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The map label for this gene is hupR1 [H]

Identifier: 110835380

GI number: 110835380

Start: 2857114

End: 2857581

Strand: Direct

Name: hupR1 [H]

Synonym: ABO_2519

Alternate gene names: 110835380

Gene position: 2857114-2857581 (Clockwise)

Preceding gene: 110835378

Following gene: 110835381

Centisome position: 91.57

GC content: 51.5

Gene sequence:

>468_bases
GTGAATGAGAGATTCATCATGTATCAGGTCATGATCGTGGATGATGAGGAGTACATCCTCAAAGCCTTGAAACGCACCAT
CAATACCTACACCGACTGGGATGTCGAGACCTATCAGAGCCCCCACGAAGCCCTGCGCCGGGCACGCACCACGGTTTTCG
ATGCGGTCATCACCGACTATATGATGCCGGAAATGAACGGTTTGGAGCTGCTTCAGGAACTGCGCGAGCTGCAGCCGGAT
ACTATTCGCATTGTGCTGACCGGGGTGATCGACATCGAAACGGTCATGTCGGCCATTAACAAGGCCGGTGCATTTCGCTT
TATCCCCAAACCTTGGGATGACGAGCAACTCCTCGACAACATTCGTGAAGGCTTAAAATTCCGTGACATTCTTTTGGAAA
ATCGAATGCTCGCAGAAACGGTTCGGGAGCAACAAGAAGCCTTGCGTAGTATGGGTTATGAGGGCTAG

Upstream 100 bases:

>100_bases
AACCTAATACTCCCGTCCCTGTCCTGTCGACACATAGGGCAGGACGCAATGTTGCTGAGCGCACGCAGTCGCCGACAGGA
CGCCAGCGTAATATCACGCT

Downstream 100 bases:

>100_bases
GCCCTTAACTTTTCGCCCTTCAAACAACTAATAACGGCTCGGCGCATGAACAGCTTGCTGGACAAAACGAGTATTGGCTT
TGGCATGGAAGCTCAAGGGC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MNERFIMYQVMIVDDEEYILKALKRTINTYTDWDVETYQSPHEALRRARTTVFDAVITDYMMPEMNGLELLQELRELQPD
TIRIVLTGVIDIETVMSAINKAGAFRFIPKPWDDEQLLDNIREGLKFRDILLENRMLAETVREQQEALRSMGYEG

Sequences:

>Translated_155_residues
MNERFIMYQVMIVDDEEYILKALKRTINTYTDWDVETYQSPHEALRRARTTVFDAVITDYMMPEMNGLELLQELRELQPD
TIRIVLTGVIDIETVMSAINKAGAFRFIPKPWDDEQLLDNIREGLKFRDILLENRMLAETVREQQEALRSMGYEG
>Mature_155_residues
MNERFIMYQVMIVDDEEYILKALKRTINTYTDWDVETYQSPHEALRRARTTVFDAVITDYMMPEMNGLELLQELRELQPD
TIRIVLTGVIDIETVMSAINKAGAFRFIPKPWDDEQLLDNIREGLKFRDILLENRMLAETVREQQEALRSMGYEG

Specific function: Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 18267; Mature: 18267

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERFIMYQVMIVDDEEYILKALKRTINTYTDWDVETYQSPHEALRRARTTVFDAVITDY
CCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
MMPEMNGLELLQELRELQPDTIRIVLTGVIDIETVMSAINKAGAFRFIPKPWDDEQLLDN
HCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
IREGLKFRDILLENRMLAETVREQQEALRSMGYEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNERFIMYQVMIVDDEEYILKALKRTINTYTDWDVETYQSPHEALRRARTTVFDAVITDY
CCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
MMPEMNGLELLQELRELQPDTIRIVLTGVIDIETVMSAINKAGAFRFIPKPWDDEQLLDN
HCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
IREGLKFRDILLENRMLAETVREQQEALRSMGYEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1885559; 8497190; 2007559 [H]