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The map label for this gene is bcd [H]

Identifier: 110834563

GI number: 110834563

Start: 1938159

End: 1939364

Strand: Direct

Name: bcd [H]

Synonym: ABO_1702

Alternate gene names: 110834563

Gene position: 1938159-1939364 (Clockwise)

Preceding gene: 110834562

Following gene: 110834565

Centisome position: 62.12

GC content: 54.73

Gene sequence:

>1206_bases
ATGAATATTGAAATTCCCAAGAAGTTTAAACCCCTAATTAACAACGCCTATCAGGTAGCCCAAAGCACTCTCCGTCCGCT
GTCGCGCAAGTATGACCGCGGTGAGCACGAATATCCGAAAGAATTGGATATGCTCGCCTCGGTATTGGATGGCTTTAACG
AAGGCGACCCGGCCAATTCCGCTGGCGCCGCCACCACCGGTAGCGGCAAGGTGCAGGATGACGGCAGCGTCAAAAATGGC
GCTAACATGGGCGTATGCTTGGGTGCCATGGAAATGTGCTACGGCGATACCGGCTTCCTGTTGGCCATGCCCCGCCAGGG
TCTAGGTAACGCGGCCATCGCGGCCGTAGCCAACGACGAACAACTGGAACGCTTTAAAGGCAAATGGGCCGCCATGGCCA
TCACCGAGCCCGGCTGCGGCTCCGACTCCGCAGCCATTCGCACCACCGCTAAACAGGACGGCGACCACTACATTCTCAAT
GGTGAGAAAATTTTTGTGACCTCCGGAGAGCGCGCCGACTGCGTGGTGGTATGGGCCTCACTGGACCCAAAGCTGGGCCG
CGCGGCCATCAAGTCTTTCGTCGTAGACTGGGGCACCCCGGGCATGGAACTGGCACGCCTTGAGAAGAAGCTCGGCATCC
GTGCTTCCGACACCGCAGCGATTAATTTTGTGGACTGCCGGGTACCGGCAGAAAATCTGCTCGGCACCCCGGAGATCGAC
ACCAAGAAAGGCTTTGCGGGTGTCATGGAGACCTTCGACAATACACGCCCGCTGGTGGCGGCCATGGCCATTGGTTGTGC
CAAGGCCTCCCTAGAGCGCATCAAGGAGTTGCTCAAAGACAGCATCAACTACGATTACAGTAAACCGGTAGACAACTGCT
CCGCAGTAGAAGCGGAAATTTACAAGATGGAAGCTGACTGGGAAGCGGCCTATTGGCTTGCTGTGAAGGCGGCATGGATG
GCCGACAATAAGAAAGCCAACACCTTGGAGGCCTCCATTTCAAAAGCCAAGGCCGGGCGTGTTGGTAATGCCATTACTTT
ACGCTGTGTGGAATTAGCAGGCAGTTTGGGTTACACCGAAGATGAATTGCTAGAAAAGTGGGCCCGTGATTCAAAAATCC
TAGATATCTTTGAAGGCACCCAACAAATTCAACAACTCGTTATCGCTCGCCGTATATTGGGGCTTAGTTCCAAAGAATTG
AAGTAA

Upstream 100 bases:

>100_bases
ACGGCTTCACTAAAGAGTACCCGGTGGAACGCTGGTATCGGGATCTGCGTGCTGTGGGTATCGCCTTCGGCGGCCTGCAC
CTGTAAGGAGGGAGACAACC

Downstream 100 bases:

>100_bases
CATTGCCCGAGCAATACCTTCTGATAAAAAGCCGTTTCTGATATTAGTCAGAAGCGGCTTTTTTGATTAACCGAATATAG
AAGGCATAACCTTGCTGCAC

Product: acyl-CoA dehydrogenase middle domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNIEIPKKFKPLINNAYQVAQSTLRPLSRKYDRGEHEYPKELDMLASVLDGFNEGDPANSAGAATTGSGKVQDDGSVKNG
ANMGVCLGAMEMCYGDTGFLLAMPRQGLGNAAIAAVANDEQLERFKGKWAAMAITEPGCGSDSAAIRTTAKQDGDHYILN
GEKIFVTSGERADCVVVWASLDPKLGRAAIKSFVVDWGTPGMELARLEKKLGIRASDTAAINFVDCRVPAENLLGTPEID
TKKGFAGVMETFDNTRPLVAAMAIGCAKASLERIKELLKDSINYDYSKPVDNCSAVEAEIYKMEADWEAAYWLAVKAAWM
ADNKKANTLEASISKAKAGRVGNAITLRCVELAGSLGYTEDELLEKWARDSKILDIFEGTQQIQQLVIARRILGLSSKEL
K

Sequences:

>Translated_401_residues
MNIEIPKKFKPLINNAYQVAQSTLRPLSRKYDRGEHEYPKELDMLASVLDGFNEGDPANSAGAATTGSGKVQDDGSVKNG
ANMGVCLGAMEMCYGDTGFLLAMPRQGLGNAAIAAVANDEQLERFKGKWAAMAITEPGCGSDSAAIRTTAKQDGDHYILN
GEKIFVTSGERADCVVVWASLDPKLGRAAIKSFVVDWGTPGMELARLEKKLGIRASDTAAINFVDCRVPAENLLGTPEID
TKKGFAGVMETFDNTRPLVAAMAIGCAKASLERIKELLKDSINYDYSKPVDNCSAVEAEIYKMEADWEAAYWLAVKAAWM
ADNKKANTLEASISKAKAGRVGNAITLRCVELAGSLGYTEDELLEKWARDSKILDIFEGTQQIQQLVIARRILGLSSKEL
K
>Mature_401_residues
MNIEIPKKFKPLINNAYQVAQSTLRPLSRKYDRGEHEYPKELDMLASVLDGFNEGDPANSAGAATTGSGKVQDDGSVKNG
ANMGVCLGAMEMCYGDTGFLLAMPRQGLGNAAIAAVANDEQLERFKGKWAAMAITEPGCGSDSAAIRTTAKQDGDHYILN
GEKIFVTSGERADCVVVWASLDPKLGRAAIKSFVVDWGTPGMELARLEKKLGIRASDTAAINFVDCRVPAENLLGTPEID
TKKGFAGVMETFDNTRPLVAAMAIGCAKASLERIKELLKDSINYDYSKPVDNCSAVEAEIYKMEADWEAAYWLAVKAAWM
ADNKKANTLEASISKAKAGRVGNAITLRCVELAGSLGYTEDELLEKWARDSKILDIFEGTQQIQQLVIARRILGLSSKEL
K

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=400, Percent_Identity=33.75, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4557231, Length=400, Percent_Identity=33.75, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4557233, Length=401, Percent_Identity=30.1745635910224, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI4501859, Length=265, Percent_Identity=33.9622641509434, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI7656849, Length=288, Percent_Identity=29.8611111111111, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI4501857, Length=297, Percent_Identity=29.96632996633, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI76496475, Length=299, Percent_Identity=30.1003344481605, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4557235, Length=299, Percent_Identity=30.1003344481605, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226958412, Length=281, Percent_Identity=27.4021352313167, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI226958414, Length=281, Percent_Identity=27.4021352313167, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI21361497, Length=318, Percent_Identity=28.3018867924528, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI4503943, Length=332, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7669494, Length=316, Percent_Identity=23.4177215189873, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI211971008, Length=331, Percent_Identity=22.9607250755287, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI48976061, Length=331, Percent_Identity=22.9607250755287, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786223, Length=280, Percent_Identity=25.3571428571429, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081958, Length=265, Percent_Identity=27.1698113207547, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=411, Percent_Identity=32.8467153284672, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17570075, Length=317, Percent_Identity=36.2776025236593, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17534899, Length=402, Percent_Identity=31.3432835820896, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17508101, Length=285, Percent_Identity=31.2280701754386, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17506239, Length=263, Percent_Identity=31.5589353612167, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=311, Percent_Identity=29.2604501607717, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71990804, Length=228, Percent_Identity=28.5087719298246, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=28.7449392712551, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=269, Percent_Identity=26.7657992565056, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=269, Percent_Identity=24.907063197026, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=302, Percent_Identity=27.4834437086093, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=259, Percent_Identity=29.3436293436293, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=309, Percent_Identity=26.2135922330097, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=150, Percent_Identity=34, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=285, Percent_Identity=27.3684210526316, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=330, Percent_Identity=23.9393939393939, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=34.3669250645995, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356377, Length=262, Percent_Identity=36.6412213740458, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24666513, Length=291, Percent_Identity=32.6460481099656, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24646207, Length=319, Percent_Identity=30.0940438871473, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281363737, Length=311, Percent_Identity=32.1543408360129, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19920834, Length=336, Percent_Identity=28.8690476190476, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355753, Length=280, Percent_Identity=27.1428571428571, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43405; Mature: 43405

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEIPKKFKPLINNAYQVAQSTLRPLSRKYDRGEHEYPKELDMLASVLDGFNEGDPANS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
AGAATTGSGKVQDDGSVKNGANMGVCLGAMEMCYGDTGFLLAMPRQGLGNAAIAAVANDE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCHH
QLERFKGKWAAMAITEPGCGSDSAAIRTTAKQDGDHYILNGEKIFVTSGERADCVVVWAS
HHHHHCCCEEEEEEECCCCCCCCCCEEEHHCCCCCEEEECCCEEEEECCCCCCEEEEEEC
LDPKLGRAAIKSFVVDWGTPGMELARLEKKLGIRASDTAAINFVDCRVPAENLLGTPEID
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCC
TKKGFAGVMETFDNTRPLVAAMAIGCAKASLERIKELLKDSINYDYSKPVDNCSAVEAEI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEE
YKMEADWEAAYWLAVKAAWMADNKKANTLEASISKAKAGRVGNAITLRCVELAGSLGYTE
EEECCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
DELLEKWARDSKILDIFEGTQQIQQLVIARRILGLSSKELK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIEIPKKFKPLINNAYQVAQSTLRPLSRKYDRGEHEYPKELDMLASVLDGFNEGDPANS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
AGAATTGSGKVQDDGSVKNGANMGVCLGAMEMCYGDTGFLLAMPRQGLGNAAIAAVANDE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCHH
QLERFKGKWAAMAITEPGCGSDSAAIRTTAKQDGDHYILNGEKIFVTSGERADCVVVWAS
HHHHHCCCEEEEEEECCCCCCCCCCEEEHHCCCCCEEEECCCEEEEECCCCCCEEEEEEC
LDPKLGRAAIKSFVVDWGTPGMELARLEKKLGIRASDTAAINFVDCRVPAENLLGTPEID
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCC
TKKGFAGVMETFDNTRPLVAAMAIGCAKASLERIKELLKDSINYDYSKPVDNCSAVEAEI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEE
YKMEADWEAAYWLAVKAAWMADNKKANTLEASISKAKAGRVGNAITLRCVELAGSLGYTE
EEECCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
DELLEKWARDSKILDIFEGTQQIQQLVIARRILGLSSKELK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]