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The map label for this gene is pdxA [H]

Identifier: 110834908

GI number: 110834908

Start: 2336293

End: 2337300

Strand: Direct

Name: pdxA [H]

Synonym: ABO_2047

Alternate gene names: 110834908

Gene position: 2336293-2337300 (Clockwise)

Preceding gene: 110834907

Following gene: 110834909

Centisome position: 74.88

GC content: 61.01

Gene sequence:

>1008_bases
ATGCCTAGCTCGCCCTCCCAACCCATCGCCATCACTTACGGCGACCCCGCAGGAGTCGGGCCGGACCTAGTGCTATCTCT
GCTGGATACCTTCAGTGATGCCCCAATGGTCATCATCGGTGACCGCCAGGTACTCAGCGAACGAGCGCAACAATTAGGCC
TGACGGTGGCGTTAAGTGACTGGCAGCCGGGCGATCTACTACCAGTAGGCTCCCTGCCCGTATGGCACACCCCAGCCGGC
GCCCCTGTCATCGCTGGGCAACCGGACCCGGCCACCGCCGCCGGCACCGTGACCATGCTCACTCGTGCCGCTCAGGGCTG
CCTCAAAGGCACCTTCTCAGCTATGGTCACCGCCCCGGTGGCGAAAAACGTCATTTGCGACGGAGCCGACCCAGCGTTCA
CCGGCCATACTGAATTTCTCGCCGAACAGGCCGGGGTAAATCAGGTAGTAATGATGCTCACCGCGTCTCCCGGCGGGCAG
CCGCTTAGAGTAGCCTTGGCCACCACCCACCTGCCCCTAAGCCAGGTACCGGCAGCCATTACTCCAGATAGCCTGATGCG
CACCCTGACCATTCTGCGCGACGACCTGATCAGCAAGTACCGCATTACCGAACCGCGCATTATGGTACTGGGGCTCAATC
CTCACGCCGGCGAAGAGGGCCACCTGGGCCGTGAAGAATTGGATGTAATCATTCCCACGTTGAAACACCTACGCGCTAAG
GGCATGCAGCTCACCGGCCCTCTTCCCGCCGACACGGCTTTCCAGCCCCATTTACTTGAGCAACACGATGCGGTGCTTGC
CATGTATCATGACCAAGGCTTGCCGGTGCTCAAGTACGCTGGTTTTGGCGAAGCCATCAATATCACTCTGGGGCTGCCTT
TTATTCGCACCTCAGTGGACCATGGCACCGCCTTCGATCTGGCAGGCAACGGCACGGCCAGCGCCGGCAGCCTGATCGCC
GCCACGCGCCTAGCGTTAACCTTGGCAACACCGCAGCATAATGCCTGA

Upstream 100 bases:

>100_bases
CTTCTGCACAAGCGAGAGAGGCCCCTCTCCCGCTTGCGGGAGAAGGGGGAGGGAGAAAGCATCGGCGCTCGGCGTCCGGC
TTCAGGCCTTCTACTAATCC

Downstream 100 bases:

>100_bases
CCACACCAGCGCCCTTGCGTTGATTAAGTCACACCACCCGGCCTGACCTGAGATCCGCTATGAAAGAACATCGCACCCGT
AAACGCTTTGGCCAGCATTT

Product: pyridoxal phosphate biosynthetic protein PdxA

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPSSPSQPIAITYGDPAGVGPDLVLSLLDTFSDAPMVIIGDRQVLSERAQQLGLTVALSDWQPGDLLPVGSLPVWHTPAG
APVIAGQPDPATAAGTVTMLTRAAQGCLKGTFSAMVTAPVAKNVICDGADPAFTGHTEFLAEQAGVNQVVMMLTASPGGQ
PLRVALATTHLPLSQVPAAITPDSLMRTLTILRDDLISKYRITEPRIMVLGLNPHAGEEGHLGREELDVIIPTLKHLRAK
GMQLTGPLPADTAFQPHLLEQHDAVLAMYHDQGLPVLKYAGFGEAINITLGLPFIRTSVDHGTAFDLAGNGTASAGSLIA
ATRLALTLATPQHNA

Sequences:

>Translated_335_residues
MPSSPSQPIAITYGDPAGVGPDLVLSLLDTFSDAPMVIIGDRQVLSERAQQLGLTVALSDWQPGDLLPVGSLPVWHTPAG
APVIAGQPDPATAAGTVTMLTRAAQGCLKGTFSAMVTAPVAKNVICDGADPAFTGHTEFLAEQAGVNQVVMMLTASPGGQ
PLRVALATTHLPLSQVPAAITPDSLMRTLTILRDDLISKYRITEPRIMVLGLNPHAGEEGHLGREELDVIIPTLKHLRAK
GMQLTGPLPADTAFQPHLLEQHDAVLAMYHDQGLPVLKYAGFGEAINITLGLPFIRTSVDHGTAFDLAGNGTASAGSLIA
ATRLALTLATPQHNA
>Mature_334_residues
PSSPSQPIAITYGDPAGVGPDLVLSLLDTFSDAPMVIIGDRQVLSERAQQLGLTVALSDWQPGDLLPVGSLPVWHTPAGA
PVIAGQPDPATAAGTVTMLTRAAQGCLKGTFSAMVTAPVAKNVICDGADPAFTGHTEFLAEQAGVNQVVMMLTASPGGQP
LRVALATTHLPLSQVPAAITPDSLMRTLTILRDDLISKYRITEPRIMVLGLNPHAGEEGHLGREELDVIIPTLKHLRAKG
MQLTGPLPADTAFQPHLLEQHDAVLAMYHDQGLPVLKYAGFGEAINITLGLPFIRTSVDHGTAFDLAGNGTASAGSLIAA
TRLALTLATPQHNA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=53.3742331288344, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34970; Mature: 34838

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSPSQPIAITYGDPAGVGPDLVLSLLDTFSDAPMVIIGDRQVLSERAQQLGLTVALSD
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEECC
WQPGDLLPVGSLPVWHTPAGAPVIAGQPDPATAAGTVTMLTRAAQGCLKGTFSAMVTAPV
CCCCCEEEECCCCCEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKNVICDGADPAFTGHTEFLAEQAGVNQVVMMLTASPGGQPLRVALATTHLPLSQVPAAI
HHCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEECCCHHHCCCCC
TPDSLMRTLTILRDDLISKYRITEPRIMVLGLNPHAGEEGHLGREELDVIIPTLKHLRAK
CHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GMQLTGPLPADTAFQPHLLEQHDAVLAMYHDQGLPVLKYAGFGEAINITLGLPFIRTSVD
CCEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCC
HGTAFDLAGNGTASAGSLIAATRLALTLATPQHNA
CCCEEEECCCCCCCCCHHHHEEEEEEEEECCCCCC
>Mature Secondary Structure 
PSSPSQPIAITYGDPAGVGPDLVLSLLDTFSDAPMVIIGDRQVLSERAQQLGLTVALSD
CCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEECC
WQPGDLLPVGSLPVWHTPAGAPVIAGQPDPATAAGTVTMLTRAAQGCLKGTFSAMVTAPV
CCCCCEEEECCCCCEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKNVICDGADPAFTGHTEFLAEQAGVNQVVMMLTASPGGQPLRVALATTHLPLSQVPAAI
HHCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEECCCHHHCCCCC
TPDSLMRTLTILRDDLISKYRITEPRIMVLGLNPHAGEEGHLGREELDVIIPTLKHLRAK
CHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GMQLTGPLPADTAFQPHLLEQHDAVLAMYHDQGLPVLKYAGFGEAINITLGLPFIRTSVD
CCEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCC
HGTAFDLAGNGTASAGSLIAATRLALTLATPQHNA
CCCEEEECCCCCCCCCHHHHEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA