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The map label for this gene is serB [H]

Identifier: 110835303

GI number: 110835303

Start: 2764335

End: 2765570

Strand: Direct

Name: serB [H]

Synonym: ABO_2442

Alternate gene names: 110835303

Gene position: 2764335-2765570 (Clockwise)

Preceding gene: 110835300

Following gene: 110835307

Centisome position: 88.6

GC content: 55.74

Gene sequence:

>1236_bases
GTGCGCGAGATCATTCTGATCCAGGTATCTGGTAATGACCGGCCGGGTTTGACCGCCGCCTTCACCGGCATTCTTGCCCG
TTATCGGCTCAACATTCTGGATATCGGCCAGGCCGTCATCCACGACACCTTGTCGCTGGGGATTTTGGTGGAAACGCCTC
AGGATGCTGACTCTTCATCAGTCCTCAAGGATCTGCTTTTCGAGGCGCACAAGCTGAATATCAATGTGCGCTTCCGGCCC
ATCGACGAGGACCGCTACGAAGAGTGGGTCGCAGGCCAAGGCAAGGACCGCCATATCATCACCCTGCTAGCGCGCAAGAT
CACCGCCGAGCAACTAGCCGATGTCACCACTACCGTGGCCGACAATGGACTCAACATTGATAGTATAGCTAGGCTATCTG
GACGTGTTCACCTAGAAGGGGAAGCCCTTAACGAGGACAACCGCGCCTGCATTGAAATTTCCGTGCGCGGCGAACCCCAG
AACGGTGAGGCTATGCGTGCAGCCTTCCTGAGCATTGCCAACGAACGCAACTTGGATATCGCTTTCCAGCGCGACAGTGC
CTACCGGCGCAACCGGCGCTTGGTGGTATTCGATATGGATTCCACCCTGATTCGCTCCGAAGTGATCGACGAACTGGCGA
CAGAAGCCGGCGTCGGCAAACAAGTGGCCGAGATTACCGAGCAGGCCATGCGCGGCGAGCTAGACTTTAATGAGAGCTTT
AAAGCTCGCGTCGCCCTGCTTAAAGGCTTGGACGAAGGCGCCTTGGAACGAGTGCGTGAACGCATCCAGCTCACCGAAGG
TGCTGAACGGTTAATCTCTACACTACGCGCCCTAGGCTACCGAACCGCCATCCTTTCCGGCGGTTTCACTTGGTTTGGGC
AATGGCTACAAGAACTATTGGGGATTGATTATATCCACGCCAACGAGCTGGAAATCGAAAACGGCCAGGTCACGGGTCGG
GTGGTAGGGCAGATCGTCAACGGCCAGCGCAAGGCGGAACTGTTAAGAGGTATCGCGGCTCAAGAAGGTATTAGCCTGGA
ACAGGTTATCGCCGTAGGTGATGGTGCCAACGACCTACCCATGCTTGGTGAAGCAGGCCTGGGTATTGCTTTTCGCGCCA
AGCCCTTGGTCAAACAGAATGCGGAACAGGCCATTTCCACCCTAGGTCTGGACGGCATTCTTTATTTAATCGGGGTACGC
GACAAGGACCAAGCGGAACTATTGAAGGGTAACTGA

Upstream 100 bases:

>100_bases
ACTCTTACATCGCCGTTTCGGCTCGAATACGACGCCGACTATCTAGCTAACATTTTTCACCTTCTGGCACTTTTTATTTT
CTGGCACTGGGAGCCCACGC

Downstream 100 bases:

>100_bases
GAATAGCTGAAACTCGATCGCGCTCGCCAGCTTAGGCCTGTGACTATAAGTGTAAGAGGCCGCGCCCATGTTTTGGGCGC
GGCCTCTTACGTTGCACAAT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MREIILIQVSGNDRPGLTAAFTGILARYRLNILDIGQAVIHDTLSLGILVETPQDADSSSVLKDLLFEAHKLNINVRFRP
IDEDRYEEWVAGQGKDRHIITLLARKITAEQLADVTTTVADNGLNIDSIARLSGRVHLEGEALNEDNRACIEISVRGEPQ
NGEAMRAAFLSIANERNLDIAFQRDSAYRRNRRLVVFDMDSTLIRSEVIDELATEAGVGKQVAEITEQAMRGELDFNESF
KARVALLKGLDEGALERVRERIQLTEGAERLISTLRALGYRTAILSGGFTWFGQWLQELLGIDYIHANELEIENGQVTGR
VVGQIVNGQRKAELLRGIAAQEGISLEQVIAVGDGANDLPMLGEAGLGIAFRAKPLVKQNAEQAISTLGLDGILYLIGVR
DKDQAELLKGN

Sequences:

>Translated_411_residues
MREIILIQVSGNDRPGLTAAFTGILARYRLNILDIGQAVIHDTLSLGILVETPQDADSSSVLKDLLFEAHKLNINVRFRP
IDEDRYEEWVAGQGKDRHIITLLARKITAEQLADVTTTVADNGLNIDSIARLSGRVHLEGEALNEDNRACIEISVRGEPQ
NGEAMRAAFLSIANERNLDIAFQRDSAYRRNRRLVVFDMDSTLIRSEVIDELATEAGVGKQVAEITEQAMRGELDFNESF
KARVALLKGLDEGALERVRERIQLTEGAERLISTLRALGYRTAILSGGFTWFGQWLQELLGIDYIHANELEIENGQVTGR
VVGQIVNGQRKAELLRGIAAQEGISLEQVIAVGDGANDLPMLGEAGLGIAFRAKPLVKQNAEQAISTLGLDGILYLIGVR
DKDQAELLKGN
>Mature_411_residues
MREIILIQVSGNDRPGLTAAFTGILARYRLNILDIGQAVIHDTLSLGILVETPQDADSSSVLKDLLFEAHKLNINVRFRP
IDEDRYEEWVAGQGKDRHIITLLARKITAEQLADVTTTVADNGLNIDSIARLSGRVHLEGEALNEDNRACIEISVRGEPQ
NGEAMRAAFLSIANERNLDIAFQRDSAYRRNRRLVVFDMDSTLIRSEVIDELATEAGVGKQVAEITEQAMRGELDFNESF
KARVALLKGLDEGALERVRERIQLTEGAERLISTLRALGYRTAILSGGFTWFGQWLQELLGIDYIHANELEIENGQVTGR
VVGQIVNGQRKAELLRGIAAQEGISLEQVIAVGDGANDLPMLGEAGLGIAFRAKPLVKQNAEQAISTLGLDGILYLIGVR
DKDQAELLKGN

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790849, Length=226, Percent_Identity=48.2300884955752, Blast_Score=206, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI115534456, Length=189, Percent_Identity=32.8042328042328, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534454, Length=189, Percent_Identity=32.8042328042328, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534458, Length=191, Percent_Identity=32.4607329842932, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321647, Length=312, Percent_Identity=36.2179487179487, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24661601, Length=223, Percent_Identity=28.6995515695067, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 45199; Mature: 45199

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIILIQVSGNDRPGLTAAFTGILARYRLNILDIGQAVIHDTLSLGILVETPQDADSSS
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCHHH
VLKDLLFEAHKLNINVRFRPIDEDRYEEWVAGQGKDRHIITLLARKITAEQLADVTTTVA
HHHHHHHHHHEEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DNGLNIDSIARLSGRVHLEGEALNEDNRACIEISVRGEPQNGEAMRAAFLSIANERNLDI
CCCCCHHHHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEE
AFQRDSAYRRNRRLVVFDMDSTLIRSEVIDELATEAGVGKQVAEITEQAMRGELDFNESF
EEECCCHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHH
KARVALLKGLDEGALERVRERIQLTEGAERLISTLRALGYRTAILSGGFTWFGQWLQELL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GIDYIHANELEIENGQVTGRVVGQIVNGQRKAELLRGIAAQEGISLEQVIAVGDGANDLP
CCCEEECCCEEECCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCC
MLGEAGLGIAFRAKPLVKQNAEQAISTLGLDGILYLIGVRDKDQAELLKGN
CCCCCCCCEEEECCHHHHCCHHHHHHHHCCCCEEEEEECCCCCHHHHCCCC
>Mature Secondary Structure
MREIILIQVSGNDRPGLTAAFTGILARYRLNILDIGQAVIHDTLSLGILVETPQDADSSS
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCHHH
VLKDLLFEAHKLNINVRFRPIDEDRYEEWVAGQGKDRHIITLLARKITAEQLADVTTTVA
HHHHHHHHHHEEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DNGLNIDSIARLSGRVHLEGEALNEDNRACIEISVRGEPQNGEAMRAAFLSIANERNLDI
CCCCCHHHHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEE
AFQRDSAYRRNRRLVVFDMDSTLIRSEVIDELATEAGVGKQVAEITEQAMRGELDFNESF
EEECCCHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHH
KARVALLKGLDEGALERVRERIQLTEGAERLISTLRALGYRTAILSGGFTWFGQWLQELL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GIDYIHANELEIENGQVTGRVVGQIVNGQRKAELLRGIAAQEGISLEQVIAVGDGANDLP
CCCEEECCCEEECCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCC
MLGEAGLGIAFRAKPLVKQNAEQAISTLGLDGILYLIGVRDKDQAELLKGN
CCCCCCCCEEEECCHHHHCCHHHHHHHHCCCCEEEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA