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The map label for this gene is cofG

Identifier: 113474077

GI number: 113474077

Start: 258358

End: 259317

Strand: Direct

Name: cofG

Synonym: Tery_0173

Alternate gene names: 113474077

Gene position: 258358-259317 (Clockwise)

Preceding gene: 113474075

Following gene: 113474078

Centisome position: 3.33

GC content: 31.98

Gene sequence:

>960_bases
ATGTCTAGAATTGTTACTTATAGTCCAGCTTATACAATAGTTCCTACTTATGAGTGTTTTAATAATTGCAGCTATTGTAA
TTTTCGCTCAGACCCCGGTAAAAGTTCTTGGTTGAGTCTATCAGAAGCAGAAAAACAATTATTATCTCTCAAAAATAAAG
GTACAATTGAAATATTAACTCTAAGTGGTGAAGTTCACCCGAATAGCAAATACAGAAAAGCTTGGTTTCAACTAATATAT
AAATTATGTCAACTAGCTCTATCTTTAGGATTTTTACCCCATACTAATGTAGGGATACTTACTAGGTCAGAAATGGAGGA
GTTGAAACAGGTAAATGTTTCAATGGGATTAATGTTGGAACAGATAACACCTAAATTACTAAAAATAGTCCATAAAAATT
CTCCTAGTAAAATACCACACTTACGTTTACAACAATTAGAATGGGCTGGGGAATTAAGAATTCCTTTTACTACTGGTTTA
TTGTTAGGAATTGGAGAGACTGTAACTGACTGGAAAGATACTTTAGAAGCAATTTCTAATATTCATCAAAAATGGGGTCA
TATTCAAGAAGTTATTATACAGCCATATAGTCCTGGTTCGGAAAATAAATGGGTTTCTGATGGTTTTAATGTCAATTTAT
TGCCAGAAGTTATAGCGATCGCTAATGAAGTTTTACCCTCAAATATTACTCTACAAATTCCTCCTAATTTAGTGAAAAAG
CCAGAAATATTATTGGCTTGTTTGGAAAATGGTGCCCGAGATTTAGGAGGGATAGGACCTTTTGATGAAATTAATCCTGA
TTATCCTCATCCTCACTATCAAGCTTTAATAAAAGTTTTGGAGTCTAGAGGATGGCAGTTAACTAAAAGATTACCAGTCT
ATTCTAAATATGATGATTGGTTACCAATAAATTTAAAAAATATTGTAAGTGAATGGCGTATAAAATTATCTATATATTGA

Upstream 100 bases:

>100_bases
CAAGTTTATTGAAAAAAAATCAGAATATATTCTTTCATTATTGCTCTTCTAACTGACTCATTTTTTAAAAGTTATATAAC
TAAAATTTAATCCTTTACCC

Downstream 100 bases:

>100_bases
TAGTTTTTAATTTGTTTAAAAGTGGAAATAATTAAGTTTTGCTTGAACTTTCTTCTTTAAAGGCAGGAAATTAGGACGGG
TGAAGCTAAATCTTGATTTT

Product: FO synthase subunit 1

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSRIVTYSPAYTIVPTYECFNNCSYCNFRSDPGKSSWLSLSEAEKQLLSLKNKGTIEILTLSGEVHPNSKYRKAWFQLIY
KLCQLALSLGFLPHTNVGILTRSEMEELKQVNVSMGLMLEQITPKLLKIVHKNSPSKIPHLRLQQLEWAGELRIPFTTGL
LLGIGETVTDWKDTLEAISNIHQKWGHIQEVIIQPYSPGSENKWVSDGFNVNLLPEVIAIANEVLPSNITLQIPPNLVKK
PEILLACLENGARDLGGIGPFDEINPDYPHPHYQALIKVLESRGWQLTKRLPVYSKYDDWLPINLKNIVSEWRIKLSIY

Sequences:

>Translated_319_residues
MSRIVTYSPAYTIVPTYECFNNCSYCNFRSDPGKSSWLSLSEAEKQLLSLKNKGTIEILTLSGEVHPNSKYRKAWFQLIY
KLCQLALSLGFLPHTNVGILTRSEMEELKQVNVSMGLMLEQITPKLLKIVHKNSPSKIPHLRLQQLEWAGELRIPFTTGL
LLGIGETVTDWKDTLEAISNIHQKWGHIQEVIIQPYSPGSENKWVSDGFNVNLLPEVIAIANEVLPSNITLQIPPNLVKK
PEILLACLENGARDLGGIGPFDEINPDYPHPHYQALIKVLESRGWQLTKRLPVYSKYDDWLPINLKNIVSEWRIKLSIY
>Mature_318_residues
SRIVTYSPAYTIVPTYECFNNCSYCNFRSDPGKSSWLSLSEAEKQLLSLKNKGTIEILTLSGEVHPNSKYRKAWFQLIYK
LCQLALSLGFLPHTNVGILTRSEMEELKQVNVSMGLMLEQITPKLLKIVHKNSPSKIPHLRLQQLEWAGELRIPFTTGLL
LGIGETVTDWKDTLEAISNIHQKWGHIQEVIIQPYSPGSENKWVSDGFNVNLLPEVIAIANEVLPSNITLQIPPNLVKKP
EILLACLENGARDLGGIGPFDEINPDYPHPHYQALIKVLESRGWQLTKRLPVYSKYDDWLPINLKNIVSEWRIKLSIY

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO)

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. CofG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFG_TRIEI (Q11A09)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720138.1
- STRING:   Q11A09
- GeneID:   4242923
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0173
- NMPDR:   fig|203124.1.peg.1705
- eggNOG:   COG1060
- HOGENOM:   HBG321713
- OMA:   PTYECFN
- ProtClustDB:   PRK06245
- BioCyc:   TERY203124:TERY_0173-MONOMER
- HAMAP:   MF_01611
- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR019939
- InterPro:   IPR007197
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00729
- TIGRFAMs:   TIGR03550

Pfam domain/function: PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 36270; Mature: 36139

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIVTYSPAYTIVPTYECFNNCSYCNFRSDPGKSSWLSLSEAEKQLLSLKNKGTIEILT
CCCEEEECCCEEEEECHHHHCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHCCCCCEEEEE
LSGEVHPNSKYRKAWFQLIYKLCQLALSLGFLPHTNVGILTRSEMEELKQVNVSMGLMLE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
QITPKLLKIVHKNSPSKIPHLRLQQLEWAGELRIPFTTGLLLGIGETVTDWKDTLEAISN
HHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHH
IHQKWGHIQEVIIQPYSPGSENKWVSDGFNVNLLPEVIAIANEVLPSNITLQIPPNLVKK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHCC
PEILLACLENGARDLGGIGPFDEINPDYPHPHYQALIKVLESRGWQLTKRLPVYSKYDDW
HHHHHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
LPINLKNIVSEWRIKLSIY
CCCCHHHHHHHHEEEEEEC
>Mature Secondary Structure 
SRIVTYSPAYTIVPTYECFNNCSYCNFRSDPGKSSWLSLSEAEKQLLSLKNKGTIEILT
CCEEEECCCEEEEECHHHHCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHCCCCCEEEEE
LSGEVHPNSKYRKAWFQLIYKLCQLALSLGFLPHTNVGILTRSEMEELKQVNVSMGLMLE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
QITPKLLKIVHKNSPSKIPHLRLQQLEWAGELRIPFTTGLLLGIGETVTDWKDTLEAISN
HHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHH
IHQKWGHIQEVIIQPYSPGSENKWVSDGFNVNLLPEVIAIANEVLPSNITLQIPPNLVKK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHCC
PEILLACLENGARDLGGIGPFDEINPDYPHPHYQALIKVLESRGWQLTKRLPVYSKYDDW
HHHHHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
LPINLKNIVSEWRIKLSIY
CCCCHHHHHHHHEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA