Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 110834774

GI number: 110834774

Start: 2189847

End: 2191400

Strand: Direct

Name: sglT [H]

Synonym: ABO_1913

Alternate gene names: 110834774

Gene position: 2189847-2191400 (Clockwise)

Preceding gene: 110834773

Following gene: 110834777

Centisome position: 70.18

GC content: 55.92

Gene sequence:

>1554_bases
ATGACTCTGGCAATCGCTGACTGGATTGTCCTTGCTGGGTACCTTTGTATCGTGCTGGGCATCGGTATCTATTTCTCACG
CCGCAACACCAATACCGAAGAATATTTTGTAGGCGGTCGCCGTTTTCGCGGCTGGGTAATAGGTCTGTCATTAGTAGGCA
CATCCATCAGCTCCATTACCTTCTTGGCCTATCCCGCCGACGCCTTCCTGACCGACTGGTTACGCTACCTACCTAACCTG
GCCCTACTGCCTGCCATGCTGGTGGCAGCTTTCGTTTTTTTGCCTTTTTTTCGGCGCGAAAATATGACCAGCGCCTATGA
ATTCCTCGAGTTACGCTATGGTCCATCCATCCGAGTATATGGTGCCATTGCGTTTCTGGTGGCGCAGTTGGTGCGCCTAG
CCATGATCCTGTGGCTGCTCTCTCTTTTGATACAACAAGTCACCGATCTAACACCCACCACCGCCATTATTCTAGGTGGG
TTTTTTGTTGGCTTTTACACCGTCATCGGAGGTATTGATGCGGTAATCTGGACCGATGTGCTGCAAACCGTCATTTTGTT
ACTGGGCGGCCTCGTCTGCCTGTGGGTGATTCTCGAGGCGCTGCCCGGCGGGCTCAACCAAGTGTTCGAACAAGCAGGTC
AGGCCGGCAAGTTTGCCCTGGCGCCCTGGGAAAACGGTGCTCCCGCAGAGACCTCTTGGTCGTTCTCGCTGAGCGAAAAG
ACCGCCACCATGATGCTGTTGATCGGCCTCACCAACTGGCTCACAGAATACTCCAGCAACCAGAACACCGTGCAACGGTA
TTGCGCCTCCCAATCCACTAAGGAAGCGCGTCGCGGGCTCTGGGTATACCTATTCACCGCCCTGCCTATCTGGGCGTTCT
ACATGCTATTGGGCACGGCCCTGTGGGTGTTCTTTCAGGTTTATCCGGACGCCCAGGCAAGCGCGATTCTGACCGGTGAA
ACTCGGGCTGAAACTCTGATGCCCCATTTCATTACCGGCTACCTGCCCGCTGGCGTGGCCGGGCTGGTGATTGCAGCAGC
TCTGGCCGCCGCCATGAGCTCACTGGATTCCAGCATCAACTCCATCACTACCGTTAGCGTGGTTGACCTGTATCGCCGTC
ATCTGCGTCCTGGCCGCGATGATCGCCACTACCTAAAAGTGGCCTGGGCCATCGCCGCCGCCGTCACGGGAGTCATGATT
CTCGGAGCGCTGTGGCTAAATCAGGCTGATACCAAAACACTACAAGACACGTCAACCATCCTAGTGTCACTGCTTGGCGG
GGGAATGCTAGGGTTATATTTGCTGGGCTTTTTCAGCAAGAAGGGCAATGCGCGGGCCGCTTGGGTGGGGATTGGTTGCA
CCCTGGTATTCACTAGCTGGACCATTCTTACCAACAACCAGCTTTTACCGGAGGCACTAAGCGCCCCCTTTGACCTGTAT
TACACCGGACTGATTGGCAATGTGCTGATGTTTCTGGTCGGCTACGTGGTGGCTTTGCTCTGGCCTGCAGCCTCGGTGGC
GCCGGTTTCACCCCAGCCCGCTGCCGAGGGCTGA

Upstream 100 bases:

>100_bases
GAACAATAAAACAACCTAAGTCGCATCATGCGGCACGCGCAGCAGGCTGCACTCAGCGGCGTGTTGCGCGCCGCCTGTTG
CCTGAAGCGGAATAACAATA

Downstream 100 bases:

>100_bases
GTCGATGACTGCTGCGCGAGTAGAGCCCTCGCGCTCAGCAGCCGATCGCGTAGCAACCAACCCACCGCCCAACACACCAG
CCAAGGGTCCATCAGGTAAT

Product: sodium solute transporter family protein

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTLAIADWIVLAGYLCIVLGIGIYFSRRNTNTEEYFVGGRRFRGWVIGLSLVGTSISSITFLAYPADAFLTDWLRYLPNL
ALLPAMLVAAFVFLPFFRRENMTSAYEFLELRYGPSIRVYGAIAFLVAQLVRLAMILWLLSLLIQQVTDLTPTTAIILGG
FFVGFYTVIGGIDAVIWTDVLQTVILLLGGLVCLWVILEALPGGLNQVFEQAGQAGKFALAPWENGAPAETSWSFSLSEK
TATMMLLIGLTNWLTEYSSNQNTVQRYCASQSTKEARRGLWVYLFTALPIWAFYMLLGTALWVFFQVYPDAQASAILTGE
TRAETLMPHFITGYLPAGVAGLVIAAALAAAMSSLDSSINSITTVSVVDLYRRHLRPGRDDRHYLKVAWAIAAAVTGVMI
LGALWLNQADTKTLQDTSTILVSLLGGGMLGLYLLGFFSKKGNARAAWVGIGCTLVFTSWTILTNNQLLPEALSAPFDLY
YTGLIGNVLMFLVGYVVALLWPAASVAPVSPQPAAEG

Sequences:

>Translated_517_residues
MTLAIADWIVLAGYLCIVLGIGIYFSRRNTNTEEYFVGGRRFRGWVIGLSLVGTSISSITFLAYPADAFLTDWLRYLPNL
ALLPAMLVAAFVFLPFFRRENMTSAYEFLELRYGPSIRVYGAIAFLVAQLVRLAMILWLLSLLIQQVTDLTPTTAIILGG
FFVGFYTVIGGIDAVIWTDVLQTVILLLGGLVCLWVILEALPGGLNQVFEQAGQAGKFALAPWENGAPAETSWSFSLSEK
TATMMLLIGLTNWLTEYSSNQNTVQRYCASQSTKEARRGLWVYLFTALPIWAFYMLLGTALWVFFQVYPDAQASAILTGE
TRAETLMPHFITGYLPAGVAGLVIAAALAAAMSSLDSSINSITTVSVVDLYRRHLRPGRDDRHYLKVAWAIAAAVTGVMI
LGALWLNQADTKTLQDTSTILVSLLGGGMLGLYLLGFFSKKGNARAAWVGIGCTLVFTSWTILTNNQLLPEALSAPFDLY
YTGLIGNVLMFLVGYVVALLWPAASVAPVSPQPAAEG
>Mature_516_residues
TLAIADWIVLAGYLCIVLGIGIYFSRRNTNTEEYFVGGRRFRGWVIGLSLVGTSISSITFLAYPADAFLTDWLRYLPNLA
LLPAMLVAAFVFLPFFRRENMTSAYEFLELRYGPSIRVYGAIAFLVAQLVRLAMILWLLSLLIQQVTDLTPTTAIILGGF
FVGFYTVIGGIDAVIWTDVLQTVILLLGGLVCLWVILEALPGGLNQVFEQAGQAGKFALAPWENGAPAETSWSFSLSEKT
ATMMLLIGLTNWLTEYSSNQNTVQRYCASQSTKEARRGLWVYLFTALPIWAFYMLLGTALWVFFQVYPDAQASAILTGET
RAETLMPHFITGYLPAGVAGLVIAAALAAAMSSLDSSINSITTVSVVDLYRRHLRPGRDDRHYLKVAWAIAAAVTGVMIL
GALWLNQADTKTLQDTSTILVSLLGGGMLGLYLLGFFSKKGNARAAWVGIGCTLVFTSWTILTNNQLLPEALSAPFDLYY
TGLIGNVLMFLVGYVVALLWPAASVAPVSPQPAAEG

