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The map label for this gene is fis [C]

Identifier: 110834875

GI number: 110834875

Start: 2300567

End: 2300899

Strand: Direct

Name: fis [C]

Synonym: ABO_2014

Alternate gene names: 110834875

Gene position: 2300567-2300899 (Clockwise)

Preceding gene: 110834874

Following gene: 110834876

Centisome position: 73.73

GC content: 53.75

Gene sequence:

>333_bases
ATGACCCTTTCTTCAGTTAACACAGCCGCTGCACGGACACTTACTGAAATGAACACCGCTGAAGCACGAAAGCAGCCGCA
TCTTACTATTGCGCGCAGCGAAACCCACGACACGCTGCGCAATTGTGTGCGACGTTCGCTAAACGATTATTTCAACCAGC
TGGACGGCGAAGCCGTGAGCGAGCTCTACCCGATGGTGCTGGCTGAAATGGAAATTCCCCTGCTTGAGAAAGTGCTCGAG
TACACCCGTGGTAACCAGACCAAAGCCGCTGAGCTACTGGGCCTGAACCGCGGCACTCTGCGCAAGAAACTCAAGCAGTA
CGGTCTATTGTAA

Upstream 100 bases:

>100_bases
TCGAGCAGTTTTTCCAACAGATAAGCGCCACTACCGACCGAGTTCGCTTCGGTCGTTATGGCGAGGTGTCTGCCCGGAAG
AAAAACGGAGCCCTGGCCGC

Downstream 100 bases:

>100_bases
TACAGACCCGTAACACCAAGGGCAGTGACCACACTGCCCTTTTTTTGTTTCTAGCCCTCGTATTAATTAAGACTTCGCAA
CTTGGTGAAACCCCATGAGC

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MTLSSVNTAAARTLTEMNTAEARKQPHLTIARSETHDTLRNCVRRSLNDYFNQLDGEAVSELYPMVLAEMEIPLLEKVLE
YTRGNQTKAAELLGLNRGTLRKKLKQYGLL

Sequences:

>Translated_110_residues
MTLSSVNTAAARTLTEMNTAEARKQPHLTIARSETHDTLRNCVRRSLNDYFNQLDGEAVSELYPMVLAEMEIPLLEKVLE
YTRGNQTKAAELLGLNRGTLRKKLKQYGLL
>Mature_109_residues
TLSSVNTAAARTLTEMNTAEARKQPHLTIARSETHDTLRNCVRRSLNDYFNQLDGEAVSELYPMVLAEMEIPLLEKVLEY
TRGNQTKAAELLGLNRGTLRKKLKQYGLL

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=75, Percent_Identity=58.6666666666667, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 12436; Mature: 12305

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSSVNTAAARTLTEMNTAEARKQPHLTIARSETHDTLRNCVRRSLNDYFNQLDGEAVS
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ELYPMVLAEMEIPLLEKVLEYTRGNQTKAAELLGLNRGTLRKKLKQYGLL
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLSSVNTAAARTLTEMNTAEARKQPHLTIARSETHDTLRNCVRRSLNDYFNQLDGEAVS
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ELYPMVLAEMEIPLLEKVLEYTRGNQTKAAELLGLNRGTLRKKLKQYGLL
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]