Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 110834075

GI number: 110834075

Start: 1380723

End: 1382654

Strand: Direct

Name: ppiD [H]

Synonym: ABO_1214

Alternate gene names: 110834075

Gene position: 1380723-1382654 (Clockwise)

Preceding gene: 110834074

Following gene: 110834084

Centisome position: 44.25

GC content: 50.47

Gene sequence:

>1932_bases
ATGCAGGAGTTCAGACGGTTTGTCCGCGGTCCCGTGGGCAAGGTCCTGCTTGCCGCTATCATTCTTCCTTTCGTGATTTC
CGGCTTTTATGGCTATTTTGTCGGAGGAAGTACTGGCGATGTGGTAGCTGAAGTTGAAGGTAGTAAGATCACTCGTGGCG
TAGTCAATCAACGGGTTGAGCGGGTTCGTAACATGCTTCGCGAGCAGAGCCCGAACATGAACCCCGCCTTGCTAGATTCC
TTTGTGCGTCCGGAAATGGTGTTGGATGGAATTGTTAACGAGCAATTGATCCTTTCAGCGGCTGAGCAATCAAATATGGT
GTTCAGTGAAAAACAGGTTGCCGCCGATATTTACAAAGTGCCGTTATTTCAAGTAGACGGAAAGTTTTCTGAACAACGAT
TTGAACGTGAGCTGCGCGCCCGTGGCATGAATCCACAAACCTATGTTCAAGGCCTACGTCAGGACATGCTTAAAGAGCAG
TTCCGTGCCGGTTTTATGCAGACGGATTTTTCGCTGCCCTTAGAATTGAACGAGCAGCGTCGTTTGGGTGAACAGTCACG
GGACATTCGCTATGTACAATTGGATATCGATTCTCTGCGCAAGCAATTCACCGTATCGGATGAAGACGTCAAAGCGTTTT
ACGACGACAATCAGGGTGAGTTCATGCGTCCTGAAGAATTCAAGGTTTCCTACGTTGAATTGTCCGCTGATAAGTACACA
GATCAGGTCAGCGTGACTGACGAAGAGGTGGAGGCGGAATACGACGTTCGCAAATCCATTATGGAAGAAGCGGGCGCCGG
TGACGCACGGCGTCATGTGTCGCATATCCTCATCGAATTGAATGATGATCGTGATCTTGATCAGGCAAAGGCCCGTGCCC
GTGAAGCGGCTAAAGCCATTGCAGATGGTGCTTCTTTTGCGGACGTCGCTGCCCAATATTCCGATGATTTAGGCAGTGCC
CAATCCGGTGGTGAGCTGGGCGTGGTATCTAAAGGAGCCTTGCCTGAAGAAATGGAAACAGCGATTGCAGAGTTGTCGCC
TGGAACCGTTTCTGCTCCGGTGGTTACTGATGCAGGTGTGCACCTTATATTCGTAACGCAAGAAGACACTGCGACAGCGT
TGCCGTCATTAGCCGATCTGTCTGATCAGATCCGTGCTGATTTGACTAAAGCCCGAGCAGAATCGTTGCTGAACGAGGAT
GTGTCGAAGCTTGAAGAGCTTCTTTATGAGCATCCAGACCTACAGAGTCCAGCTGAGCAAGTAGGTGTTTCCGTGGTGAC
GACTGATTGGATTGATCTTGCTGCTGCAAATGCACCGTTATCGTTGCCGCAAGTGCAACAGGCTCTTAATTCAGAGCAGG
TTCGTCAGCAAGGCCATAACAGTGATTTAATTGAAGTGGATTCCACGCATTATATCGCTGTGCGTATTGCTGAAGATAAG
CCTGCTGAGCCGATGCCCCTTGACGAGGTTTCTTTTGCCATTCGCGAGCGGTTGAAAGGTGAGCTAGCGATGGACAAAGT
ACAGCAACTGGCAAAAATGGCTGAGAAAACGATCGAGGAAGGTGGCAACCTGGAATCAGTGGCTACATTGTTTGATGTGG
AAATCGCCGAACAGGAAGGCTTGCAACGTGGCGGCGCCGAACCCGCGATGGAAGTGGTAAATGGTGCCTTTAGTGCTCCT
CGCGCTGCAGAAGGTGACGCTTCACCAGTCTCGATTACTCGTTTGGGCAATGGTTCAGTTGTTGCCTATCAGGTAACCAG
TGTCGCAGACGGTAATGCTGAGCCGCTGAGTGCTGCCCAACAGCAGGCAGCTCTTATAGAGCTTGGCAACGTCGAAGGCC
AACGAAACTTCCGTCAGGTGGTTGCTTTACTCCGTGATGAAGGTGATGTGGAACTGTATCCGTCTCGATTGAGTGCCAAT
CAGGGCGAATAA

Upstream 100 bases:

>100_bases
CGTAGCGAGTACGCTTTTTTGCATTATAAGGGAACCCGCAGCAACTTGTCGGTTCTGAATAACAAGGTCCAATTACAGAA
TATCCTTACGGAGTAATTTC

Downstream 100 bases:

>100_bases
TACTCTGAAAGTTCCGCCCACAAAAAAGCCCACCTAAGCGGTGGGCTTTTTTGTGGGCGTTAATAAGTAAGAAAGACGTT
CTTAAAGCTCCAGTTCAAAC

Product: peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MQEFRRFVRGPVGKVLLAAIILPFVISGFYGYFVGGSTGDVVAEVEGSKITRGVVNQRVERVRNMLREQSPNMNPALLDS
FVRPEMVLDGIVNEQLILSAAEQSNMVFSEKQVAADIYKVPLFQVDGKFSEQRFERELRARGMNPQTYVQGLRQDMLKEQ
FRAGFMQTDFSLPLELNEQRRLGEQSRDIRYVQLDIDSLRKQFTVSDEDVKAFYDDNQGEFMRPEEFKVSYVELSADKYT
DQVSVTDEEVEAEYDVRKSIMEEAGAGDARRHVSHILIELNDDRDLDQAKARAREAAKAIADGASFADVAAQYSDDLGSA
QSGGELGVVSKGALPEEMETAIAELSPGTVSAPVVTDAGVHLIFVTQEDTATALPSLADLSDQIRADLTKARAESLLNED
VSKLEELLYEHPDLQSPAEQVGVSVVTTDWIDLAAANAPLSLPQVQQALNSEQVRQQGHNSDLIEVDSTHYIAVRIAEDK
PAEPMPLDEVSFAIRERLKGELAMDKVQQLAKMAEKTIEEGGNLESVATLFDVEIAEQEGLQRGGAEPAMEVVNGAFSAP
RAAEGDASPVSITRLGNGSVVAYQVTSVADGNAEPLSAAQQQAALIELGNVEGQRNFRQVVALLRDEGDVELYPSRLSAN
QGE

Sequences:

>Translated_643_residues
MQEFRRFVRGPVGKVLLAAIILPFVISGFYGYFVGGSTGDVVAEVEGSKITRGVVNQRVERVRNMLREQSPNMNPALLDS
FVRPEMVLDGIVNEQLILSAAEQSNMVFSEKQVAADIYKVPLFQVDGKFSEQRFERELRARGMNPQTYVQGLRQDMLKEQ
FRAGFMQTDFSLPLELNEQRRLGEQSRDIRYVQLDIDSLRKQFTVSDEDVKAFYDDNQGEFMRPEEFKVSYVELSADKYT
DQVSVTDEEVEAEYDVRKSIMEEAGAGDARRHVSHILIELNDDRDLDQAKARAREAAKAIADGASFADVAAQYSDDLGSA
QSGGELGVVSKGALPEEMETAIAELSPGTVSAPVVTDAGVHLIFVTQEDTATALPSLADLSDQIRADLTKARAESLLNED
VSKLEELLYEHPDLQSPAEQVGVSVVTTDWIDLAAANAPLSLPQVQQALNSEQVRQQGHNSDLIEVDSTHYIAVRIAEDK
PAEPMPLDEVSFAIRERLKGELAMDKVQQLAKMAEKTIEEGGNLESVATLFDVEIAEQEGLQRGGAEPAMEVVNGAFSAP
RAAEGDASPVSITRLGNGSVVAYQVTSVADGNAEPLSAAQQQAALIELGNVEGQRNFRQVVALLRDEGDVELYPSRLSAN
QGE
>Mature_643_residues
MQEFRRFVRGPVGKVLLAAIILPFVISGFYGYFVGGSTGDVVAEVEGSKITRGVVNQRVERVRNMLREQSPNMNPALLDS
FVRPEMVLDGIVNEQLILSAAEQSNMVFSEKQVAADIYKVPLFQVDGKFSEQRFERELRARGMNPQTYVQGLRQDMLKEQ
FRAGFMQTDFSLPLELNEQRRLGEQSRDIRYVQLDIDSLRKQFTVSDEDVKAFYDDNQGEFMRPEEFKVSYVELSADKYT
DQVSVTDEEVEAEYDVRKSIMEEAGAGDARRHVSHILIELNDDRDLDQAKARAREAAKAIADGASFADVAAQYSDDLGSA
QSGGELGVVSKGALPEEMETAIAELSPGTVSAPVVTDAGVHLIFVTQEDTATALPSLADLSDQIRADLTKARAESLLNED
VSKLEELLYEHPDLQSPAEQVGVSVVTTDWIDLAAANAPLSLPQVQQALNSEQVRQQGHNSDLIEVDSTHYIAVRIAEDK
PAEPMPLDEVSFAIRERLKGELAMDKVQQLAKMAEKTIEEGGNLESVATLFDVEIAEQEGLQRGGAEPAMEVVNGAFSAP
RAAEGDASPVSITRLGNGSVVAYQVTSVADGNAEPLSAAQQQAALIELGNVEGQRNFRQVVALLRDEGDVELYPSRLSAN
QGE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=648, Percent_Identity=27.1604938271605, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70505; Mature: 70505

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFRRFVRGPVGKVLLAAIILPFVISGFYGYFVGGSTGDVVAEVEGSKITRGVVNQRVE
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHH
RVRNMLREQSPNMNPALLDSFVRPEMVLDGIVNEQLILSAAEQSNMVFSEKQVAADIYKV
HHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
PLFQVDGKFSEQRFERELRARGMNPQTYVQGLRQDMLKEQFRAGFMQTDFSLPLELNEQR
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RLGEQSRDIRYVQLDIDSLRKQFTVSDEDVKAFYDDNQGEFMRPEEFKVSYVELSADKYT
HCCCHHCCCEEEEEEHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHCEEEEEEECCHHCC
DQVSVTDEEVEAEYDVRKSIMEEAGAGDARRHVSHILIELNDDRDLDQAKARAREAAKAI
CCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
ADGASFADVAAQYSDDLGSAQSGGELGVVSKGALPEEMETAIAELSPGTVSAPVVTDAGV
HCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCE
HLIFVTQEDTATALPSLADLSDQIRADLTKARAESLLNEDVSKLEELLYEHPDLQSPAEQ
EEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VGVSVVTTDWIDLAAANAPLSLPQVQQALNSEQVRQQGHNSDLIEVDSTHYIAVRIAEDK
HCEEEEEECHHHHHHCCCCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCEEEEEEEECCC
PAEPMPLDEVSFAIRERLKGELAMDKVQQLAKMAEKTIEEGGNLESVATLFDVEIAEQEG
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LQRGGAEPAMEVVNGAFSAPRAAEGDASPVSITRLGNGSVVAYQVTSVADGNAEPLSAAQ
HHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHH
QQAALIELGNVEGQRNFRQVVALLRDEGDVELYPSRLSANQGE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECHHCCCCCCC
>Mature Secondary Structure
MQEFRRFVRGPVGKVLLAAIILPFVISGFYGYFVGGSTGDVVAEVEGSKITRGVVNQRVE
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHH
RVRNMLREQSPNMNPALLDSFVRPEMVLDGIVNEQLILSAAEQSNMVFSEKQVAADIYKV
HHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
PLFQVDGKFSEQRFERELRARGMNPQTYVQGLRQDMLKEQFRAGFMQTDFSLPLELNEQR
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RLGEQSRDIRYVQLDIDSLRKQFTVSDEDVKAFYDDNQGEFMRPEEFKVSYVELSADKYT
HCCCHHCCCEEEEEEHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHCEEEEEEECCHHCC
DQVSVTDEEVEAEYDVRKSIMEEAGAGDARRHVSHILIELNDDRDLDQAKARAREAAKAI
CCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHH
ADGASFADVAAQYSDDLGSAQSGGELGVVSKGALPEEMETAIAELSPGTVSAPVVTDAGV
HCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEECCCE
HLIFVTQEDTATALPSLADLSDQIRADLTKARAESLLNEDVSKLEELLYEHPDLQSPAEQ
EEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VGVSVVTTDWIDLAAANAPLSLPQVQQALNSEQVRQQGHNSDLIEVDSTHYIAVRIAEDK
HCEEEEEECHHHHHHCCCCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCEEEEEEEECCC
PAEPMPLDEVSFAIRERLKGELAMDKVQQLAKMAEKTIEEGGNLESVATLFDVEIAEQEG
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LQRGGAEPAMEVVNGAFSAPRAAEGDASPVSITRLGNGSVVAYQVTSVADGNAEPLSAAQ
HHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHH
QQAALIELGNVEGQRNFRQVVALLRDEGDVELYPSRLSANQGE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]