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The map label for this gene is aroB [H]

Identifier: 110835092

GI number: 110835092

Start: 2548565

End: 2549644

Strand: Reverse

Name: aroB [H]

Synonym: ABO_2231

Alternate gene names: 110835092

Gene position: 2549644-2548565 (Counterclockwise)

Preceding gene: 110835093

Following gene: 110835091

Centisome position: 81.72

GC content: 54.81

Gene sequence:

>1080_bases
ATGCGCACACTTCAGGTGGCCTTGGCCGAGCGGAGTTACCCTATCCATATTGGGGCCGGCTTGCTGTCGTCTTTTCCCTT
AGCTGAGCAGGTTCGTGGCAACCAGGTGATGATCATCACCAACGAAACTATTGCGCCGCTGTATCTAGCCTCACTGGAGG
CGCACTTTTCTGCTATTCAGTGCGATACGCTCATTCTCCCCGATGGCGAAAAATTCAAAACCCTTGAAACTCTTGAAACC
CTTTTTGATGCTTTGATGGCCAAGCGCCATTCGCGCACCACAACACTGGTGGCGTTGGGCGGCGGCGTTGTTGGCGATAT
GGTGGGTTTTGCGGCGGCCTGCTATCAGCGGGGGGTGGATTTCATCCAGGTGCCAACGACTCTGCTGGCCCAGGTGGATT
CGTCCGTTGGCGGTAAGACCGCGGTCAACCATCCCCGTGGCAAGAACATGATTGGTGCCTTTCATCAGCCGCGCTTGGTT
CTGATTGATACCGACGTGTTGAACTCGCTGCCAGAGCGGGAATTGGCTGCAGGTTATGCGGAAGTGGTTAAGTATGGTCT
GATTCGTGACCCTAGTTTCTATCAGTGGCTGGAAACCAATAACGACAAGCTGTTGTCCAGAGATGAGGCGATCATTTCTG
AGGCGATCTTCCGTAGCTGCGAGAACAAGGCTCAGGTCGTTGCGGATGATGAAACCGAACAGGGTAACCGTGCGTTGCTG
AACCTGGGGCATACTTTTGGTCATGCCATTGAGACCGCCACCGGTTATAGCCAGTGGTTGCACGGTGAGGCGGTAGCGGT
GGGCATGTTGATGGCCATTCGCATGTCCGCTGAGTTGGGCTGGGTGCCGGCAGAGCTGGAGTCAAAAGTGGCCACTTTGT
TGTCTGCCTGGGGCTTGCCGGTGGCGGTTCCCGAAGGGATGACGCCGGAACAATTTATGGACCTAATGGCCTTGGATAAG
AAGGTTCATAATGGCCAGTTGCGCCTTGTGTTGCTGCGTGAGCTGGGTAAGGCTGTGGTAACGGCGGATTATGACGGCGC
GGCATTGCAAAAAACATTGGAGGCTTTTTGTGGAGCATGA

Upstream 100 bases:

>100_bases
TGACGTGCTCGCTTGTTTGGACTCTCAGCCACAAGGATAATGCAGGCAACTGTCGGGCTGGTGCTTGGCCTATTTTGCTG
AATTATCATTGGGAGCTGTA

Downstream 100 bases:

>100_bases
TGACGAGCGTTTCTATAGCGGTGCCTCGCGTGGGGACTTTCTGGATGCCATGACGGCCCACGCCGAGCAGGGCTCGGTGG
TCGCTATAGAGGGCGACACC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRTLQVALAERSYPIHIGAGLLSSFPLAEQVRGNQVMIITNETIAPLYLASLEAHFSAIQCDTLILPDGEKFKTLETLET
LFDALMAKRHSRTTTLVALGGGVVGDMVGFAAACYQRGVDFIQVPTTLLAQVDSSVGGKTAVNHPRGKNMIGAFHQPRLV
LIDTDVLNSLPERELAAGYAEVVKYGLIRDPSFYQWLETNNDKLLSRDEAIISEAIFRSCENKAQVVADDETEQGNRALL
NLGHTFGHAIETATGYSQWLHGEAVAVGMLMAIRMSAELGWVPAELESKVATLLSAWGLPVAVPEGMTPEQFMDLMALDK
KVHNGQLRLVLLRELGKAVVTADYDGAALQKTLEAFCGA

Sequences:

>Translated_359_residues
MRTLQVALAERSYPIHIGAGLLSSFPLAEQVRGNQVMIITNETIAPLYLASLEAHFSAIQCDTLILPDGEKFKTLETLET
LFDALMAKRHSRTTTLVALGGGVVGDMVGFAAACYQRGVDFIQVPTTLLAQVDSSVGGKTAVNHPRGKNMIGAFHQPRLV
LIDTDVLNSLPERELAAGYAEVVKYGLIRDPSFYQWLETNNDKLLSRDEAIISEAIFRSCENKAQVVADDETEQGNRALL
NLGHTFGHAIETATGYSQWLHGEAVAVGMLMAIRMSAELGWVPAELESKVATLLSAWGLPVAVPEGMTPEQFMDLMALDK
KVHNGQLRLVLLRELGKAVVTADYDGAALQKTLEAFCGA
>Mature_359_residues
MRTLQVALAERSYPIHIGAGLLSSFPLAEQVRGNQVMIITNETIAPLYLASLEAHFSAIQCDTLILPDGEKFKTLETLET
LFDALMAKRHSRTTTLVALGGGVVGDMVGFAAACYQRGVDFIQVPTTLLAQVDSSVGGKTAVNHPRGKNMIGAFHQPRLV
LIDTDVLNSLPERELAAGYAEVVKYGLIRDPSFYQWLETNNDKLLSRDEAIISEAIFRSCENKAQVVADDETEQGNRALL
NLGHTFGHAIETATGYSQWLHGEAVAVGMLMAIRMSAELGWVPAELESKVATLLSAWGLPVAVPEGMTPEQFMDLMALDK
KVHNGQLRLVLLRELGKAVVTADYDGAALQKTLEAFCGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=348, Percent_Identity=56.6091954022989, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320332, Length=313, Percent_Identity=37.6996805111821, Blast_Score=192, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38951; Mature: 38951

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLQVALAERSYPIHIGAGLLSSFPLAEQVRGNQVMIITNETIAPLYLASLEAHFSAIQ
CCCEEEEECCCCCCEEECCHHHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHEE
CDTLILPDGEKFKTLETLETLFDALMAKRHSRTTTLVALGGGVVGDMVGFAAACYQRGVD
ECEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
FIQVPTTLLAQVDSSVGGKTAVNHPRGKNMIGAFHQPRLVLIDTDVLNSLPERELAAGYA
EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCCHHHHHHHH
EVVKYGLIRDPSFYQWLETNNDKLLSRDEAIISEAIFRSCENKAQVVADDETEQGNRALL
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHE
NLGHTFGHAIETATGYSQWLHGEAVAVGMLMAIRMSAELGWVPAELESKVATLLSAWGLP
ECCHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
VAVPEGMTPEQFMDLMALDKKVHNGQLRLVLLRELGKAVVTADYDGAALQKTLEAFCGA
EECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRTLQVALAERSYPIHIGAGLLSSFPLAEQVRGNQVMIITNETIAPLYLASLEAHFSAIQ
CCCEEEEECCCCCCEEECCHHHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHEE
CDTLILPDGEKFKTLETLETLFDALMAKRHSRTTTLVALGGGVVGDMVGFAAACYQRGVD
ECEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
FIQVPTTLLAQVDSSVGGKTAVNHPRGKNMIGAFHQPRLVLIDTDVLNSLPERELAAGYA
EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCCHHHHHHHH
EVVKYGLIRDPSFYQWLETNNDKLLSRDEAIISEAIFRSCENKAQVVADDETEQGNRALL
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHE
NLGHTFGHAIETATGYSQWLHGEAVAVGMLMAIRMSAELGWVPAELESKVATLLSAWGLP
ECCHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
VAVPEGMTPEQFMDLMALDKKVHNGQLRLVLLRELGKAVVTADYDGAALQKTLEAFCGA
EECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA