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The map label for this gene is aroK [H]

Identifier: 110835093

GI number: 110835093

Start: 2549705

End: 2550196

Strand: Reverse

Name: aroK [H]

Synonym: ABO_2232

Alternate gene names: 110835093

Gene position: 2550196-2549705 (Counterclockwise)

Preceding gene: 110835094

Following gene: 110835092

Centisome position: 81.73

GC content: 58.54

Gene sequence:

>492_bases
ATGGGTGCGGGGAAAAGCACCTTGGGCAGGCATCTTGCTCAGGTGTTGGACCGCCCGTTTTTCGACTCTGATCGTGTAAT
CGAGGAGAAAACTGGCGCGGATATTCCCTGGATCTTCGATATGGAAGGTGAGGAGGGGTTTCGGCGGCGGGAACAAGATG
TGATTGACGAGCTAACCCGGGAGCCTGGCATCGTGCTGGCTACCGGCGGCGGGGTGGTGGTTACCCCGGAGAATCGAGCC
TTTCTTCATGAGCGCGGCTGTGTCGTCTACCTGTGGACACCGGTAGAGGTTCAGCTGGCCCGGACTCGCAATGACAAAGG
GCGCCCACTGCTGCAAACGGCAGATCCCAAGGCGCGGCTGGATGCCTTGTTCGCCGAGCGTGATCCGCTCTATCGGCAGG
TGGCTCATCATGTGGTCTCGACGGCATCAGGAAACCTGAAAAAAGTCGCGGATGACGTGCTCGCTTGTTTGGACTCTCAG
CCACAAGGATAA

Upstream 100 bases:

>100_bases
AAGAATTGCTGATCTTTATTACGCCACGGTTGATGAAGGATGCTTTGGCTAATCGGTGATCAAAACTAATTCTATTGTTC
CTTTAATTCTTGTCGGGCCT

Downstream 100 bases:

>100_bases
TGCAGGCAACTGTCGGGCTGGTGCTTGGCCTATTTTGCTGAATTATCATTGGGAGCTGTAATGCGCACACTTCAGGTGGC
CTTGGCCGAGCGGAGTTACC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MGAGKSTLGRHLAQVLDRPFFDSDRVIEEKTGADIPWIFDMEGEEGFRRREQDVIDELTREPGIVLATGGGVVVTPENRA
FLHERGCVVYLWTPVEVQLARTRNDKGRPLLQTADPKARLDALFAERDPLYRQVAHHVVSTASGNLKKVADDVLACLDSQ
PQG

Sequences:

>Translated_163_residues
MGAGKSTLGRHLAQVLDRPFFDSDRVIEEKTGADIPWIFDMEGEEGFRRREQDVIDELTREPGIVLATGGGVVVTPENRA
FLHERGCVVYLWTPVEVQLARTRNDKGRPLLQTADPKARLDALFAERDPLYRQVAHHVVSTASGNLKKVADDVLACLDSQ
PQG
>Mature_162_residues
GAGKSTLGRHLAQVLDRPFFDSDRVIEEKTGADIPWIFDMEGEEGFRRREQDVIDELTREPGIVLATGGGVVVTPENRAF
LHERGCVVYLWTPVEVQLARTRNDKGRPLLQTADPKARLDALFAERDPLYRQVAHHVVSTASGNLKKVADDVLACLDSQP
QG

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=160, Percent_Identity=55, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1786587, Length=141, Percent_Identity=36.8794326241135, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18105; Mature: 17973

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGKSTLGRHLAQVLDRPFFDSDRVIEEKTGADIPWIFDMEGEEGFRRREQDVIDELTR
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHC
EPGIVLATGGGVVVTPENRAFLHERGCVVYLWTPVEVQLARTRNDKGRPLLQTADPKARL
CCCEEEEECCCEEECCCCCEEHCCCCEEEEEECCCEEEEEECCCCCCCCCEECCCCHHHH
DALFAERDPLYRQVAHHVVSTASGNLKKVADDVLACLDSQPQG
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GAGKSTLGRHLAQVLDRPFFDSDRVIEEKTGADIPWIFDMEGEEGFRRREQDVIDELTR
CCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHC
EPGIVLATGGGVVVTPENRAFLHERGCVVYLWTPVEVQLARTRNDKGRPLLQTADPKARL
CCCEEEEECCCEEECCCCCEEHCCCCEEEEEECCCEEEEEECCCCCCCCCEECCCCHHHH
DALFAERDPLYRQVAHHVVSTASGNLKKVADDVLACLDSQPQG
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA