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The map label for this gene is lptD

Identifier: 110834906

GI number: 110834906

Start: 2332548

End: 2334827

Strand: Direct

Name: lptD

Synonym: ABO_2045

Alternate gene names: 110834906

Gene position: 2332548-2334827 (Clockwise)

Preceding gene: 110834901

Following gene: 110834907

Centisome position: 74.76

GC content: 57.11

Gene sequence:

>2280_bases
ATGCCACTGCCCATACCTCGATTATTGATTCCAGCCCTGCTGCTTGCCTCAGGGGCTAGCCTTGCGGAAAACGACCTGAA
CTGGGTTGACCGCGAACAAATGGCCACGTTTCCTGCTGTCCAGCAGCGGGAGATACCCGACTGGTGCGCGGGGATTTATT
ATAACCCCCATGTCGGCATGCCCGTGGAGGGCAGTGATACAGTGATCACCGCCGATCATTCCACGCTTACCCAAGACGGC
CTAATCAAACTGGACGGCGATGTCCTGATTGAACAGCCCGGGCGCCGCATTACCACCGATATTGCCGAGCTTGATCAAGC
CACCGGCAAGTTTGAGCTGGAAAACGGCATGCGCATGGAAAGCGATCAGGCGACCTTTATCGCCGAAAACATGAGCGGCC
AAACACGACGCAAGGAAGGTAGCCTGCAAGGGGTACGCTACTCTCTGTTCGACACTAGCGCCCGCGGCAGCGCCAATTAT
ATTTTCCTGAAACAAAATACCACCACCATCACCCACGGCACCTATACCACCTGTGCCCCCGGCTCCAACGGCTGGGTTAT
GCAAGGCGATCGTATTTTCCTGGACCGTGATAAGGGCTGGGGTGAAGCCAACAACGTAGTGCTCAAGGTAAAGAGCGTAC
CGATCTTCTGGCTACCCTGGATGACCTTCCCGATCGATGATCGGCGCAAGAGCGGCCTGCTGTTTCCCACCCTCTCCGTG
GGTGATAGCAGCGGGCTGGATATTTCCCAGCCCATTTATCTGAACCTGCACCCACAACTCGACGCCACCATTTCTCCTCG
CTATATCGATGGTCGAGGCAGCGGTCTGGACAGCGAAATGCGCTACCTGTCGCGCTGGGGCGAAGGCAGCCTCAGTTACG
GGGTACTGTTCAACGACCGCAAGTTCGACAATGAAAACCGCCAAGTCGGTCGCTGGACTCACAATGGCGACATTAACCGC
TGGAGCCTGGAGACGGATTTCACCTACGTCTCCGATGACTTCTATTTCAAGGATCTGGACACCGGACTAGAAATCAGCTC
ACAAACCCACCTGCCCCGGCTCGGGGAGGCCCGCTATTACGGCCGCACTTGGCAGGTATTGGGCCGGCTGCAATCCTGGC
AGACCATTGACCCGACCCTCGACGACGCCGACCTGCCCTACCGGCGCCTACCCCAGCTACAATTAACCGGTGACCCAACC
CTAGTAGGGCCCGTGAAAGGCTTATGGCTATCAGACATCACAGCCTTCGGCCGAAGTGACTCTGATGACAGCGGCAAAGC
CACCGGCCTGCGTGGCCACATGGCCCCGGCCTTGACCATGCGCCTGCAAAACTCCTGGGGCTATGTGGAGCCGCGGGCCC
GGCTGTACCACACCCAGTATCGGCTCGATAGCGTTGACGCCAACGAAGAAGACAACCCTGACCTGACAACCTGGGGGGCC
AGCTTAGATTCTGGCCTGTTCTTCGAGCGCGCGGGCAATTGGTTCGGTTCCAGTTTTACCCAAACGCTGGAGCCGCGTCT
GTTCCTGAACAAAGTCGCCTACGAAGACCAAAGCGAACTACCCAACTTCGATTCCGGCGAGCTGACGTTCTCTTATAACT
CGCTGTTCCGGGAAAACCGCTTCATCGGCTACGACCGCATCGGCGACGAAGAGAAATTGGCGGTAGGCCTAACCAGTCGC
TTCCTGCATGATGGCACTGGCCGCGAACAACTACGCCTACGAGTGGCGCAAGGCTTCTACTTTGAGGACCGCAAAGTGGT
CACCGAGCGGGCCGTGGAAGACCCCACCGATGACCAAACACCGGTTATTGGCGATGCACGCTGGAACTTTGCACAGGATT
GGTACCTCTACTCTGAAGGCCAGTGGGATATAGAAGAAAACAAACGCGAGCGCTCCAACTTTCAAATTGGCTATAACGAC
CGCGAACGGCGCGTCGTCAATGTGGGTTATCACGACCGCCCGGCAGACAGTATCCGCGAATCGGAAGTCAGTGCCATTTT
GCCCGTTCACCGGCATTGGCGGCTGATTGGCCGCTGGATGTACGACCTAGATAACCAGCGTTCGCTGGAAACCATGGCCG
GTACCGAATACCGCAATTGCTGCTGGAAATTGCGACTACTTAGCCAGCGCGAGCTGATGGATGACAATGGCGACGGCAAC
CTAGAGGCGGACAGCACAATCTGGTTCCAAATCCAGATGATCGGCTTAGGCGGCTTTGGCGGCCAAGTGGATTCCCTGCT
GGAGCGCAGCATTCCGGGATACAGGAGACAGTATGATTAA

Upstream 100 bases:

>100_bases
AGGCTGCATTGCCTTCCTTGTTAGATTACACTGCCGCTTTTGGTGGAACGGAAAGCCCGGCCCGCCATAAAACGGCCTTT
TTACCTGTTCTGAGCAGCTG

Downstream 100 bases:

>100_bases
TAAAACGCTGCACACAAAACACACCCTACTTGGCCTACTCGCCATGGCTGTGCTGATGATACCGGTCTGGAGTCAGGCCA
AAGTGCAGATGCTTGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MPLPIPRLLIPALLLASGASLAENDLNWVDREQMATFPAVQQREIPDWCAGIYYNPHVGMPVEGSDTVITADHSTLTQDG
LIKLDGDVLIEQPGRRITTDIAELDQATGKFELENGMRMESDQATFIAENMSGQTRRKEGSLQGVRYSLFDTSARGSANY
IFLKQNTTTITHGTYTTCAPGSNGWVMQGDRIFLDRDKGWGEANNVVLKVKSVPIFWLPWMTFPIDDRRKSGLLFPTLSV
GDSSGLDISQPIYLNLHPQLDATISPRYIDGRGSGLDSEMRYLSRWGEGSLSYGVLFNDRKFDNENRQVGRWTHNGDINR
WSLETDFTYVSDDFYFKDLDTGLEISSQTHLPRLGEARYYGRTWQVLGRLQSWQTIDPTLDDADLPYRRLPQLQLTGDPT
LVGPVKGLWLSDITAFGRSDSDDSGKATGLRGHMAPALTMRLQNSWGYVEPRARLYHTQYRLDSVDANEEDNPDLTTWGA
SLDSGLFFERAGNWFGSSFTQTLEPRLFLNKVAYEDQSELPNFDSGELTFSYNSLFRENRFIGYDRIGDEEKLAVGLTSR
FLHDGTGREQLRLRVAQGFYFEDRKVVTERAVEDPTDDQTPVIGDARWNFAQDWYLYSEGQWDIEENKRERSNFQIGYND
RERRVVNVGYHDRPADSIRESEVSAILPVHRHWRLIGRWMYDLDNQRSLETMAGTEYRNCCWKLRLLSQRELMDDNGDGN
LEADSTIWFQIQMIGLGGFGGQVDSLLERSIPGYRRQYD

Sequences:

>Translated_759_residues
MPLPIPRLLIPALLLASGASLAENDLNWVDREQMATFPAVQQREIPDWCAGIYYNPHVGMPVEGSDTVITADHSTLTQDG
LIKLDGDVLIEQPGRRITTDIAELDQATGKFELENGMRMESDQATFIAENMSGQTRRKEGSLQGVRYSLFDTSARGSANY
IFLKQNTTTITHGTYTTCAPGSNGWVMQGDRIFLDRDKGWGEANNVVLKVKSVPIFWLPWMTFPIDDRRKSGLLFPTLSV
GDSSGLDISQPIYLNLHPQLDATISPRYIDGRGSGLDSEMRYLSRWGEGSLSYGVLFNDRKFDNENRQVGRWTHNGDINR
WSLETDFTYVSDDFYFKDLDTGLEISSQTHLPRLGEARYYGRTWQVLGRLQSWQTIDPTLDDADLPYRRLPQLQLTGDPT
LVGPVKGLWLSDITAFGRSDSDDSGKATGLRGHMAPALTMRLQNSWGYVEPRARLYHTQYRLDSVDANEEDNPDLTTWGA
SLDSGLFFERAGNWFGSSFTQTLEPRLFLNKVAYEDQSELPNFDSGELTFSYNSLFRENRFIGYDRIGDEEKLAVGLTSR
FLHDGTGREQLRLRVAQGFYFEDRKVVTERAVEDPTDDQTPVIGDARWNFAQDWYLYSEGQWDIEENKRERSNFQIGYND
RERRVVNVGYHDRPADSIRESEVSAILPVHRHWRLIGRWMYDLDNQRSLETMAGTEYRNCCWKLRLLSQRELMDDNGDGN
LEADSTIWFQIQMIGLGGFGGQVDSLLERSIPGYRRQYD
>Mature_758_residues
PLPIPRLLIPALLLASGASLAENDLNWVDREQMATFPAVQQREIPDWCAGIYYNPHVGMPVEGSDTVITADHSTLTQDGL
IKLDGDVLIEQPGRRITTDIAELDQATGKFELENGMRMESDQATFIAENMSGQTRRKEGSLQGVRYSLFDTSARGSANYI
FLKQNTTTITHGTYTTCAPGSNGWVMQGDRIFLDRDKGWGEANNVVLKVKSVPIFWLPWMTFPIDDRRKSGLLFPTLSVG
DSSGLDISQPIYLNLHPQLDATISPRYIDGRGSGLDSEMRYLSRWGEGSLSYGVLFNDRKFDNENRQVGRWTHNGDINRW
SLETDFTYVSDDFYFKDLDTGLEISSQTHLPRLGEARYYGRTWQVLGRLQSWQTIDPTLDDADLPYRRLPQLQLTGDPTL
VGPVKGLWLSDITAFGRSDSDDSGKATGLRGHMAPALTMRLQNSWGYVEPRARLYHTQYRLDSVDANEEDNPDLTTWGAS
LDSGLFFERAGNWFGSSFTQTLEPRLFLNKVAYEDQSELPNFDSGELTFSYNSLFRENRFIGYDRIGDEEKLAVGLTSRF
LHDGTGREQLRLRVAQGFYFEDRKVVTERAVEDPTDDQTPVIGDARWNFAQDWYLYSEGQWDIEENKRERSNFQIGYNDR
ERRVVNVGYHDRPADSIRESEVSAILPVHRHWRLIGRWMYDLDNQRSLETMAGTEYRNCCWKLRLLSQRELMDDNGDGNL
EADSTIWFQIQMIGLGGFGGQVDSLLERSIPGYRRQYD

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=755, Percent_Identity=26.3576158940397, Blast_Score=256, Evalue=4e-69,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_ALCBS (Q0VMV5)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693765.1
- STRING:   Q0VMV5
- GeneID:   4213880
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2045
- NMPDR:   fig|393595.12.peg.2047
- eggNOG:   COG1452
- OMA:   TPYYWNI
- PhylomeDB:   Q0VMV5
- BioCyc:   ABOR393595:ABO_2045-MONOMER
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543

Pfam domain/function: PF03968 OstA; PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 86637; Mature: 86506

