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The map label for this gene is surA

Identifier: 110834907

GI number: 110834907

Start: 2334820

End: 2336127

Strand: Direct

Name: surA

Synonym: ABO_2046

Alternate gene names: 110834907

Gene position: 2334820-2336127 (Clockwise)

Preceding gene: 110834906

Following gene: 110834908

Centisome position: 74.83

GC content: 55.96

Gene sequence:

>1308_bases
ATGATTAATAAAACGCTGCACACAAAACACACCCTACTTGGCCTACTCGCCATGGCTGTGCTGATGATACCGGTCTGGAG
TCAGGCCAAAGTGCAGATGCTTGATCGCATAGTGGCGGTGGTTAACGATGGTGCCATCATGGCGAGTGAGCTGGATGAGC
GTATCAACACTATCGCCCTGCAGTTTCAAGAAAAAGGGCAGCAACTGCCGTCTCCAGCCATCCTCCGCGAGCAGGTGCTC
GATCGCATGATCCTGGAGCGTCTGCAGCTGCAACTGGCCGAGCGCGCCGGGATCAAAGTCGACGAAGCCAGCCTCAATGA
GGCGCTGGCGGGCATTGCTCGTCAAAACGACATGAGCCTGGAAGACTTCGCCGCAACCCTACGTGAAGATGGCTACAGCT
GGACCCAGTTCCGCGAACAAATTCGTCAAGACATGGTGATCTCCCGCTTGCAGCAACGCAGCGTGGCCTCACGCATTCAG
ATCACCGACCGAGAAGTAGACCGCTTCCTAAGCTCTGAACTGGGCAAACAAATGTTTCAGGAAGACTTTCGCTTAGGGCA
CATTTTGATCCGCGTACCCTCTGAAGCCCGGCCGCAGCAGATTAGCCAGGCCCGCGCCAAAGCCAAAGAGATCATCGAAC
GACTCGAAGCCGGCAGTGACTTCCAGCAGCTGGCCATCGCCCTATCCGATGGCCCCAACGCCCTTGAGGGTGGCGACCTC
GGCTGGCGCCCAGCCGCACAGTGGCCCACCCTTTTTGCAGAAAATGCCATCAACCTGAAAAAAGGCGAATTTTCCCAGCC
TCTACGTTCTGGTGCCGGCTTTCATATCCTAAAAATGATCGATCGCAAGGGCGGCGCTGAAAAAGTGGTCACCCAATATC
ACGTTCGCCATGTGCTGATAAAAGCCGATGCGCTCACCAGTGCTGAGCAGGCCCAACAACGAGCGATTCGCCTTCATGAC
GAGGTCGCCGCAGGTAAACGTCAATTTAAGGAAACCGCCGCCGAATTTTCCGACGACCCAGGCAGCGCTCGCAATGGCGG
CGAACTGGGCTGGGTCAACAAAGGCGAAATGGTCCCCGAATTTGAACAAGTGATGCTCAATACCCCAGTGGGCGAGCTAT
CCCCAGTGTTCGAAAGCCAATTCGGCTGGCACTTCTTGCGCGTAGATGACATCCGCGATGCAGATATGAGCACCGAGTTC
CGCCGCATGCAGGCCACCCAGGCACTGCAGAAACGCCGCTTTGAAGAAGAGCTGGAAACGTGGGTGCAAGAAAAACGCAG
CGAGTCCTATGTGGATATTCGGTTGTGA

Upstream 100 bases:

>100_bases
AGCACAATCTGGTTCCAAATCCAGATGATCGGCTTAGGCGGCTTTGGCGGCCAAGTGGATTCCCTGCTGGAGCGCAGCAT
TCCGGGATACAGGAGACAGT

Downstream 100 bases:

>100_bases
AAAATCCAGCGCCGAATACCCGATGCCAGCCGGCGCTTAGCCGTGCTAAAACACAACTCCATTCCCTTCTGCACAAGCGA
GAGAGGCCCCTCTCCCGCTT

Product: survival protein SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIALQFQEKGQQLPSPAILREQVL
DRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSLEDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQ
ITDREVDRFLSSELGKQMFQEDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDL
GWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLIKADALTSAEQAQQRAIRLHD
EVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPEFEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEF
RRMQATQALQKRRFEEELETWVQEKRSESYVDIRL

Sequences:

>Translated_435_residues
MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIALQFQEKGQQLPSPAILREQVL
DRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSLEDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQ
ITDREVDRFLSSELGKQMFQEDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDL
GWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLIKADALTSAEQAQQRAIRLHD
EVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPEFEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEF
RRMQATQALQKRRFEEELETWVQEKRSESYVDIRL
>Mature_435_residues
MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIALQFQEKGQQLPSPAILREQVL
DRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSLEDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQ
ITDREVDRFLSSELGKQMFQEDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDL
GWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLIKADALTSAEQAQQRAIRLHD
EVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPEFEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEF
RRMQATQALQKRRFEEELETWVQEKRSESYVDIRL

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=420, Percent_Identity=35.9523809523809, Blast_Score=281, Evalue=6e-77,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_ALCBS (Q0VMV4)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693766.1
- ProteinModelPortal:   Q0VMV4
- SMR:   Q0VMV4
- STRING:   Q0VMV4
- GeneID:   4211982
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2046
- NMPDR:   fig|393595.12.peg.2048
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- PhylomeDB:   Q0VMV4
- BioCyc:   ABOR393595:ABO_2046-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 49313; Mature: 49313

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QFQEKGQQLPSPAILREQVLDRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCH
EDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQITDREVDRFLSSELGKQMFQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDL
HHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
GWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLI
CCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
KADALTSAEQAQQRAIRLHDEVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
FEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEFRRMQATQALQKRRFEEELET
HHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WVQEKRSESYVDIRL
HHHHHCCCCCEEEEC
>Mature Secondary Structure
MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QFQEKGQQLPSPAILREQVLDRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCH
EDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQITDREVDRFLSSELGKQMFQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDL
HHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
GWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLI
CCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
KADALTSAEQAQQRAIRLHDEVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
FEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEFRRMQATQALQKRRFEEELET
HHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WVQEKRSESYVDIRL
HHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA