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The map label for this gene is gph [H]

Identifier: 110834615

GI number: 110834615

Start: 2000333

End: 2001001

Strand: Direct

Name: gph [H]

Synonym: ABO_1754

Alternate gene names: 110834615

Gene position: 2000333-2001001 (Clockwise)

Preceding gene: 110834614

Following gene: 110834616

Centisome position: 64.11

GC content: 56.95

Gene sequence:

>669_bases
ATGGAACGCCTTGAAGCCGTTTATTTCGATTTGGATGGCACCCTTATCGATACCGCCCCGGACTTTTATACGGTACTCAA
TACATTGCTGGAAAAGCATAGTCGCCCCACAGTGAGCTACTCTGCGGTGCGCGCTAATGTATCCAATGGCGCGCGCGCGC
TCACCGAACTCGGTTTTGGTGTTGGCCCCGACGATGCAAGCTTTGCTCTGTTGCTGAACGAACTGCTCAATGCCTACGAA
CAGCATCTGGCCGTGGATACGGTATTGTTCCCAGGCTTGGAGGACGTGCTCGACTGGCTGGACGCTCAGCAACTGCCCTG
GGGTATCGTCACCAACAAACCCGACCGCTTTACCGGCCCCGTACTGGAAGGGCTCAAGCTGCACCAACGCGTTGGCCCGG
TGATTTGCCCGGAGCACGTCAAGCAACGCAAACCCGACCCGGAAGGCCTATTGATTGCCGCCAACGCCGACCAGGTAAAA
CCCGCACATTGCCTGTATGTGGGCGATCACCTGCGCGACATTCAAGCTGGCAAGAATGCGGGCATGGCCACCGCCGTTGC
CGCCTTTGGTTACATCGATGCAGACGACGACCCTCGTGGCTGGCAGGCAGATTATTACCTGGAAGACGGCAGCGACCTGC
TGCCGCTTTTGCAGAAACTCTATACATAA

Upstream 100 bases:

>100_bases
TATAACCCGCTCACCCAGGTTTACAAACTGAATCGGGATGTATCGGTGAATTACTTGATGCACGCCCGCAAGGGCGACTG
ATTGCCTGCGGGAGCCAATA

Downstream 100 bases:

>100_bases
AACGCGGACTAAACTAATCATAGGGCAGCACTAGAACGGCAATTAAGGCAGATGCCCGCTCCACCTTACGGTTAGTTACA
GCACCTAAGTCAGGCCTCGT

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 2; PGPase2 [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MERLEAVYFDLDGTLIDTAPDFYTVLNTLLEKHSRPTVSYSAVRANVSNGARALTELGFGVGPDDASFALLLNELLNAYE
QHLAVDTVLFPGLEDVLDWLDAQQLPWGIVTNKPDRFTGPVLEGLKLHQRVGPVICPEHVKQRKPDPEGLLIAANADQVK
PAHCLYVGDHLRDIQAGKNAGMATAVAAFGYIDADDDPRGWQADYYLEDGSDLLPLLQKLYT

Sequences:

>Translated_222_residues
MERLEAVYFDLDGTLIDTAPDFYTVLNTLLEKHSRPTVSYSAVRANVSNGARALTELGFGVGPDDASFALLLNELLNAYE
QHLAVDTVLFPGLEDVLDWLDAQQLPWGIVTNKPDRFTGPVLEGLKLHQRVGPVICPEHVKQRKPDPEGLLIAANADQVK
PAHCLYVGDHLRDIQAGKNAGMATAVAAFGYIDADDDPRGWQADYYLEDGSDLLPLLQKLYT
>Mature_222_residues
MERLEAVYFDLDGTLIDTAPDFYTVLNTLLEKHSRPTVSYSAVRANVSNGARALTELGFGVGPDDASFALLLNELLNAYE
QHLAVDTVLFPGLEDVLDWLDAQQLPWGIVTNKPDRFTGPVLEGLKLHQRVGPVICPEHVKQRKPDPEGLLIAANADQVK
PAHCLYVGDHLRDIQAGKNAGMATAVAAFGYIDADDDPRGWQADYYLEDGSDLLPLLQKLYT

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=242, Percent_Identity=33.0578512396694, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24401; Mature: 24401

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLEAVYFDLDGTLIDTAPDFYTVLNTLLEKHSRPTVSYSAVRANVSNGARALTELGFG
CCCCEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCCEEHHHHHHCCCHHHHHHHHHCCC
VGPDDASFALLLNELLNAYEQHLAVDTVLFPGLEDVLDWLDAQQLPWGIVTNKPDRFTGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VLEGLKLHQRVGPVICPEHVKQRKPDPEGLLIAANADQVKPAHCLYVGDHLRDIQAGKNA
HHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCC
GMATAVAAFGYIDADDDPRGWQADYYLEDGSDLLPLLQKLYT
CHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MERLEAVYFDLDGTLIDTAPDFYTVLNTLLEKHSRPTVSYSAVRANVSNGARALTELGFG
CCCCEEEEEECCCEEECCCCHHHHHHHHHHHHCCCCCEEHHHHHHCCCHHHHHHHHHCCC
VGPDDASFALLLNELLNAYEQHLAVDTVLFPGLEDVLDWLDAQQLPWGIVTNKPDRFTGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VLEGLKLHQRVGPVICPEHVKQRKPDPEGLLIAANADQVKPAHCLYVGDHLRDIQAGKNA
HHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCC
GMATAVAAFGYIDADDDPRGWQADYYLEDGSDLLPLLQKLYT
CHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]