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The map label for this gene is pabB [H]

Identifier: 110834296

GI number: 110834296

Start: 1639292

End: 1640428

Strand: Direct

Name: pabB [H]

Synonym: ABO_1435

Alternate gene names: 110834296

Gene position: 1639292-1640428 (Clockwise)

Preceding gene: 110834289

Following gene: 110834300

Centisome position: 52.54

GC content: 54.0

Gene sequence:

>1137_bases
ATGACTTACCCTTGCGTTTTTCAATCTGAAGGTAGCTTACGCTGGCTCGGTGAGCCGGATGCGGTATTGAGCGCCCAGTC
ATTGTCACAATTGCATGAGCTACGAGCCAACATAGAATACGCGCTAGCAAACGAATACTGTTTCGTTGCAGGCATACTGC
CCTATGAAGTAGGGTCCGCATTACACGGATTACCTTGCGCCCCCTTTACTGCCTGGGCATACCTGTATAAAGACGCTCCC
AGCCAGAACACACCTAACGCCGCTCTCGTCAGCACACCGACCGGCGCAGAAAACTTTGCCCTGGAGTCGGCATTTAAGCC
GGAACAAACGCAACAAGCCTATTTGGCCAGCCTGTCACGGATCCAAGCCTATCTGCGCGCTGGCGACTGCTACCAGGTCA
ACTTAGCCCAGCGTTTTTCTACCCATTTCAGCGGCTCCACTCTCAGCGCTTGGCTTGGCTTACAACAGGCCCACCCCGCC
CCACATAGCTGCTATTTCCAAACGGATGACGGCAACAGTGTATTCGGGGTTTCACCGGAGCGTTTTCTTTCCATCAGGAA
TCGACAGGTAGTGGCGGAGCCTATCAAGGGCTCTCGCCCGCGAGGCGCTAACCCTGAAGAAGATGGTCGGCTGGCGGCTG
AGTTAAGAGCCAACCCCAAAGACCTGGCCGAGAATCTGATGATAGTGGATCTGCTACGCAATGATCTGGGGCTCAGCTGT
GAATCGGGCAGCATCCAGGCTTCGCCACTATTTGAATTACGCCAGTTCAGCAATGTACAACACCTTGTCAGCACCATCAC
CGGCACCCTGAAAGCCGACATCACGCCGCTGGAGGCTCTATTCCGTGCCTTTCCTGGGGGGTCGATTACCGGGGCTCCCA
AGCAACGAGCCATGGAAATCATCACCGAACTTGAGCCTGTCGCCCGTGGAGCCTATTGCGGTAGTTTCTTCTGGATGGAC
GATCAAGAGAACCTGGACAGCAACATCCTGATTCGCACTATGCAAACTGACGGAGATCGGATCTACTGCCATGGCGGCGG
CGGAATCGTATTTGATTCAGACCCCTTAGCAGAATACGAGGAAAGTCTGTTCAAGGTGGAAAAGCTGATGCGGGCTCTTG
AGGAAAGATTTCTTTAA

Upstream 100 bases:

>100_bases
CGGCCTGTGTTCTGCGGTATAACCGTTACTCATCAGCAACAAGAATGGGCATCGTTGCATTACGCGGGTAGACTAGCGCC
TCATTTTACTCTGGCAGCTC

Downstream 100 bases:

>100_bases
GTGCCACTTCGTGCAGCGCGTGCTACGCAACACGCCAAATTTATTGGCCTGTTGCGTACAGCCTGCCACAACGTTACAGC
GAAATATCGCGTTCGCTGGC

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTYPCVFQSEGSLRWLGEPDAVLSAQSLSQLHELRANIEYALANEYCFVAGILPYEVGSALHGLPCAPFTAWAYLYKDAP
SQNTPNAALVSTPTGAENFALESAFKPEQTQQAYLASLSRIQAYLRAGDCYQVNLAQRFSTHFSGSTLSAWLGLQQAHPA
PHSCYFQTDDGNSVFGVSPERFLSIRNRQVVAEPIKGSRPRGANPEEDGRLAAELRANPKDLAENLMIVDLLRNDLGLSC
ESGSIQASPLFELRQFSNVQHLVSTITGTLKADITPLEALFRAFPGGSITGAPKQRAMEIITELEPVARGAYCGSFFWMD
DQENLDSNILIRTMQTDGDRIYCHGGGGIVFDSDPLAEYEESLFKVEKLMRALEERFL

Sequences:

>Translated_378_residues
MTYPCVFQSEGSLRWLGEPDAVLSAQSLSQLHELRANIEYALANEYCFVAGILPYEVGSALHGLPCAPFTAWAYLYKDAP
SQNTPNAALVSTPTGAENFALESAFKPEQTQQAYLASLSRIQAYLRAGDCYQVNLAQRFSTHFSGSTLSAWLGLQQAHPA
PHSCYFQTDDGNSVFGVSPERFLSIRNRQVVAEPIKGSRPRGANPEEDGRLAAELRANPKDLAENLMIVDLLRNDLGLSC
ESGSIQASPLFELRQFSNVQHLVSTITGTLKADITPLEALFRAFPGGSITGAPKQRAMEIITELEPVARGAYCGSFFWMD
DQENLDSNILIRTMQTDGDRIYCHGGGGIVFDSDPLAEYEESLFKVEKLMRALEERFL
>Mature_377_residues
TYPCVFQSEGSLRWLGEPDAVLSAQSLSQLHELRANIEYALANEYCFVAGILPYEVGSALHGLPCAPFTAWAYLYKDAPS
QNTPNAALVSTPTGAENFALESAFKPEQTQQAYLASLSRIQAYLRAGDCYQVNLAQRFSTHFSGSTLSAWLGLQQAHPAP
HSCYFQTDDGNSVFGVSPERFLSIRNRQVVAEPIKGSRPRGANPEEDGRLAAELRANPKDLAENLMIVDLLRNDLGLSCE
SGSIQASPLFELRQFSNVQHLVSTITGTLKADITPLEALFRAFPGGSITGAPKQRAMEIITELEPVARGAYCGSFFWMDD
QENLDSNILIRTMQTDGDRIYCHGGGGIVFDSDPLAEYEESLFKVEKLMRALEERFL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=279, Percent_Identity=46.2365591397849, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1787518, Length=273, Percent_Identity=34.7985347985348, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87082077, Length=198, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786809, Length=213, Percent_Identity=24.8826291079812, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=300, Percent_Identity=34.6666666666667, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324361, Length=284, Percent_Identity=26.7605633802817, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 41605; Mature: 41474

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01109 RIBOSOMAL_L10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPCVFQSEGSLRWLGEPDAVLSAQSLSQLHELRANIEYALANEYCFVAGILPYEVGSA
CCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCHHHHHHH
LHGLPCAPFTAWAYLYKDAPSQNTPNAALVSTPTGAENFALESAFKPEQTQQAYLASLSR
HCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHH
IQAYLRAGDCYQVNLAQRFSTHFSGSTLSAWLGLQQAHPAPHSCYFQTDDGNSVFGVSPE
HHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHH
RFLSIRNRQVVAEPIKGSRPRGANPEEDGRLAAELRANPKDLAENLMIVDLLRNDLGLSC
HHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
ESGSIQASPLFELRQFSNVQHLVSTITGTLKADITPLEALFRAFPGGSITGAPKQRAMEI
CCCCEECCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
ITELEPVARGAYCGSFFWMDDQENLDSNILIRTMQTDGDRIYCHGGGGIVFDSDPLAEYE
HHHHHHHHCCCEECEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCEEEECCCCHHHHH
ESLFKVEKLMRALEERFL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYPCVFQSEGSLRWLGEPDAVLSAQSLSQLHELRANIEYALANEYCFVAGILPYEVGSA
CCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECCHHHHHHH
LHGLPCAPFTAWAYLYKDAPSQNTPNAALVSTPTGAENFALESAFKPEQTQQAYLASLSR
HCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHH
IQAYLRAGDCYQVNLAQRFSTHFSGSTLSAWLGLQQAHPAPHSCYFQTDDGNSVFGVSPE
HHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHH
RFLSIRNRQVVAEPIKGSRPRGANPEEDGRLAAELRANPKDLAENLMIVDLLRNDLGLSC
HHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
ESGSIQASPLFELRQFSNVQHLVSTITGTLKADITPLEALFRAFPGGSITGAPKQRAMEI
CCCCEECCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
ITELEPVARGAYCGSFFWMDDQENLDSNILIRTMQTDGDRIYCHGGGGIVFDSDPLAEYE
HHHHHHHHCCCEECEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCEEEECCCCHHHHH
ESLFKVEKLMRALEERFL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]