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The map label for this gene is acdA [H]

Identifier: 110834562

GI number: 110834562

Start: 1936837

End: 1938144

Strand: Direct

Name: acdA [H]

Synonym: ABO_1701

Alternate gene names: 110834562

Gene position: 1936837-1938144 (Clockwise)

Preceding gene: 110834561

Following gene: 110834563

Centisome position: 62.08

GC content: 58.72

Gene sequence:

>1308_bases
ATGGCGAGAAATGCAGTGGGGTATGCGCTAACCGCGCTTAACCGCCTGGCCTGCTCGGAAGTACTCGACAAGATCGGCAT
GCGCAAAAGTGTCGAACGGCTTGCCTACACCCTCACCAAAAGCGGGTTCCAGGTACTCACCACCACCGCCCGTGCGTTCA
AATCGGCTAGCTCAGGCAACAAGCCCCAGCGCCTGGCCGCGCCCGGCCATACCCGCGATCTGTTCGACCTTGGCATTACC
GACGAACAACAGATGATCCGCGACAGCGTTCAAGGCTTTGCCATGGACGTGCTGCGTGAGCAGGCCGAACACGCCGACGC
CGCACAGCAGACTAGTGATGAGGTTATTGGTCAGGCTCAAGAGTTGGGCCTTAACTTCTTCGCGGTACCGGAAGCGCTCG
GGGGTGCAGCCACCGAGAGATCCACCGTTACCAGCATGCTGCTGGCAGAAGACCTGGCCCACGGCGACATGGGCCAAGCG
GTAGCGATTCTTGCTCCCATGGGCGTGGCCAATGCCCTGACCCAGTGGGGCACCGCGCAGCAACAAGACAAATATCTAAG
CAGCTTCGCGGAAGAAAATCCGCCCAAAGCTACCATTGCTGTATGCGAGCCGCGTCCCTTGTTCGACCCAATGGTGCTGG
CCACCACCGCACGCAAAGATGGCAACGATTACATTCTTAACGGGGAGAAATCTCTGGTGCCATTGGCGGCCGAAGCAGAA
ATCTTCCTGATAGCGGCACAAACCGATAGCGGCCCGGCTGTGTTCATTGTGGAAGGTGGCAACGACGGGCTCACTGCCGG
TAACGATCCCTCCATGGGCATCCGCGCCAGCAGCCAACGCCCACTGAAACTGGACGAGGTCCGCATCCCAGCAGACAACC
GTTTGGGCAATGACGATTTTGATTATCGCGCTTTTGTAGATCTGGGCACTCTAGCCTGGTGTGCCATGACCATTGGCACG
AGCCAGGCGGTACTCGATTACGTTGGCCCCTACTGCAACGAACGCACCGCCTTTGGCGAACCCATCAGCCACCGTCAATC
TGTGGCATTCATGATCGCCGATATGGCCATCGAATTAGATGCCATGCGCATGCTCACCTACCGCGCCGCCAGCCGTGCCG
AACAGGGCAAAAGCTTCCAGCGAGAAACCCACCTGGCGCGTACCTTAGTCAAAGATAAAGCCATGAAAATCGGTACCGAC
GGCGTGCAACTGCTCGGTGGCCACGGCTTCACTAAAGAGTACCCGGTGGAACGCTGGTATCGGGATCTGCGTGCTGTGGG
TATCGCCTTCGGCGGCCTGCACCTGTAA

Upstream 100 bases:

>100_bases
TGCCACTATGCCCGGCCAGCCAGTCACACTGGTCAATGTGGCTCTGCCCCATCTCGCCATAATCGAGTGCAATCCATAGA
CACAACAATGAGGTTTCACC

Downstream 100 bases:

>100_bases
GGAGGGAGACAACCATGAATATTGAAATTCCCAAGAAGTTTAAACCCCTAATTAACAACGCCTATCAGGTAGCCCAAAGC
ACTCTCCGTCCGCTGTCGCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MARNAVGYALTALNRLACSEVLDKIGMRKSVERLAYTLTKSGFQVLTTTARAFKSASSGNKPQRLAAPGHTRDLFDLGIT
DEQQMIRDSVQGFAMDVLREQAEHADAAQQTSDEVIGQAQELGLNFFAVPEALGGAATERSTVTSMLLAEDLAHGDMGQA
VAILAPMGVANALTQWGTAQQQDKYLSSFAEENPPKATIAVCEPRPLFDPMVLATTARKDGNDYILNGEKSLVPLAAEAE
IFLIAAQTDSGPAVFIVEGGNDGLTAGNDPSMGIRASSQRPLKLDEVRIPADNRLGNDDFDYRAFVDLGTLAWCAMTIGT
SQAVLDYVGPYCNERTAFGEPISHRQSVAFMIADMAIELDAMRMLTYRAASRAEQGKSFQRETHLARTLVKDKAMKIGTD
GVQLLGGHGFTKEYPVERWYRDLRAVGIAFGGLHL

Sequences:

>Translated_435_residues
MARNAVGYALTALNRLACSEVLDKIGMRKSVERLAYTLTKSGFQVLTTTARAFKSASSGNKPQRLAAPGHTRDLFDLGIT
DEQQMIRDSVQGFAMDVLREQAEHADAAQQTSDEVIGQAQELGLNFFAVPEALGGAATERSTVTSMLLAEDLAHGDMGQA
VAILAPMGVANALTQWGTAQQQDKYLSSFAEENPPKATIAVCEPRPLFDPMVLATTARKDGNDYILNGEKSLVPLAAEAE
IFLIAAQTDSGPAVFIVEGGNDGLTAGNDPSMGIRASSQRPLKLDEVRIPADNRLGNDDFDYRAFVDLGTLAWCAMTIGT
SQAVLDYVGPYCNERTAFGEPISHRQSVAFMIADMAIELDAMRMLTYRAASRAEQGKSFQRETHLARTLVKDKAMKIGTD
GVQLLGGHGFTKEYPVERWYRDLRAVGIAFGGLHL
>Mature_434_residues
ARNAVGYALTALNRLACSEVLDKIGMRKSVERLAYTLTKSGFQVLTTTARAFKSASSGNKPQRLAAPGHTRDLFDLGITD
EQQMIRDSVQGFAMDVLREQAEHADAAQQTSDEVIGQAQELGLNFFAVPEALGGAATERSTVTSMLLAEDLAHGDMGQAV
AILAPMGVANALTQWGTAQQQDKYLSSFAEENPPKATIAVCEPRPLFDPMVLATTARKDGNDYILNGEKSLVPLAAEAEI
FLIAAQTDSGPAVFIVEGGNDGLTAGNDPSMGIRASSQRPLKLDEVRIPADNRLGNDDFDYRAFVDLGTLAWCAMTIGTS
QAVLDYVGPYCNERTAFGEPISHRQSVAFMIADMAIELDAMRMLTYRAASRAEQGKSFQRETHLARTLVKDKAMKIGTDG
VQLLGGHGFTKEYPVERWYRDLRAVGIAFGGLHL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=412, Percent_Identity=30.5825242718447, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI4501859, Length=364, Percent_Identity=31.3186813186813, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI4557231, Length=407, Percent_Identity=30.7125307125307, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI4557233, Length=367, Percent_Identity=30.2452316076294, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=28.1842818428184, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=28.486646884273, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI7656849, Length=364, Percent_Identity=25.2747252747253, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4501857, Length=397, Percent_Identity=25.1889168765743, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=27.893175074184, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4557235, Length=337, Percent_Identity=27.893175074184, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503943, Length=411, Percent_Identity=25.3041362530414, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI7669494, Length=403, Percent_Identity=25.3101736972705, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI21361497, Length=342, Percent_Identity=25.7309941520468, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87081958, Length=368, Percent_Identity=26.0869565217391, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786223, Length=371, Percent_Identity=23.4501347708895, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=34.1207349081365, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=32.5966850828729, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=31.043956043956, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=368, Percent_Identity=30.4347826086957, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=358, Percent_Identity=31.0055865921788, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=324, Percent_Identity=29.9382716049383, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=25.9459459459459, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=373, Percent_Identity=27.6139410187668, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=359, Percent_Identity=21.7270194986072, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=29.9145299145299, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=225, Percent_Identity=27.5555555555556, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=25.0909090909091, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=340, Percent_Identity=26.1764705882353, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=23.1382978723404, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=322, Percent_Identity=25.776397515528, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=332, Percent_Identity=25, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=31.5068493150685, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=31.1653116531165, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=29.4277929155313, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646207, Length=402, Percent_Identity=29.6019900497512, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21355753, Length=367, Percent_Identity=24.7956403269755, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281363737, Length=368, Percent_Identity=26.3586956521739, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19920834, Length=415, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 47029; Mature: 46898

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNAVGYALTALNRLACSEVLDKIGMRKSVERLAYTLTKSGFQVLTTTARAFKSASSGN
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
KPQRLAAPGHTRDLFDLGITDEQQMIRDSVQGFAMDVLREQAEHADAAQQTSDEVIGQAQ
CCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGLNFFAVPEALGGAATERSTVTSMLLAEDLAHGDMGQAVAILAPMGVANALTQWGTAQ
HCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCHH
QQDKYLSSFAEENPPKATIAVCEPRPLFDPMVLATTARKDGNDYILNGEKSLVPLAAEAE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHEEEECCCCCCCEEECCCCCEEEEECCCE
IFLIAAQTDSGPAVFIVEGGNDGLTAGNDPSMGIRASSQRPLKLDEVRIPADNRLGNDDF
EEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCEECEEECCCCCCCCCCCC
DYRAFVDLGTLAWCAMTIGTSQAVLDYVGPYCNERTAFGEPISHRQSVAFMIADMAIELD
CEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMRMLTYRAASRAEQGKSFQRETHLARTLVKDKAMKIGTDGVQLLGGHGFTKEYPVERWY
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCHHHHH
RDLRAVGIAFGGLHL
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARNAVGYALTALNRLACSEVLDKIGMRKSVERLAYTLTKSGFQVLTTTARAFKSASSGN
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
KPQRLAAPGHTRDLFDLGITDEQQMIRDSVQGFAMDVLREQAEHADAAQQTSDEVIGQAQ
CCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGLNFFAVPEALGGAATERSTVTSMLLAEDLAHGDMGQAVAILAPMGVANALTQWGTAQ
HCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCHH
QQDKYLSSFAEENPPKATIAVCEPRPLFDPMVLATTARKDGNDYILNGEKSLVPLAAEAE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHEEEECCCCCCCEEECCCCCEEEEECCCE
IFLIAAQTDSGPAVFIVEGGNDGLTAGNDPSMGIRASSQRPLKLDEVRIPADNRLGNDDF
EEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCEECEEECCCCCCCCCCCC
DYRAFVDLGTLAWCAMTIGTSQAVLDYVGPYCNERTAFGEPISHRQSVAFMIADMAIELD
CEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMRMLTYRAASRAEQGKSFQRETHLARTLVKDKAMKIGTDGVQLLGGHGFTKEYPVERWY
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCHHHHH
RDLRAVGIAFGGLHL
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]