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The map label for this gene is rnhB

Identifier: 110834018

GI number: 110834018

Start: 1314457

End: 1315119

Strand: Direct

Name: rnhB

Synonym: ABO_1157

Alternate gene names: 110834018

Gene position: 1314457-1315119 (Clockwise)

Preceding gene: 110834017

Following gene: 110834019

Centisome position: 42.13

GC content: 57.16

Gene sequence:

>663_bases
ATGGCAGATACGCAACCCTGCGACCCGTTTGCTGAGTACGGCCTAGCTGATCCGTTTATTCCTTCTGATTTTTTTTGGCA
GCCGGGCATGCTGGTGGCGGGTGTCGACGAAGTGGGTCGAGGCCCGTTAGTGGGTGCGGTAGTCACCGCGGCAGTGATAT
TGGACCCAAAGTACCCGATCGTCGGCTTGGCTGATTCCAAAAAAATCAGTGAAAAGAAACGTCTGGCGCTGGAGTCTGAG
ATTAAGTCTCACGCGCTTGGCTGGGCGTTGGGGCGAGCAGAGTCGGATGAAATTGACCAACTGAACATTCTGCATGCCAC
CATGCTGGCCATGCAGCGGGCAGTGGCAGCGCTGCCTGTGGAGGCGCATGCTGTACTGATTGATGGTAATCGAGTACCGG
CGTTGCAGTGTCCGGCGCAGGCGGTAGTAAAAGGGGATGGGCGTGTACCGGCTATCTCTGCTGCCTCAATTCTTGCCAAA
GTGGCGCGGGACCGCGAAATGTATGCCTTGCATGCCCGTTATCCCCAATACGGCTTCGACCGCCATAAAGGCTACCCAAC
TGCGGTGCATATGGCGGCCCTAGAACAGCATGGCGCCTTGGCCGAGCATCGTCGCTCCTTTGGCCCGGTGGCTGCTGCAA
TTGCACAAGGGAACCTGTTTTGA

Upstream 100 bases:

>100_bases
CCCAGGCACTAAAAATACAGTTTCAGAGCGTGCATCAACAACTTCGTGGCGGTGCCAGTGAGAAGGCGGCGGCGGCCGTT
GCTCGTTTGTTGGAGGCTTG

Downstream 100 bases:

>100_bases
CTGATCCCCGTTTTGTCCACCTGCGCCTTCATACCGATTATTCACTGGTTGATGGAATCGTTCGGGTTAAGGAACTGACC
AAGACCTGCGTAAATGAGCA

Product: ribonuclease H

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MADTQPCDPFAEYGLADPFIPSDFFWQPGMLVAGVDEVGRGPLVGAVVTAAVILDPKYPIVGLADSKKISEKKRLALESE
IKSHALGWALGRAESDEIDQLNILHATMLAMQRAVAALPVEAHAVLIDGNRVPALQCPAQAVVKGDGRVPAISAASILAK
VARDREMYALHARYPQYGFDRHKGYPTAVHMAALEQHGALAEHRRSFGPVAAAIAQGNLF

Sequences:

>Translated_220_residues
MADTQPCDPFAEYGLADPFIPSDFFWQPGMLVAGVDEVGRGPLVGAVVTAAVILDPKYPIVGLADSKKISEKKRLALESE
IKSHALGWALGRAESDEIDQLNILHATMLAMQRAVAALPVEAHAVLIDGNRVPALQCPAQAVVKGDGRVPAISAASILAK
VARDREMYALHARYPQYGFDRHKGYPTAVHMAALEQHGALAEHRRSFGPVAAAIAQGNLF
>Mature_219_residues
ADTQPCDPFAEYGLADPFIPSDFFWQPGMLVAGVDEVGRGPLVGAVVTAAVILDPKYPIVGLADSKKISEKKRLALESEI
KSHALGWALGRAESDEIDQLNILHATMLAMQRAVAALPVEAHAVLIDGNRVPALQCPAQAVVKGDGRVPAISAASILAKV
ARDREMYALHARYPQYGFDRHKGYPTAVHMAALEQHGALAEHRRSFGPVAAAIAQGNLF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=192, Percent_Identity=70.3125, Blast_Score=260, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_ALCBS (Q0VQE3)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692877.1
- ProteinModelPortal:   Q0VQE3
- SMR:   Q0VQE3
- STRING:   Q0VQE3
- GeneID:   4212167
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1157
- NMPDR:   fig|393595.12.peg.1168
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q0VQE3
- BioCyc:   ABOR393595:ABO_1157-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23538; Mature: 23407

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTQPCDPFAEYGLADPFIPSDFFWQPGMLVAGVDEVGRGPLVGAVVTAAVILDPKYPI
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHCCCCHHHHHHHHHHHCCCCCCE
VGLADSKKISEKKRLALESEIKSHALGWALGRAESDEIDQLNILHATMLAMQRAVAALPV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
EAHAVLIDGNRVPALQCPAQAVVKGDGRVPAISAASILAKVARDREMYALHARYPQYGFD
EEEEEEEECCCCCCEECCHHHHEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
RHKGYPTAVHMAALEQHGALAEHRRSFGPVAAAIAQGNLF
HCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure 
ADTQPCDPFAEYGLADPFIPSDFFWQPGMLVAGVDEVGRGPLVGAVVTAAVILDPKYPI
CCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHCCCCHHHHHHHHHHHCCCCCCE
VGLADSKKISEKKRLALESEIKSHALGWALGRAESDEIDQLNILHATMLAMQRAVAALPV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
EAHAVLIDGNRVPALQCPAQAVVKGDGRVPAISAASILAKVARDREMYALHARYPQYGFD
EEEEEEEECCCCCCEECCHHHHEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
RHKGYPTAVHMAALEQHGALAEHRRSFGPVAAAIAQGNLF
HCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA