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The map label for this gene is efp

Identifier: 110835307

GI number: 110835307

Start: 2771299

End: 2771868

Strand: Direct

Name: efp

Synonym: ABO_2446

Alternate gene names: 110835307

Gene position: 2771299-2771868 (Clockwise)

Preceding gene: 110835303

Following gene: 110835308

Centisome position: 88.82

GC content: 54.91

Gene sequence:

>570_bases
ATGGCCAACTATTCTACCAGCGAATTCAAGTCTGGCTTGAAAGTGATGCTCGATGGCGATCCCTGTTCCATCATCGAAAA
CGAATTCGTCAAGCCGGGCAAGGGTCAGGCGTTCAGCCGCGTAAAGCTACGCAACCTGCGTAACGGTAAGGTTTGGGAAC
GTACCTTCAAGTCTGGTGACTCCTTGGAGGGTGCTGACGTAATGGACGTTTCCATGCAGTACATCTACAGCGACGGCGAA
TTTTGGCACTTCATGGACCAAACCTCCTTCGAACAGAAGCAAGCCGACGAAACCGCGGTTCGCGACGCCAAGCAGTGGCT
CAAGGAAGAAGACATCTGCGAGGTTACTCTTTACAACGGTGAGCCCTTGTCCGTTAGCCCCCCCAATTTTGTTGAGTTGG
AAATCATCGAAACCGACCCAGGCCTCAAAGGCGACACCGCCGGCACCGGTGGAAAGCCCGCCACACTGAGCACCGGCGCA
GTGGTACGTGTCCCGCTGTTCGTACAGACCGGTGAAATCGTCAAAGTCGACACCCGTACCGGCGATTACGTGGGCCGCAT
CAAACAGTAG

Upstream 100 bases:

>100_bases
TAGATTGGCGAGCGTGCAGGCGCAACAGAGATGCAGATGAAACATCAACAGACCCTATCAACCGCTCAAGTTGCATACAT
CAACTCTTTGGAAAAGTTTT

Downstream 100 bases:

>100_bases
CCATGAGCAACTGGCAGCCCACCGCCTCTTTGCAGGCCATCAAGGCGCGCGCTGAACTACTAAGCACAGTGCGCGCCTTT
TTTGATGCCCGCCAAGTACT

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MANYSTSEFKSGLKVMLDGDPCSIIENEFVKPGKGQAFSRVKLRNLRNGKVWERTFKSGDSLEGADVMDVSMQYIYSDGE
FWHFMDQTSFEQKQADETAVRDAKQWLKEEDICEVTLYNGEPLSVSPPNFVELEIIETDPGLKGDTAGTGGKPATLSTGA
VVRVPLFVQTGEIVKVDTRTGDYVGRIKQ

Sequences:

>Translated_189_residues
MANYSTSEFKSGLKVMLDGDPCSIIENEFVKPGKGQAFSRVKLRNLRNGKVWERTFKSGDSLEGADVMDVSMQYIYSDGE
FWHFMDQTSFEQKQADETAVRDAKQWLKEEDICEVTLYNGEPLSVSPPNFVELEIIETDPGLKGDTAGTGGKPATLSTGA
VVRVPLFVQTGEIVKVDTRTGDYVGRIKQ
>Mature_188_residues
ANYSTSEFKSGLKVMLDGDPCSIIENEFVKPGKGQAFSRVKLRNLRNGKVWERTFKSGDSLEGADVMDVSMQYIYSDGEF
WHFMDQTSFEQKQADETAVRDAKQWLKEEDICEVTLYNGEPLSVSPPNFVELEIIETDPGLKGDTAGTGGKPATLSTGAV
VRVPLFVQTGEIVKVDTRTGDYVGRIKQ

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=65.4255319148936, Blast_Score=271, Evalue=2e-74,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=28.2608695652174, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ALCBS (Q0VLQ4)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694166.1
- STRING:   Q0VLQ4
- GeneID:   4213344
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2446
- NMPDR:   fig|393595.12.peg.2447
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q0VLQ4
- BioCyc:   ABOR393595:ABO_2446-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20986; Mature: 20855

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYSTSEFKSGLKVMLDGDPCSIIENEFVKPGKGQAFSRVKLRNLRNGKVWERTFKSGD
CCCCCCHHHCCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCC
SLEGADVMDVSMQYIYSDGEFWHFMDQTSFEQKQADETAVRDAKQWLKEEDICEVTLYNG
CCCCCCEEEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
EPLSVSPPNFVELEIIETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQTGEIVKVDTRT
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCEEEEECCC
GDYVGRIKQ
CCCHHCCCC
>Mature Secondary Structure 
ANYSTSEFKSGLKVMLDGDPCSIIENEFVKPGKGQAFSRVKLRNLRNGKVWERTFKSGD
CCCCCHHHCCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCC
SLEGADVMDVSMQYIYSDGEFWHFMDQTSFEQKQADETAVRDAKQWLKEEDICEVTLYNG
CCCCCCEEEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
EPLSVSPPNFVELEIIETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQTGEIVKVDTRT
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCEEEEECCC
GDYVGRIKQ
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA