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The map label for this gene is luxQ [H]

Identifier: 110835378

GI number: 110835378

Start: 2854348

End: 2856168

Strand: Direct

Name: luxQ [H]

Synonym: ABO_2517

Alternate gene names: 110835378

Gene position: 2854348-2856168 (Clockwise)

Preceding gene: 110835376

Following gene: 110835380

Centisome position: 91.48

GC content: 54.37

Gene sequence:

>1821_bases
ATGGGTGAATTTCACCCGAGGGCGCTTACATGCCGTAATAATCGGGCTAGACTGGGTGCCAGTCATTTTACAAACCCGCC
AGCCATGCCAGAAACCCTTCGTCGTGCGGTGACGGAAAACCGCGAACGCATCCTTCAGGAGCGCCACAACCTGTTCATGG
AAGAGGTGGGGTCACGCATGGTGCTGTCGTTTTTTATTGCAGCGGCACTGCCATTATTTTTTCTGAAGCTGCGTACAGAG
CCGCCCTTTATCGGCTGGTATACCGTGCTGCTTTGTGTCGCAGCACAATCTTTTTTCCTCATCCGGTTTTACAACGCCCA
TCGGGAACACGAAGCGCCTAAAACCCGGAAATGGCATCGGCTAAACCTCTACCTTGCCGTGATCTGGGCGATACTGTGGT
CAAGTTTCCCTTATCTCTTCCTGCAAGGGGCCACGCCGGTAACCCTGCTGACCTGTCTGGTTATCCTCTCGGTGGCCACC
TCGATCCCGTCTGTATCCATGGGTGTGTATCCGGATATTTTTATCAGTTTCATAACACCGGTTTATCTCGCCTGGCTGGC
CTTTATTCTGATTTACGTACCGCAAGCGCCAGGGATCATCAAAATCATTCCGTTGGCCAACCTGATTTCCATGATCGTGT
TTAGTCTTTATGTTCACCGCACACAGATCAGCACTATCGCCCTGCGAATTGAAGCAGAACAGGCCAAAGAACGTGCCCGC
AAGGCCAGTGAAAGCAAAACCCGGTTTCTGGCCGCCGCTAGCCACGACCTGAGGCAACCGCTGCAGGCGGCCACCCTGTA
TGCCGCCATGCTGAAAAACAATGCCGACCCACAACCCGATATCGTCGACAAGCTGGATACCGCCATTGGCTCCTGCAATG
AACTGCTGGGGCACTTGCTCATGCTGTCGCGCTTGCAGTCCAGGCGACTAAAACCCCGCAAACGCATTATCAGCCTACTG
GACACCTTGCAGCCCATCCTTGATGAAATTCGACCACAGGCAAACGCAAAGCAACTGGCTGTGGTCACCAAAAATCTAGC
CGGCCAGCATGTGTTCGCCGATGGGGTCATGCTCGCTCGCATTGTCCGCAACCTGGTCAATAATGCCCTCAAATACACCG
AGCGCGGGCATATTCGTATTGCCGCCCGGCAGCAGGACAATCAATTGTTGCTGGACATCGCAGACACCGGCATCGGGATT
GACGAAATCTATCAGTTCGAGGTGTTCGACGAATTCATGCAGATAGACAACGACCAACGTTCGATCCAGAACGGACTAGG
GCTGGGCCTCGCCATCGTCAGCCGACTGGCTGCACTGTGCGACATTCCGTTCAATATGCAGTCACGCAAGGGCGAAGGCA
CCACCTTCACGTTGACGTTACCGGCGGCGGCCTCCAGCCAGACACAGCCCGCTCACAACGTGGTCAATGCGCTGCCACTG
TTTGAAACACTGACCGTGCTATTGATAGATGATGACAAAAGGGTTACAGAAGCCCTGAGCAGCCTGCTGGGCAACCTGGG
CGCAACAGTAACTGCCCACCACTCGCTGGAGCCAGCCATGCAGGCATTGAAAAAGCGAGGCGCGCCACCTTCAGTGGTCA
TTACCGATGATCAGATAGGACCGCATACTAATGCGGGCTCGGTCATCGCCGCGGTAACCGCATTGTTCCGCCAGCCAATT
CCCGCCCTGATCATCACCGGCAATACCGATCCGCAATTCATTCAGTCCTTGCCGGAGGACATTGATGTGCTGTTCAAACC
GGTAGCAGCGGATACGCTAACCGCAAAACTGGAGGAAATGATGTCCTCCAAGAAAAGCTAA

Upstream 100 bases:

>100_bases
GAGTGAGTTGCTTGTTGATCATTGCGCTTACCCCGATTGGTTACTCATCCCAGAGAGGCGTTTATTAGAGCACCGGGAGG
AATTTGGCTTCTTCACCCTG

Downstream 100 bases:

>100_bases
AGCAGGCCTATCTGGCGGGCTTTTTCGATACAGGCGGTGCGGTTAGGCACGTCCAGTTTTTCGTAGAGTAGTCGCAAGTG
GGTCTTGATGGTGTTCACGC

Product: two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MGEFHPRALTCRNNRARLGASHFTNPPAMPETLRRAVTENRERILQERHNLFMEEVGSRMVLSFFIAAALPLFFLKLRTE
PPFIGWYTVLLCVAAQSFFLIRFYNAHREHEAPKTRKWHRLNLYLAVIWAILWSSFPYLFLQGATPVTLLTCLVILSVAT
SIPSVSMGVYPDIFISFITPVYLAWLAFILIYVPQAPGIIKIIPLANLISMIVFSLYVHRTQISTIALRIEAEQAKERAR
KASESKTRFLAAASHDLRQPLQAATLYAAMLKNNADPQPDIVDKLDTAIGSCNELLGHLLMLSRLQSRRLKPRKRIISLL
DTLQPILDEIRPQANAKQLAVVTKNLAGQHVFADGVMLARIVRNLVNNALKYTERGHIRIAARQQDNQLLLDIADTGIGI
DEIYQFEVFDEFMQIDNDQRSIQNGLGLGLAIVSRLAALCDIPFNMQSRKGEGTTFTLTLPAAASSQTQPAHNVVNALPL
FETLTVLLIDDDKRVTEALSSLLGNLGATVTAHHSLEPAMQALKKRGAPPSVVITDDQIGPHTNAGSVIAAVTALFRQPI
PALIITGNTDPQFIQSLPEDIDVLFKPVAADTLTAKLEEMMSSKKS

Sequences:

>Translated_606_residues
MGEFHPRALTCRNNRARLGASHFTNPPAMPETLRRAVTENRERILQERHNLFMEEVGSRMVLSFFIAAALPLFFLKLRTE
PPFIGWYTVLLCVAAQSFFLIRFYNAHREHEAPKTRKWHRLNLYLAVIWAILWSSFPYLFLQGATPVTLLTCLVILSVAT
SIPSVSMGVYPDIFISFITPVYLAWLAFILIYVPQAPGIIKIIPLANLISMIVFSLYVHRTQISTIALRIEAEQAKERAR
KASESKTRFLAAASHDLRQPLQAATLYAAMLKNNADPQPDIVDKLDTAIGSCNELLGHLLMLSRLQSRRLKPRKRIISLL
DTLQPILDEIRPQANAKQLAVVTKNLAGQHVFADGVMLARIVRNLVNNALKYTERGHIRIAARQQDNQLLLDIADTGIGI
DEIYQFEVFDEFMQIDNDQRSIQNGLGLGLAIVSRLAALCDIPFNMQSRKGEGTTFTLTLPAAASSQTQPAHNVVNALPL
FETLTVLLIDDDKRVTEALSSLLGNLGATVTAHHSLEPAMQALKKRGAPPSVVITDDQIGPHTNAGSVIAAVTALFRQPI
PALIITGNTDPQFIQSLPEDIDVLFKPVAADTLTAKLEEMMSSKKS
>Mature_605_residues
GEFHPRALTCRNNRARLGASHFTNPPAMPETLRRAVTENRERILQERHNLFMEEVGSRMVLSFFIAAALPLFFLKLRTEP
PFIGWYTVLLCVAAQSFFLIRFYNAHREHEAPKTRKWHRLNLYLAVIWAILWSSFPYLFLQGATPVTLLTCLVILSVATS
IPSVSMGVYPDIFISFITPVYLAWLAFILIYVPQAPGIIKIIPLANLISMIVFSLYVHRTQISTIALRIEAEQAKERARK
ASESKTRFLAAASHDLRQPLQAATLYAAMLKNNADPQPDIVDKLDTAIGSCNELLGHLLMLSRLQSRRLKPRKRIISLLD
TLQPILDEIRPQANAKQLAVVTKNLAGQHVFADGVMLARIVRNLVNNALKYTERGHIRIAARQQDNQLLLDIADTGIGID
EIYQFEVFDEFMQIDNDQRSIQNGLGLGLAIVSRLAALCDIPFNMQSRKGEGTTFTLTLPAAASSQTQPAHNVVNALPLF
ETLTVLLIDDDKRVTEALSSLLGNLGATVTAHHSLEPAMQALKKRGAPPSVVITDDQIGPHTNAGSVIAAVTALFRQPIP
ALIITGNTDPQFIQSLPEDIDVLFKPVAADTLTAKLEEMMSSKKS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=341, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081816, Length=418, Percent_Identity=25.8373205741627, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=387, Percent_Identity=24.8062015503876, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=32.7868852459016, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=26.2962962962963, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790551, Length=211, Percent_Identity=30.8056872037915, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=24.6753246753247, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=27.2340425531915, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788393, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=26.8292682926829, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67324; Mature: 67193

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFHPRALTCRNNRARLGASHFTNPPAMPETLRRAVTENRERILQERHNLFMEEVGSRM
CCCCCCCEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSFFIAAALPLFFLKLRTEPPFIGWYTVLLCVAAQSFFLIRFYNAHREHEAPKTRKWHR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LNLYLAVIWAILWSSFPYLFLQGATPVTLLTCLVILSVATSIPSVSMGVYPDIFISFITP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VYLAWLAFILIYVPQAPGIIKIIPLANLISMIVFSLYVHRTQISTIALRIEAEQAKERAR
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHH
KASESKTRFLAAASHDLRQPLQAATLYAAMLKNNADPQPDIVDKLDTAIGSCNELLGHLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MLSRLQSRRLKPRKRIISLLDTLQPILDEIRPQANAKQLAVVTKNLAGQHVFADGVMLAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
IVRNLVNNALKYTERGHIRIAARQQDNQLLLDIADTGIGIDEIYQFEVFDEFMQIDNDQR
HHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHH
SIQNGLGLGLAIVSRLAALCDIPFNMQSRKGEGTTFTLTLPAAASSQTQPAHNVVNALPL
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
FETLTVLLIDDDKRVTEALSSLLGNLGATVTAHHSLEPAMQALKKRGAPPSVVITDDQIG
HHHHEEEEECCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCC
PHTNAGSVIAAVTALFRQPIPALIITGNTDPQFIQSLPEDIDVLFKPVAADTLTAKLEEM
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
MSSKKS
HHCCCC
>Mature Secondary Structure 
GEFHPRALTCRNNRARLGASHFTNPPAMPETLRRAVTENRERILQERHNLFMEEVGSRM
CCCCCCEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSFFIAAALPLFFLKLRTEPPFIGWYTVLLCVAAQSFFLIRFYNAHREHEAPKTRKWHR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LNLYLAVIWAILWSSFPYLFLQGATPVTLLTCLVILSVATSIPSVSMGVYPDIFISFITP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VYLAWLAFILIYVPQAPGIIKIIPLANLISMIVFSLYVHRTQISTIALRIEAEQAKERAR
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHH
KASESKTRFLAAASHDLRQPLQAATLYAAMLKNNADPQPDIVDKLDTAIGSCNELLGHLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MLSRLQSRRLKPRKRIISLLDTLQPILDEIRPQANAKQLAVVTKNLAGQHVFADGVMLAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
IVRNLVNNALKYTERGHIRIAARQQDNQLLLDIADTGIGIDEIYQFEVFDEFMQIDNDQR
HHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHH
SIQNGLGLGLAIVSRLAALCDIPFNMQSRKGEGTTFTLTLPAAASSQTQPAHNVVNALPL
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
FETLTVLLIDDDKRVTEALSSLLGNLGATVTAHHSLEPAMQALKKRGAPPSVVITDDQIG
HHHHEEEEECCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCCCC
PHTNAGSVIAAVTALFRQPIPALIITGNTDPQFIQSLPEDIDVLFKPVAADTLTAKLEEM
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
MSSKKS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]