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The map label for this gene is galE [H]

Identifier: 110833799

GI number: 110833799

Start: 1051509

End: 1052441

Strand: Direct

Name: galE [H]

Synonym: ABO_0938

Alternate gene names: 110833799

Gene position: 1051509-1052441 (Clockwise)

Preceding gene: 110833798

Following gene: 110833800

Centisome position: 33.7

GC content: 53.38

Gene sequence:

>933_bases
GTGCTTGATAACCTCACCAATAGCAGCGAGGAGAGCCTACGCCGTGTCCAAAGGTTAACTGGGCGTGAGCTGACTTTCAT
TAAAGGCGACATTCGCGATGCGGATTGCCTAGATCGACTTTTCGCCGACCATGATATCGATTCCGTGATCCATTTTGCTG
GCCTGAAGGCGGTGGGTGAATCGGTTGAGCAGCCATTGCAATACTACGATTGCAATGTGGTAGGCACGGTGCGTTTGTTG
GAAGCCATGGAGCGGGCAGGGGTGCGAACTCTGGTATTTAGCTCATCGGCAACGGTGTACGGGGACCCGGCCTCTGTGCC
CATTAAGGAAAACTTTCCTCTTAGTGCGACCAATCCCTATGGTGCCAGTAAGTTGCACATTGAAGATATGCTCCGTGATC
TCTACTCCAGCGATAACCGGTGGCAGGTGGCGTTACTGCGCTATTTTAATCCTGTGGGCGCCCATGAAAGTGGCGAAATA
GGTGAGGACCCTAATGGTATTCCCAATAACCTCATGCCGTTTATTGCACAGGTTGCCATTGGCAAGCGAGCACAGCTGAG
TGTTTTTGGTGGAGATTATGCGACGCCGGATGGCACTGGAGTGAGGGATTATATCCATGTGATGGATTTAGCCCAGGGAC
ATTTGGCGGCACTGCAGGCTTTAGAGGGCGATCGTGGTCTGCTGACGGTGAATTTGGGAACCGGGCGAGGCTACAGTGTG
CTGGAAATGATTGCGGCCTTTTCTAAGGCCAGCGGGCGAGACGTTCCCTACCAGATTGTGGAACGTCGATCGGGAGATGT
GGCTACCTGTTACGCGGATCCTGCCCATGCAGAAGAAGTCATCGGGTGGAAGGCTGCCCGCGGCATTGATGATATGTGCT
GTGACCACTGGCGTTGGCAGGAAAGTAATCCTGAAGGGTATGGCGAGAGATAG

Upstream 100 bases:

>100_bases
AGGATGATGAATCATGAGCAAAGTATTGGTCACCGGCGGAGCCGGTTATATCGGCTCTCACACGGTGCTGTTGCTGCTTG
AAGCTGGGCGCGAGGTTGTC

Downstream 100 bases:

>100_bases
GGAGCTATCGCTGACTGAATGAGTGCTTTCCAAGCTTCTGTTTTACGGTTCTATATAAAGAGAGTGGGTTGGGAACATGC
TCAAATCAGTTTTATATAAA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLDNLTNSSEESLRRVQRLTGRELTFIKGDIRDADCLDRLFADHDIDSVIHFAGLKAVGESVEQPLQYYDCNVVGTVRLL
EAMERAGVRTLVFSSSATVYGDPASVPIKENFPLSATNPYGASKLHIEDMLRDLYSSDNRWQVALLRYFNPVGAHESGEI
GEDPNGIPNNLMPFIAQVAIGKRAQLSVFGGDYATPDGTGVRDYIHVMDLAQGHLAALQALEGDRGLLTVNLGTGRGYSV
LEMIAAFSKASGRDVPYQIVERRSGDVATCYADPAHAEEVIGWKAARGIDDMCCDHWRWQESNPEGYGER

Sequences:

>Translated_310_residues
MLDNLTNSSEESLRRVQRLTGRELTFIKGDIRDADCLDRLFADHDIDSVIHFAGLKAVGESVEQPLQYYDCNVVGTVRLL
EAMERAGVRTLVFSSSATVYGDPASVPIKENFPLSATNPYGASKLHIEDMLRDLYSSDNRWQVALLRYFNPVGAHESGEI
GEDPNGIPNNLMPFIAQVAIGKRAQLSVFGGDYATPDGTGVRDYIHVMDLAQGHLAALQALEGDRGLLTVNLGTGRGYSV
LEMIAAFSKASGRDVPYQIVERRSGDVATCYADPAHAEEVIGWKAARGIDDMCCDHWRWQESNPEGYGER
>Mature_310_residues
MLDNLTNSSEESLRRVQRLTGRELTFIKGDIRDADCLDRLFADHDIDSVIHFAGLKAVGESVEQPLQYYDCNVVGTVRLL
EAMERAGVRTLVFSSSATVYGDPASVPIKENFPLSATNPYGASKLHIEDMLRDLYSSDNRWQVALLRYFNPVGAHESGEI
GEDPNGIPNNLMPFIAQVAIGKRAQLSVFGGDYATPDGTGVRDYIHVMDLAQGHLAALQALEGDRGLLTVNLGTGRGYSV
LEMIAAFSKASGRDVPYQIVERRSGDVATCYADPAHAEEVIGWKAARGIDDMCCDHWRWQESNPEGYGER

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=317, Percent_Identity=58.9905362776025, Blast_Score=387, Evalue=1e-108,
Organism=Homo sapiens, GI56118217, Length=317, Percent_Identity=58.9905362776025, Blast_Score=387, Evalue=1e-108,
Organism=Homo sapiens, GI189083684, Length=317, Percent_Identity=58.9905362776025, Blast_Score=387, Evalue=1e-108,
Organism=Homo sapiens, GI7657641, Length=234, Percent_Identity=26.4957264957265, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786974, Length=308, Percent_Identity=54.2207792207792, Blast_Score=354, Evalue=3e-99,
Organism=Escherichia coli, GI48994969, Length=268, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788353, Length=346, Percent_Identity=24.8554913294798, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=316, Percent_Identity=49.6835443037975, Blast_Score=326, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI71982038, Length=300, Percent_Identity=50.6666666666667, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17568069, Length=225, Percent_Identity=28.4444444444444, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=317, Percent_Identity=52.6813880126183, Blast_Score=338, Evalue=7e-94,
Organism=Drosophila melanogaster, GI19923002, Length=318, Percent_Identity=56.6037735849057, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34100; Mature: 34100

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLTNSSEESLRRVQRLTGRELTFIKGDIRDADCLDRLFADHDIDSVIHFAGLKAVGE
CCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
SVEQPLQYYDCNVVGTVRLLEAMERAGVRTLVFSSSATVYGDPASVPIKENFPLSATNPY
HHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC
GASKLHIEDMLRDLYSSDNRWQVALLRYFNPVGAHESGEIGEDPNGIPNNLMPFIAQVAI
CCCEEEHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GKRAQLSVFGGDYATPDGTGVRDYIHVMDLAQGHLAALQALEGDRGLLTVNLGTGRGYSV
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LEMIAAFSKASGRDVPYQIVERRSGDVATCYADPAHAEEVIGWKAARGIDDMCCDHWRWQ
HHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCCCCCC
ESNPEGYGER
CCCCCCCCCC
>Mature Secondary Structure
MLDNLTNSSEESLRRVQRLTGRELTFIKGDIRDADCLDRLFADHDIDSVIHFAGLKAVGE
CCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
SVEQPLQYYDCNVVGTVRLLEAMERAGVRTLVFSSSATVYGDPASVPIKENFPLSATNPY
HHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC
GASKLHIEDMLRDLYSSDNRWQVALLRYFNPVGAHESGEIGEDPNGIPNNLMPFIAQVAI
CCCEEEHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GKRAQLSVFGGDYATPDGTGVRDYIHVMDLAQGHLAALQALEGDRGLLTVNLGTGRGYSV
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LEMIAAFSKASGRDVPYQIVERRSGDVATCYADPAHAEEVIGWKAARGIDDMCCDHWRWQ
HHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCCCCCC
ESNPEGYGER
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]