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI167466278, Length=467, Percent_Identity=26.338329764454, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI256985183, Length=468, Percent_Identity=28.2051282051282, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI157671931, Length=481, Percent_Identity=26.1954261954262, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI4507035, Length=480, Percent_Identity=28.9583333333333, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI109659836, Length=486, Percent_Identity=27.3662551440329, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI109659839, Length=496, Percent_Identity=27.4193548387097, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI17941285, Length=473, Percent_Identity=27.061310782241, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4507033, Length=411, Percent_Identity=25.7907542579075, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI206597483, Length=453, Percent_Identity=25.3863134657837, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI110835708, Length=500, Percent_Identity=23.6, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507031, Length=464, Percent_Identity=23.2758620689655, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI14140236, Length=474, Percent_Identity=22.1518987341772, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87082237, Length=377, Percent_Identity=25.1989389920424, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790113, Length=485, Percent_Identity=23.7113402061856, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790503, Length=413, Percent_Identity=24.455205811138, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566512, Length=385, Percent_Identity=25.7142857142857, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533094, Length=471, Percent_Identity=24.8407643312102, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651741, Length=492, Percent_Identity=28.6585365853659, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24651739, Length=478, Percent_Identity=28.6610878661088, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24640370, Length=497, Percent_Identity=27.364185110664, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24645928, Length=379, Percent_Identity=28.4960422163588, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573698, Length=472, Percent_Identity=25.635593220339, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI221459586, Length=494, Percent_Identity=25.9109311740891, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281362918, Length=498, Percent_Identity=26.5060240963855, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI221459588, Length=489, Percent_Identity=24.5398773006135, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221459584, Length=493, Percent_Identity=24.3407707910751, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24650192, Length=467, Percent_Identity=27.6231263383298, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641117, Length=479, Percent_Identity=26.7223382045929, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28574994, Length=463, Percent_Identity=25.2699784017279, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920916, Length=480, Percent_Identity=23.9583333333333, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221459582, Length=498, Percent_Identity=25.9036144578313, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI221379702, Length=402, Percent_Identity=26.3681592039801, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281364280, Length=435, Percent_Identity=24.1379310344828, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI161076631, Length=495, Percent_Identity=23.4343434343434, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281362054, Length=446, Percent_Identity=22.4215246636771, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281362052, Length=446, Percent_Identity=22.4215246636771, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281362050, Length=446, Percent_Identity=22.4215246636771, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648056, Length=446, Percent_Identity=22.4215246636771, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356827, Length=446, Percent_Identity=22.4215246636771, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56398; Mature: 56266

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAIADWIVLAGYLCIVLGIGIYFSRRNTNTEEYFVGGRRFRGWVIGLSLVGTSISSIT
CCEEHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHHEEHHHHHHCCHHHHE
FLAYPADAFLTDWLRYLPNLALLPAMLVAAFVFLPFFRRENMTSAYEFLELRYGPSIRVY
EEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
GAIAFLVAQLVRLAMILWLLSLLIQQVTDLTPTTAIILGGFFVGFYTVIGGIDAVIWTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVILLLGGLVCLWVILEALPGGLNQVFEQAGQAGKFALAPWENGAPAETSWSFSLSEK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECHH
TATMMLLIGLTNWLTEYSSNQNTVQRYCASQSTKEARRGLWVYLFTALPIWAFYMLLGTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LWVFFQVYPDAQASAILTGETRAETLMPHFITGYLPAGVAGLVIAAALAAAMSSLDSSIN
HHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITTVSVVDLYRRHLRPGRDDRHYLKVAWAIAAAVTGVMILGALWLNQADTKTLQDTSTI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LVSLLGGGMLGLYLLGFFSKKGNARAAWVGIGCTLVFTSWTILTNNQLLPEALSAPFDLY
HHHHHCCHHHHHHHHHHHCCCCCCEEEEEEHHHEEHHHHEEEEECCCCCHHHHCCCHHHH
YTGLIGNVLMFLVGYVVALLWPAASVAPVSPQPAAEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLAIADWIVLAGYLCIVLGIGIYFSRRNTNTEEYFVGGRRFRGWVIGLSLVGTSISSIT
CEEHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHHEEHHHHHHCCHHHHE
FLAYPADAFLTDWLRYLPNLALLPAMLVAAFVFLPFFRRENMTSAYEFLELRYGPSIRVY
EEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
GAIAFLVAQLVRLAMILWLLSLLIQQVTDLTPTTAIILGGFFVGFYTVIGGIDAVIWTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVILLLGGLVCLWVILEALPGGLNQVFEQAGQAGKFALAPWENGAPAETSWSFSLSEK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECHH
TATMMLLIGLTNWLTEYSSNQNTVQRYCASQSTKEARRGLWVYLFTALPIWAFYMLLGTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LWVFFQVYPDAQASAILTGETRAETLMPHFITGYLPAGVAGLVIAAALAAAMSSLDSSIN
HHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITTVSVVDLYRRHLRPGRDDRHYLKVAWAIAAAVTGVMILGALWLNQADTKTLQDTSTI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LVSLLGGGMLGLYLLGFFSKKGNARAAWVGIGCTLVFTSWTILTNNQLLPEALSAPFDLY
HHHHHCCHHHHHHHHHHHCCCCCCEEEEEEHHHEEHHHHEEEEECCCCCHHHHCCCHHHH
YTGLIGNVLMFLVGYVVALLWPAASVAPVSPQPAAEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]