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The map label for this gene is ligA [H]

Identifier: 110835563

GI number: 110835563

Start: 3055822

End: 3056673

Strand: Reverse

Name: ligA [H]

Synonym: ABO_2702

Alternate gene names: 110835563

Gene position: 3056673-3055822 (Counterclockwise)

Preceding gene: 110835565

Following gene: 110835560

Centisome position: 97.97

GC content: 58.22

Gene sequence:

>852_bases
GTGAAGAGCAGGCAAGGGCTGGCGATTATTGGTCTGTGGATAATGGCTGGCTGGTGTTTGGCGCAGGGCCCGGCACTTCA
GCTAGCGCAGACATATCAGCAGGGAATGGCCCTGGAGGGGTACTGGGTCAGCGAAAAGCTGGATGGGGTGAGAGCTTACT
GGAATGGGGAGCACTTGATCAGTAAAGGGGGGTATGTGATCAATGCCCCGGCTTGGTTTGTGCGCGGTTACCCGAGTACG
CCTATGGACGGGGAGCTGTGGATGGGGCGCGGGCGTTTTTCGGCTGTTTCTGCAGCGGTGCGGCGGGTGCAGCCCAACGC
TGAGGAGTGGCGGCACATTCGATATAAGGTGTTTGATTTGCCGGCCAGTGGTGCGCCATTCTCACAGCGTATTCAACAAA
TGAAGGCGCTGGCGTCAGCCAGCAATGGCTATACCTTTTCCGTCATAGAACAGCAGCCGGCCTCAAGTCACGCGGCATTA
TTACAGCGGTTAGACAAGGTGATGGCGGCAGGGGGGGAAGGGCTGATGCTGCATCACGGCGATAGCCTGTACCAGGCGGG
CCGCAGTGATGCGGTGTTGAAAGTGAAGACCTATCAAGATGCGGAAGCGGTGGTGATTGGCTACACAGCAGGCAAGGGGA
AATACCGTGGCATGATGGGGGCGCTGGTGGTTGAAAGGGCGGATGGTCGGCAATTCAAGCTGGGGACCGGCTTTACTGAT
AAACAGCGCAAGGCACCGCCGCCCTTGGGGGCCACGGTGACTTACAAGTATTTCGGAAAAACGGCTACGGGGCTGCCCCG
CTTTGCCCGTTTTCTGCGTATTCGACGCGATGAACCTTTGGCCGAGCCGTAA

Upstream 100 bases:

>100_bases
GCAAACCGTTATGGCTTACATCACCGGTATGTGTAAACGGACAGGGAGCGGAGCCCGAATCTGTCATGGTACCAGCCTGA
CATAAACCGGGGGCAATGCC

Downstream 100 bases:

>100_bases
GGGGGCTGGTGTTATTTCGGGTACAGCGATATTACCCGGCCCACCGTGCGGGGCAGGCCGGGATGCCTCAGGGTTGCAGG
TTCAGTTCGTAGATGGCTTC

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKSRQGLAIIGLWIMAGWCLAQGPALQLAQTYQQGMALEGYWVSEKLDGVRAYWNGEHLISKGGYVINAPAWFVRGYPST
PMDGELWMGRGRFSAVSAAVRRVQPNAEEWRHIRYKVFDLPASGAPFSQRIQQMKALASASNGYTFSVIEQQPASSHAAL
LQRLDKVMAAGGEGLMLHHGDSLYQAGRSDAVLKVKTYQDAEAVVIGYTAGKGKYRGMMGALVVERADGRQFKLGTGFTD
KQRKAPPPLGATVTYKYFGKTATGLPRFARFLRIRRDEPLAEP

Sequences:

>Translated_283_residues
MKSRQGLAIIGLWIMAGWCLAQGPALQLAQTYQQGMALEGYWVSEKLDGVRAYWNGEHLISKGGYVINAPAWFVRGYPST
PMDGELWMGRGRFSAVSAAVRRVQPNAEEWRHIRYKVFDLPASGAPFSQRIQQMKALASASNGYTFSVIEQQPASSHAAL
LQRLDKVMAAGGEGLMLHHGDSLYQAGRSDAVLKVKTYQDAEAVVIGYTAGKGKYRGMMGALVVERADGRQFKLGTGFTD
KQRKAPPPLGATVTYKYFGKTATGLPRFARFLRIRRDEPLAEP
>Mature_283_residues
MKSRQGLAIIGLWIMAGWCLAQGPALQLAQTYQQGMALEGYWVSEKLDGVRAYWNGEHLISKGGYVINAPAWFVRGYPST
PMDGELWMGRGRFSAVSAAVRRVQPNAEEWRHIRYKVFDLPASGAPFSQRIQQMKALASASNGYTFSVIEQQPASSHAAL
LQRLDKVMAAGGEGLMLHHGDSLYQAGRSDAVLKVKTYQDAEAVVIGYTAGKGKYRGMMGALVVERADGRQFKLGTGFTD
KQRKAPPPLGATVTYKYFGKTATGLPRFARFLRIRRDEPLAEP

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 31177; Mature: 31177

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRQGLAIIGLWIMAGWCLAQGPALQLAQTYQQGMALEGYWVSEKLDGVRAYWNGEHLI
CCCCCCHHHEEHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEHHHHCCCEEEEECCCEEE
SKGGYVINAPAWFVRGYPSTPMDGELWMGRGRFSAVSAAVRRVQPNAEEWRHIRYKVFDL
ECCCEEEECCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHEEEEEEEEC
PASGAPFSQRIQQMKALASASNGYTFSVIEQQPASSHAALLQRLDKVMAAGGEGLMLHHG
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECC
DSLYQAGRSDAVLKVKTYQDAEAVVIGYTAGKGKYRGMMGALVVERADGRQFKLGTGFTD
CHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHEEEEEECCCCCEEEECCCCCC
KQRKAPPPLGATVTYKYFGKTATGLPRFARFLRIRRDEPLAEP
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKSRQGLAIIGLWIMAGWCLAQGPALQLAQTYQQGMALEGYWVSEKLDGVRAYWNGEHLI
CCCCCCHHHEEHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEHHHHCCCEEEEECCCEEE
SKGGYVINAPAWFVRGYPSTPMDGELWMGRGRFSAVSAAVRRVQPNAEEWRHIRYKVFDL
ECCCEEEECCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHEEEEEEEEC
PASGAPFSQRIQQMKALASASNGYTFSVIEQQPASSHAALLQRLDKVMAAGGEGLMLHHG
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECC
DSLYQAGRSDAVLKVKTYQDAEAVVIGYTAGKGKYRGMMGALVVERADGRQFKLGTGFTD
CHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHEEEEEECCCCCEEEECCCCCC
KQRKAPPPLGATVTYKYFGKTATGLPRFARFLRIRRDEPLAEP
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]