEEEECHHHHCC
YPQVALGEIKRVLKPSGKVIILDWNKDYFFCRICDWFLRIFDSAHQQCYTQAELHQLLVS
CCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFKIHNATKFRLGFIWGLMVVTAIPIKSYA
HHEEECCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEFKIQKQYDQIANIYDWRWQSYIMNTLSFLHTWEQIDPQAKILDVACGTGEFERLLLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHC
KNPTQRIIGIDISEKMLNIARKKYQTNSNVEFQKVSVHSLPFNSHSFDVVVCANAFHYFD
CCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCEEEEEEECHHHHCC
YPQVALGEIKRVLKPSGKVIILDWNKDYFFCRICDWFLRIFDSAHQQCYTQAELHQLLVS
CCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFKIHNATKFRLGFIWGLMVVTAIPIKSYA
HHEEECCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA