Click here to switch to the map view.

The map label for this gene is aroF [H]

Identifier: 113474075

GI number: 113474075

Start: 254069

End: 255130

Strand: Direct

Name: aroF [H]

Synonym: Tery_0171

Alternate gene names: 113474075

Gene position: 254069-255130 (Clockwise)

Preceding gene: 113474074

Following gene: 113474077

Centisome position: 3.28

GC content: 41.71

Gene sequence:

>1062_bases
ATGATAATAGTAACAAAAATCGGTTCTCCAGAAGTAGAGATAGATCGTCTTTGTCAGGAACTCAAAACTAATTGGGGTCT
AACTCCAGAAAAAATTGTTGGGCGCTATAAAGTTGTTATTGGTTTAGTAGGAGATACTGCAGACCTGGATCCATTACAAT
TACAGGAAATGAGTCCTTGGATCGAACAGGTAATGCGGGTTGAACGTCCTTACAAACGAGCAAGTCTAGAGTTTCATAAC
GGAGAAGCTAGTACAGTAGTAGTATCTACTCCAGATGGACCTATACCTTTTGGCCTTCATCAAGATCTAGTTGTAGTTGC
TGGACCCTGTTCGGTAGAAAATGAGCAAATGATTATAGAAACAGCTCAACGGGTGAAAGCTGCTGGTGCTAAGTTTTTGC
GTGGAGGTGCTTATAAACCTCGTACTTCTCCTTATTCTTTTCAGGGACATGGTGAGAGTGCTTTAAATTTGTTGGCTGCG
GCTAAAGAAAAAACTGGTCTGGGAATTATTACAGAAGTAATGGATGCTGCTGACTTACCAAGGTTGACTGAAGTTGCGGA
TGTGGTGCAAGTAGGTGCCCGTAATATGCAAAACTTTTCTCTATTAAAAAAGGTCGGTGCTCAAGATAAACCAGTGCTTT
TGAAGCGGGGAATGTCAGCTACTATTGAAGAGTGGCTAATGGCTGCAGAATATATTTTAGCAGCCGGAAATTCAAATGTA
ATTCTTTGTGAGCGCGGTGTTAGGACTTTTGATCGTCAGTATGCTCGTAATACTTTGGACTTGTCTGCAATACCAGTTTT
GCGATCGCTGACTCATTTACCAATTATGATTGACCCTAGTCATGGTACTGGTCGAGCTGAATATGTACCTGCAATGGCAA
TGGGAGCTATTGCTGCAGGAACAGATTCTCTAATGATTGAAGTCCATCCAAATCCAGCAAAAGCTCTGTCAGATGGCCCA
CAATCTCTAACACCAGATAAGTTTGATACCTTAATGGAGGAAATGGCAGTTATTGGTAAAAGTGTTAAACGTTGGCCACA
ACCGGAACCAGCCATTGTATAG

Upstream 100 bases:

>100_bases
AAGAAAATTTTAATAAGAAATTACTAGGACTTTACTATTTCAACTGATAGTTAAGGTAACCTTATATTGAACTTATACCT
ATTTGAGTGCAAAAGTATAA

Downstream 100 bases:

>100_bases
CTTTGATTAAAAATTGATTGATTTTATCTGCAATACAGCCAAAAAATTAAATCTTGATTGACAATTATTAGTCAGTTAAT
AACCGAGGCGATATCAGAGT

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIIVTKIGSPEVEIDRLCQELKTNWGLTPEKIVGRYKVVIGLVGDTADLDPLQLQEMSPWIEQVMRVERPYKRASLEFHN
GEASTVVVSTPDGPIPFGLHQDLVVVAGPCSVENEQMIIETAQRVKAAGAKFLRGGAYKPRTSPYSFQGHGESALNLLAA
AKEKTGLGIITEVMDAADLPRLTEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGMSATIEEWLMAAEYILAAGNSNV
ILCERGVRTFDRQYARNTLDLSAIPVLRSLTHLPIMIDPSHGTGRAEYVPAMAMGAIAAGTDSLMIEVHPNPAKALSDGP
QSLTPDKFDTLMEEMAVIGKSVKRWPQPEPAIV

Sequences:

>Translated_353_residues
MIIVTKIGSPEVEIDRLCQELKTNWGLTPEKIVGRYKVVIGLVGDTADLDPLQLQEMSPWIEQVMRVERPYKRASLEFHN
GEASTVVVSTPDGPIPFGLHQDLVVVAGPCSVENEQMIIETAQRVKAAGAKFLRGGAYKPRTSPYSFQGHGESALNLLAA
AKEKTGLGIITEVMDAADLPRLTEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGMSATIEEWLMAAEYILAAGNSNV
ILCERGVRTFDRQYARNTLDLSAIPVLRSLTHLPIMIDPSHGTGRAEYVPAMAMGAIAAGTDSLMIEVHPNPAKALSDGP
QSLTPDKFDTLMEEMAVIGKSVKRWPQPEPAIV
>Mature_353_residues
MIIVTKIGSPEVEIDRLCQELKTNWGLTPEKIVGRYKVVIGLVGDTADLDPLQLQEMSPWIEQVMRVERPYKRASLEFHN
GEASTVVVSTPDGPIPFGLHQDLVVVAGPCSVENEQMIIETAQRVKAAGAKFLRGGAYKPRTSPYSFQGHGESALNLLAA
AKEKTGLGIITEVMDAADLPRLTEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGMSATIEEWLMAAEYILAAGNSNV
ILCERGVRTFDRQYARNTLDLSAIPVLRSLTHLPIMIDPSHGTGRAEYVPAMAMGAIAAGTDSLMIEVHPNPAKALSDGP
QSLTPDKFDTLMEEMAVIGKSVKRWPQPEPAIV

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=226, Percent_Identity=26.5486725663717, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38374; Mature: 38374

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVTKIGSPEVEIDRLCQELKTNWGLTPEKIVGRYKVVIGLVGDTADLDPLQLQEMSPW
CEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCEEEEEEEEECCCCCCCCHHHHHCCHH
IEQVMRVERPYKRASLEFHNGEASTVVVSTPDGPIPFGLHQDLVVVAGPCSVENEQMIIE
HHHHHHHHCCHHHCCEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHH
TAQRVKAAGAKFLRGGAYKPRTSPYSFQGHGESALNLLAAAKEKTGLGIITEVMDAADLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
RLTEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGMSATIEEWLMAAEYILAAGNSNV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
ILCERGVRTFDRQYARNTLDLSAIPVLRSLTHLPIMIDPSHGTGRAEYVPAMAMGAIAAG
EEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCC
TDSLMIEVHPNPAKALSDGPQSLTPDKFDTLMEEMAVIGKSVKRWPQPEPAIV
CCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIIVTKIGSPEVEIDRLCQELKTNWGLTPEKIVGRYKVVIGLVGDTADLDPLQLQEMSPW
CEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCEEEEEEEEECCCCCCCCHHHHHCCHH
IEQVMRVERPYKRASLEFHNGEASTVVVSTPDGPIPFGLHQDLVVVAGPCSVENEQMIIE
HHHHHHHHCCHHHCCEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHH
TAQRVKAAGAKFLRGGAYKPRTSPYSFQGHGESALNLLAAAKEKTGLGIITEVMDAADLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
RLTEVADVVQVGARNMQNFSLLKKVGAQDKPVLLKRGMSATIEEWLMAAEYILAAGNSNV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
ILCERGVRTFDRQYARNTLDLSAIPVLRSLTHLPIMIDPSHGTGRAEYVPAMAMGAIAAG
EEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCC
TDSLMIEVHPNPAKALSDGPQSLTPDKFDTLMEEMAVIGKSVKRWPQPEPAIV
CCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]