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The map label for this gene is cobL [H]

Identifier: 113474111

GI number: 113474111

Start: 317874

End: 319187

Strand: Reverse

Name: cobL [H]

Synonym: Tery_0210

Alternate gene names: 113474111

Gene position: 319187-317874 (Counterclockwise)

Preceding gene: 113474112

Following gene: 113474109

Centisome position: 4.12

GC content: 37.67

Gene sequence:

>1314_bases
GTGAAAAAACTAGCTCCAGAACTCAGGGAAAAGCAGGGAAAAAACATAATTATTGTGACTATAAATGTTATTGGTATAGG
TTTAGATGGAGTAGTTGGACTAAATCAGTTAGTACGAGAAATTGTTAAAAGAGCGACTTTGTTGGTAGGAAGCGATCGCC
ATCTCAGTTATTTTTCTGATAATAACGCTGAAAGTATTGTAATTAAAGATCTACTTGAGGCAATTTTAGAAATACGACAG
CATTTAGAGACTCCTAATAGTTGTATAGTGGTTTTAGCTTCAGGAGATCCCCTATTTTTTGGTTTAGGGAGGTTATTAGT
AGCACATTTTCCTGCAGAAAAATTAAGGTTTTACCCCCATCTGAGTTCGGTACAATTAGCTTTTAGCCGGATCAAAGTTC
CTTGGCAAGATACTAAAATAATTAGTGTTCATGGTCGTCCTATGGATGAGCTGATTAAAGCATTACAGCAAGGAGCTGAG
AAGGTTGCTGTACTCACAGACCCGACCAATACACCACAAGCGATCGCTAATTTGCTACTATCTTTACATCTGCCAGCTAC
ATATCAATTTTGGGTATGTGAAAATCTTGGTGCTGAGGATGAACGAGTCCAACAATGGTCTATAGATGAAATACAAAAAG
AAACATTTGCACCATTGAATTTGGTGGTATTGTTGCGTAAAGCTAGAATGGCTAATCAACCTGTAGATTTAGTTGATTTA
CCTCTTTTGGGGATACCAGATAATTATTTTTTAAGTTATGATGACCATCCAGGCTTGATGAGTAAGCGGGAAGTCCGGGT
GTTAATTTTAGCTGAGTTGAGTTTGCAACCAGGACAAATAATATGGGATATTGGTGCTGGTACCGGTTCTGTTGCAGTGG
AAATTGCTCGCCTTTGCAGTAGTTCTATAGTATATGCAATTGAAAAAACTGCTATAGGAACAAGTTTAATTGAAGAAAAT
TGTCGTCGCTTTCAACTAAAAAATGTCGTTTCTCTTCATGGTAATGCTCCGGAAATTTTGCATCATCTACGTCCTCCCCA
CAGAGTTTTTATAGGGGGTAGTAGTGGTAAACTCAGAAATATTCTGGGAGTTTGTGGAATTAGAATGTTGCCTGAAGGGG
TAATAGTTTTAGCATTTACAACTTTGGAAAATTTGCATACTGCTATAAGTTGGGTAGAAGAGAGAAGAAGGAGCGATCGC
TCTTGGAGTTATCGTCTTTTGCAAGTGCAGTTATCTCGTTCTATACCTGTAGCTAATTTAACTCGATTTAATCCTCTTAA
TCCTGTCACAATTATGATCGTTAAACGGGATTAA

Upstream 100 bases:

>100_bases
CATTGAAATGTTATAACCAGTAAGGTTTTATATCAGTTTTCTTGTATGAGGTTAAGATTTAATATCCGATTAAACTGTTG
TAAATTCTATTCTGGTTATA

Downstream 100 bases:

>100_bases
AATTATGTCTGCACCTTAAATGGGTTGTGTTATATAATTTTTTTTCAAGTAGGTAGCTACAAAAAAGCTTAACTATATTA
AATTTTGTCAAGCAACTCTA

Product: precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKKLAPELREKQGKNIIIVTINVIGIGLDGVVGLNQLVREIVKRATLLVGSDRHLSYFSDNNAESIVIKDLLEAILEIRQ
HLETPNSCIVVLASGDPLFFGLGRLLVAHFPAEKLRFYPHLSSVQLAFSRIKVPWQDTKIISVHGRPMDELIKALQQGAE
KVAVLTDPTNTPQAIANLLLSLHLPATYQFWVCENLGAEDERVQQWSIDEIQKETFAPLNLVVLLRKARMANQPVDLVDL
PLLGIPDNYFLSYDDHPGLMSKREVRVLILAELSLQPGQIIWDIGAGTGSVAVEIARLCSSSIVYAIEKTAIGTSLIEEN
CRRFQLKNVVSLHGNAPEILHHLRPPHRVFIGGSSGKLRNILGVCGIRMLPEGVIVLAFTTLENLHTAISWVEERRRSDR
SWSYRLLQVQLSRSIPVANLTRFNPLNPVTIMIVKRD

Sequences:

>Translated_437_residues
MKKLAPELREKQGKNIIIVTINVIGIGLDGVVGLNQLVREIVKRATLLVGSDRHLSYFSDNNAESIVIKDLLEAILEIRQ
HLETPNSCIVVLASGDPLFFGLGRLLVAHFPAEKLRFYPHLSSVQLAFSRIKVPWQDTKIISVHGRPMDELIKALQQGAE
KVAVLTDPTNTPQAIANLLLSLHLPATYQFWVCENLGAEDERVQQWSIDEIQKETFAPLNLVVLLRKARMANQPVDLVDL
PLLGIPDNYFLSYDDHPGLMSKREVRVLILAELSLQPGQIIWDIGAGTGSVAVEIARLCSSSIVYAIEKTAIGTSLIEEN
CRRFQLKNVVSLHGNAPEILHHLRPPHRVFIGGSSGKLRNILGVCGIRMLPEGVIVLAFTTLENLHTAISWVEERRRSDR
SWSYRLLQVQLSRSIPVANLTRFNPLNPVTIMIVKRD
>Mature_437_residues
MKKLAPELREKQGKNIIIVTINVIGIGLDGVVGLNQLVREIVKRATLLVGSDRHLSYFSDNNAESIVIKDLLEAILEIRQ
HLETPNSCIVVLASGDPLFFGLGRLLVAHFPAEKLRFYPHLSSVQLAFSRIKVPWQDTKIISVHGRPMDELIKALQQGAE
KVAVLTDPTNTPQAIANLLLSLHLPATYQFWVCENLGAEDERVQQWSIDEIQKETFAPLNLVVLLRKARMANQPVDLVDL
PLLGIPDNYFLSYDDHPGLMSKREVRVLILAELSLQPGQIIWDIGAGTGSVAVEIARLCSSSIVYAIEKTAIGTSLIEEN
CRRFQLKNVVSLHGNAPEILHHLRPPHRVFIGGSSGKLRNILGVCGIRMLPEGVIVLAFTTLENLHTAISWVEERRRSDR
SWSYRLLQVQLSRSIPVANLTRFNPLNPVTIMIVKRD

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 48802; Mature: 48802

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLAPELREKQGKNIIIVTINVIGIGLDGVVGLNQLVREIVKRATLLVGSDRHLSYFSD
CCCCCHHHHHHCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCEEEECC
NNAESIVIKDLLEAILEIRQHLETPNSCIVVLASGDPLFFGLGRLLVAHFPAEKLRFYPH
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHEECCC
LSSVQLAFSRIKVPWQDTKIISVHGRPMDELIKALQQGAEKVAVLTDPTNTPQAIANLLL
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
SLHLPATYQFWVCENLGAEDERVQQWSIDEIQKETFAPLNLVVLLRKARMANQPVDLVDL
HHCCCCEEEEEEECCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEC
PLLGIPDNYFLSYDDHPGLMSKREVRVLILAELSLQPGQIIWDIGAGTGSVAVEIARLCS
CEECCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHC
SSIVYAIEKTAIGTSLIEENCRRFQLKNVVSLHGNAPEILHHLRPPHRVFIGGSSGKLRN
CHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCHHHH
ILGVCGIRMLPEGVIVLAFTTLENLHTAISWVEERRRSDRSWSYRLLQVQLSRSIPVANL
HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC
TRFNPLNPVTIMIVKRD
CCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKKLAPELREKQGKNIIIVTINVIGIGLDGVVGLNQLVREIVKRATLLVGSDRHLSYFSD
CCCCCHHHHHHCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCEEEECC
NNAESIVIKDLLEAILEIRQHLETPNSCIVVLASGDPLFFGLGRLLVAHFPAEKLRFYPH
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHEECCC
LSSVQLAFSRIKVPWQDTKIISVHGRPMDELIKALQQGAEKVAVLTDPTNTPQAIANLLL
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
SLHLPATYQFWVCENLGAEDERVQQWSIDEIQKETFAPLNLVVLLRKARMANQPVDLVDL
HHCCCCEEEEEEECCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEC
PLLGIPDNYFLSYDDHPGLMSKREVRVLILAELSLQPGQIIWDIGAGTGSVAVEIARLCS
CEECCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHC
SSIVYAIEKTAIGTSLIEENCRRFQLKNVVSLHGNAPEILHHLRPPHRVFIGGSSGKLRN
CHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCHHHH
ILGVCGIRMLPEGVIVLAFTTLENLHTAISWVEERRRSDRSWSYRLLQVQLSRSIPVANL
HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC
TRFNPLNPVTIMIVKRD
CCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]