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPIPRLLIPALLLASGASLAENDLNWVDREQMATFPAVQQREIPDWCAGIYYNPHVGM
CCCCCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCCCHHHCCCCHHHHCCEECCCCCC
PVEGSDTVITADHSTLTQDGLIKLDGDVLIEQPGRRITTDIAELDQATGKFELENGMRME
CCCCCCCEEEECCCCCCCCCEEEECCCEEEECCCCEEHHHHHHHHHCCCCEEECCCCEEC
SDQATFIAENMSGQTRRKEGSLQGVRYSLFDTSARGSANYIFLKQNTTTITHGTYTTCAP
CCCCEEEEECCCCCCHHCCCCCCCEEEEEEECCCCCCCCEEEEECCCEEEECCCEEEECC
GSNGWVMQGDRIFLDRDKGWGEANNVVLKVKSVPIFWLPWMTFPIDDRRKSGLLFPTLSV
CCCCEEEECCEEEEECCCCCCCCCCEEEEEECCCEEEECCEECCCCCCCCCCEEEEEEEC
GDSSGLDISQPIYLNLHPQLDATISPRYIDGRGSGLDSEMRYLSRWGEGSLSYGVLFNDR
CCCCCCCCCCCEEEEECCCCCCEECCEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCC
KFDNENRQVGRWTHNGDINRWSLETDFTYVSDDFYFKDLDTGLEISSQTHLPRLGEARYY
CCCCCCCEECCEECCCCCEEEEEECCCEEEECCEEEEECCCCCEECCCCCCCCCCCCHHC
GRTWQVLGRLQSWQTIDPTLDDADLPYRRLPQLQLTGDPTLVGPVKGLWLSDITAFGRSD
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCEEECCCCCEECCCCCCHHHHHHHHCCCC
SDDSGKATGLRGHMAPALTMRLQNSWGYVEPRARLYHTQYRLDSVDANEEDNPDLTTWGA
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCCCCCCEEEECC
SLDSGLFFERAGNWFGSSFTQTLEPRLFLNKVAYEDQSELPNFDSGELTFSYNSLFRENR
CCCCCEEHHHCCCCCCCCHHHHCCCHHHHHHHHCCCHHHCCCCCCCEEEEEHHHHHHCCC
FIGYDRIGDEEKLAVGLTSRFLHDGTGREQLRLRVAQGFYFEDRKVVTERAVEDPTDDQT
CCCCCCCCCCCCEEEEHHHHHHHCCCCHHHEEEEEECCEEECCCHHHHHHHCCCCCCCCC
PVIGDARWNFAQDWYLYSEGQWDIEENKRERSNFQIGYNDRERRVVNVGYHDRPADSIRE
CEEECCCCCCEECEEEEECCCCCHHHHHHHCCCEEECCCCCCCEEEECCCCCCCHHHHHH
SEVSAILPVHRHWRLIGRWMYDLDNQRSLETMAGTEYRNCCWKLRLLSQRELMDDNGDGN
HHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LEADSTIWFQIQMIGLGGFGGQVDSLLERSIPGYRRQYD
EECCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PLPIPRLLIPALLLASGASLAENDLNWVDREQMATFPAVQQREIPDWCAGIYYNPHVGM
CCCCHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCCCHHHCCCCHHHHCCEECCCCCC
PVEGSDTVITADHSTLTQDGLIKLDGDVLIEQPGRRITTDIAELDQATGKFELENGMRME
CCCCCCCEEEECCCCCCCCCEEEECCCEEEECCCCEEHHHHHHHHHCCCCEEECCCCEEC
SDQATFIAENMSGQTRRKEGSLQGVRYSLFDTSARGSANYIFLKQNTTTITHGTYTTCAP
CCCCEEEEECCCCCCHHCCCCCCCEEEEEEECCCCCCCCEEEEECCCEEEECCCEEEECC
GSNGWVMQGDRIFLDRDKGWGEANNVVLKVKSVPIFWLPWMTFPIDDRRKSGLLFPTLSV
CCCCEEEECCEEEEECCCCCCCCCCEEEEEECCCEEEECCEECCCCCCCCCCEEEEEEEC
GDSSGLDISQPIYLNLHPQLDATISPRYIDGRGSGLDSEMRYLSRWGEGSLSYGVLFNDR
CCCCCCCCCCCEEEEECCCCCCEECCEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCC
KFDNENRQVGRWTHNGDINRWSLETDFTYVSDDFYFKDLDTGLEISSQTHLPRLGEARYY
CCCCCCCEECCEECCCCCEEEEEECCCEEEECCEEEEECCCCCEECCCCCCCCCCCCHHC
GRTWQVLGRLQSWQTIDPTLDDADLPYRRLPQLQLTGDPTLVGPVKGLWLSDITAFGRSD
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCEEECCCCCEECCCCCCHHHHHHHHCCCC
SDDSGKATGLRGHMAPALTMRLQNSWGYVEPRARLYHTQYRLDSVDANEEDNPDLTTWGA
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCCCCCCEEEECC
SLDSGLFFERAGNWFGSSFTQTLEPRLFLNKVAYEDQSELPNFDSGELTFSYNSLFRENR
CCCCCEEHHHCCCCCCCCHHHHCCCHHHHHHHHCCCHHHCCCCCCCEEEEEHHHHHHCCC
FIGYDRIGDEEKLAVGLTSRFLHDGTGREQLRLRVAQGFYFEDRKVVTERAVEDPTDDQT
CCCCCCCCCCCCEEEEHHHHHHHCCCCHHHEEEEEECCEEECCCHHHHHHHCCCCCCCCC
PVIGDARWNFAQDWYLYSEGQWDIEENKRERSNFQIGYNDRERRVVNVGYHDRPADSIRE
CEEECCCCCCEECEEEEECCCCCHHHHHHHCCCEEECCCCCCCEEEECCCCCCCHHHHHH
SEVSAILPVHRHWRLIGRWMYDLDNQRSLETMAGTEYRNCCWKLRLLSQRELMDDNGDGN
HHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LEADSTIWFQIQMIGLGGFGGQVDSLLERSIPGYRRQYD
EECCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA