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The map label for this gene is lpxB

Identifier: 110834017

GI number: 110834017

Start: 1313306

End: 1314457

Strand: Direct

Name: lpxB

Synonym: ABO_1156

Alternate gene names: 110834017

Gene position: 1313306-1314457 (Clockwise)

Preceding gene: 110834016

Following gene: 110834018

Centisome position: 42.09

GC content: 54.86

Gene sequence:

>1152_bases
ATGACACAGCGTAAGGATGCTCCGCTTGTCGCGCTGATTGCCGGGGAAGCTTCCGGGGATATTTTAGGGGCAGGCCTCAT
GCAGGCCCTTGAAAATCGTTATCCTGGCGCTCGTTTTATTGGTGTGGGTGGCGAGGAGATGGCACAGGCTGGTTTGACTA
GCCTGTTCCCCATGGAAAAATTGTCGGTGATGGGAATCACCGAGGTGCTATCACACCTTCCTGAATTATTACGTCTGCGC
AAATCTCTGGTCCGCTTTCTGCTTGAGCAGCGGCCGGACGTGGTCGTTGGTATCGACTCTCCAGATTTCACCCTGCCAAT
TGCGCGTCGTCTTCATGATCGAGGCTTGAAAACCGTTCATTATGTGAGTCCCTCCGTGTGGGCTTGGCGCCAGGGTCGCA
TTAAAGGCATAAAGAAAAGTATTGATCTGATGCTAACGCTTTTGCCGTTCGAAGCGCGTTTCTATGAGGAGCATGACGTG
CCGGTGGCTTTTGTCGGTCACCCGTTGGCCGATCGTATCCCGCTGGAAACGGATGTGGCTGGGGCCCGCAAGGCTCTGGC
GCTGGACCGCGATGCTCGTATTTTGGCAGTACTACCAGGAAGCCGAGGAGGTGAAGTGGGGCAATTGATGCCCGCTTTCC
TGGACGCTATGGTGGCGCTGAATCACCAGGATCCCACGCTGCAGTATGTGATTCCGGCTGCTAACGCGGCCCGCCGTGAA
CAAATACAGACGTTGCTGAATACGCAGCCTAATTTGCCCGTGTCATTGATCGATGGACAGAGCCGGACGGTGATGGCGGC
GGCGGATGTGGTGCTAATGGCTTCAGGTACAGCCACGCTGGAAGGCTTGTTGCTGAACAAACCGATGGTGGTAGGCTATC
GGGTTGGGGCAGTGACTTACGCCATTGTTAGTCGTCTGATAAAAAGTGAATTTTTTTCCTTGCCCAATTTATTGTGTCGG
CAGGAAATGGTCCCTGAGCTGCTTCAGAGCCAGCTGACCACGGAAGCGATTGTTGCTGCTGTGCGCCGTTGGTTTGATCA
GCCTGAGCAGGCCCAGGCACTAAAAATACAGTTTCAGAGCGTGCATCAACAACTTCGTGGCGGTGCCAGTGAGAAGGCGG
CGGCGGCCGTTGCTCGTTTGTTGGAGGCTTGA

Upstream 100 bases:

>100_bases
GAGCAGGCGTTGCTGGAATTAGAGTCCATGGAGCCGTCGGATGCGCTACAGATTTTTATCGATTCTCTAAAGTCTTCCGA
GCGCGGCATCACGCGCTGAT

Downstream 100 bases:

>100_bases
TGGCAGATACGCAACCCTGCGACCCGTTTGCTGAGTACGGCCTAGCTGATCCGTTTATTCCTTCTGATTTTTTTTGGCAG
CCGGGCATGCTGGTGGCGGG

Product: lipid A disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEKLSVMGITEVLSHLPELLRLR
KSLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVHYVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDV
PVAFVGHPLADRIPLETDVAGARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARRE
QIQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTYAIVSRLIKSEFFSLPNLLCR
QEMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQSVHQQLRGGASEKAAAAVARLLEA

Sequences:

>Translated_383_residues
MTQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEKLSVMGITEVLSHLPELLRLR
KSLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVHYVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDV
PVAFVGHPLADRIPLETDVAGARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARRE
QIQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTYAIVSRLIKSEFFSLPNLLCR
QEMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQSVHQQLRGGASEKAAAAVARLLEA
>Mature_382_residues
TQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEKLSVMGITEVLSHLPELLRLRK
SLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVHYVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDVP
VAFVGHPLADRIPLETDVAGARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARREQ
IQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTYAIVSRLIKSEFFSLPNLLCRQ
EMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQSVHQQLRGGASEKAAAAVARLLEA

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family

Homologues:

Organism=Escherichia coli, GI1786379, Length=382, Percent_Identity=46.5968586387435, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXB_ALCBS (Q0VQE4)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692876.1
- ProteinModelPortal:   Q0VQE4
- STRING:   Q0VQE4
- GeneID:   4211461
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1156
- NMPDR:   fig|393595.12.peg.1167
- eggNOG:   COG0763
- HOGENOM:   HBG584837
- OMA:   DFTHRVA
- PhylomeDB:   Q0VQE4
- BioCyc:   ABOR393595:ABO_1156-MONOMER
- HAMAP:   MF_00392
- InterPro:   IPR003835
- TIGRFAMs:   TIGR00215

Pfam domain/function: PF02684 LpxB

EC number: =2.4.1.182

Molecular weight: Translated: 41810; Mature: 41679

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEK
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHHH
LSVMGITEVLSHLPELLRLRKSLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEEE
YVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDVPVAFVGHPLADRIPLETDVA
ECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHH
GARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARRE
HHHHHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
QIQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTY
HHHHHHCCCCCCCEEEECCCCCEEEEECCEEEEECCCHHHHHHHCCCCEEEEEEHHHHHH
AIVSRLIKSEFFSLPNLLCRQEMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VHQQLRGGASEKAAAAVARLLEA
HHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEK
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCHHH
LSVMGITEVLSHLPELLRLRKSLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEEE
YVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDVPVAFVGHPLADRIPLETDVA
ECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHH
GARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARRE
HHHHHHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
QIQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTY
HHHHHHCCCCCCCEEEECCCCCEEEEECCEEEEECCCHHHHHHHCCCCEEEEEEHHHHHH
AIVSRLIKSEFFSLPNLLCRQEMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VHQQLRGGASEKAAAAVARLLEA
HHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA