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The map label for this gene is 113474250

Identifier: 113474250

GI number: 113474250

Start: 568161

End: 568865

Strand: Reverse

Name: 113474250

Synonym: Tery_0369

Alternate gene names: NA

Gene position: 568865-568161 (Counterclockwise)

Preceding gene: 113474251

Following gene: 113474245

Centisome position: 7.34

GC content: 35.46

Gene sequence:

>705_bases
ATGTTGCTTCAAGACAAACAAATGACTGCACAAGATTTCATGTCCTTACTGGATGAGATTATTGAAAAACAACATTTACT
TAAGCACACATTCTACCAAATGTGGAATCAAGGAAAATTATCTTTAAAAATGTTGCAGGAGTACGCTCAGGAATATTATC
TACAAGTTCATTATTTCCCTACTTATATTAGCGCTACTCATGCAGCTTGTGATGATTTAGAAATTCGTAAAATGCTCTTA
GAAAATCTGATTGAAGAAGAAATGGGAGCAGCAAATCACCCTGAGTTATGGTTACGTTTTGCTGAAGGTTTGGATGTAAA
AAGAGAAGCAGTTAAAGAGCGGGAACATTTAGCAAAAACCAAGAAATCTGTAAGTATTCTCAAGGAATTAGCTGGGAGTG
AAAACCCGGCTAAAGGTTTAGCTGCTCTTTATGCTTATGAATCACAAATTCCTGAGGTTGCTAGTACTAAAATTGCTGGT
TTAAAAGAATTTTATGGGATTAATTCTGAAGCAGCTCTATCATTTTTTAAAGTACATGAAAAAGCTGATGAAATTCACAG
CAAAGTCACAAAAGAAGCATTAGTAAAACTATGTGAAACTGATGCTCAGAAAGAGGAAGCGTTGGCAGCAGCAGCAACAG
CGGTGGATGCTTTGAATTTATTGCTTGATGGTGTTTATGAAGAATATTGTCAAGCTGTGAATTAA

Upstream 100 bases:

>100_bases
TCTAAATTGAGTTTATAAAAAAAATATTTTATATTCTTGACAAACCAGAAAGTTGTGTTATTTTAGCATTGATATTTAAT
ATTTAGTTAAGCGAATAAGT

Downstream 100 bases:

>100_bases
TGGTTAATTAACATGTTGAATAATTAGCTTACTAAACAGAGACTAGAGGTTTTGTATATCTACTTCTAGTCTCTATTAGA
CCATTATACCAGTTTTTCTG

Product: TENA/THI-4 protein

Products: NA

Alternate protein names: Chlamydia protein associating with death domains; CADD [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLLQDKQMTAQDFMSLLDEIIEKQHLLKHTFYQMWNQGKLSLKMLQEYAQEYYLQVHYFPTYISATHAACDDLEIRKMLL
ENLIEEEMGAANHPELWLRFAEGLDVKREAVKEREHLAKTKKSVSILKELAGSENPAKGLAALYAYESQIPEVASTKIAG
LKEFYGINSEAALSFFKVHEKADEIHSKVTKEALVKLCETDAQKEEALAAAATAVDALNLLLDGVYEEYCQAVN

Sequences:

>Translated_234_residues
MLLQDKQMTAQDFMSLLDEIIEKQHLLKHTFYQMWNQGKLSLKMLQEYAQEYYLQVHYFPTYISATHAACDDLEIRKMLL
ENLIEEEMGAANHPELWLRFAEGLDVKREAVKEREHLAKTKKSVSILKELAGSENPAKGLAALYAYESQIPEVASTKIAG
LKEFYGINSEAALSFFKVHEKADEIHSKVTKEALVKLCETDAQKEEALAAAATAVDALNLLLDGVYEEYCQAVN
>Mature_234_residues
MLLQDKQMTAQDFMSLLDEIIEKQHLLKHTFYQMWNQGKLSLKMLQEYAQEYYLQVHYFPTYISATHAACDDLEIRKMLL
ENLIEEEMGAANHPELWLRFAEGLDVKREAVKEREHLAKTKKSVSILKELAGSENPAKGLAALYAYESQIPEVASTKIAG
LKEFYGINSEAALSFFKVHEKADEIHSKVTKEALVKLCETDAQKEEALAAAATAVDALNLLLDGVYEEYCQAVN

Specific function: Chlamydia specific toxin inducing apoptosis in mammalian cell lines [H]

COG id: COG5424

COG function: function code H; Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C

Gene ontology:

Cell location: Secreted. Note=Secreted into the host cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pqqC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: NA

Molecular weight: Translated: 26535; Mature: 26535

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQDKQMTAQDFMSLLDEIIEKQHLLKHTFYQMWNQGKLSLKMLQEYAQEYYLQVHYFP
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TYISATHAACDDLEIRKMLLENLIEEEMGAANHPELWLRFAEGLDVKREAVKEREHLAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
KKSVSILKELAGSENPAKGLAALYAYESQIPEVASTKIAGLKEFYGINSEAALSFFKVHE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KADEIHSKVTKEALVKLCETDAQKEEALAAAATAVDALNLLLDGVYEEYCQAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLQDKQMTAQDFMSLLDEIIEKQHLLKHTFYQMWNQGKLSLKMLQEYAQEYYLQVHYFP
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TYISATHAACDDLEIRKMLLENLIEEEMGAANHPELWLRFAEGLDVKREAVKEREHLAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
KKSVSILKELAGSENPAKGLAALYAYESQIPEVASTKIAGLKEFYGINSEAALSFFKVHE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KADEIHSKVTKEALVKLCETDAQKEEALAAAATAVDALNLLLDGVYEEYCQAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]