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The map label for this gene is ccmA

Identifier: 110833731

GI number: 110833731

Start: 966863

End: 967516

Strand: Direct

Name: ccmA

Synonym: ABO_0870

Alternate gene names: 110833731

Gene position: 966863-967516 (Clockwise)

Preceding gene: 110833723

Following gene: 110833732

Centisome position: 30.99

GC content: 60.7

Gene sequence:

>654_bases
TTGAGCCAGCCAGCCACCCATTCTGACGCCGAACCCGCCACCCGCTTGGTGCTTGAGCAGCTCAGCTGCGAGCGCGATGA
TCGGTTGTTGTTCAGTGGTTTGAGTTTCACCGCATCGGCTGGTGAAATCTGGCAGATTACCGGGGCCAACGGGGCAGGTA
AGACCACGCTGTTGCGGATTCTGGTGGGGCTCCATGGCTTCTATGAGGGTGAGCGCCAGTGGTGGCAGCCTCAGTGGCAG
CAGCAATTACTGTACTTGGGGCATGAGCCTGGGGTACGTGAAGAGCTAAATCCACTGGAAAATCTGCGTTACGCTTGTGC
GTTAAGCCAGCAGGGGGGAGACCCCATGGCGGCGCTGGCTGCCGTGGGGCTGCAAGGTTTTGAGGAGGTGCCGGCGGCAC
ACCTGTCTGCTGGGCAAAAGCGTCGCATTGCCTTGGCGCGTCTGTGGCTAGACCGTAAAGCCGTGTGGGTGCTCGATGAG
CCCTATACTGCCATCGATCAAGATGGGGTGGCGGCGCTGGACCAGCAAATCCAGCAGGCGGCTGAAGCGGGCACCTTGGT
GATTTATACCTCTCACCACCAGGTTGGCGATGGCGTGCGGCGATTACATCTGGCCCACGGGCAGGCAGAAGTGACGGAAG
GGGGGCGGGTATGA

Upstream 100 bases:

>100_bases
TCCCATGTTAAGGCTTACAGCCTAGATCGGCTTATTAGCGTCGAGCAAGCCCGTTTTGAACTGTCGTGCTATACTGCTGC
GCTGTTTTAGGGAGCCCGAT

Downstream 100 bases:

>100_bases
GCGTGTTTCGCGCGGCGCTGTCCCGTGAGTTGCTGGTGCTGTGGCGTAGCCCGGCAGAAATCATCAATCCGTTGTTTTTC
TTTGTCATGGTGATCAGCCT

Product: Heme exporter protein A

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSQPATHSDAEPATRLVLEQLSCERDDRLLFSGLSFTASAGEIWQITGANGAGKTTLLRILVGLHGFYEGERQWWQPQWQ
QQLLYLGHEPGVREELNPLENLRYACALSQQGGDPMAALAAVGLQGFEEVPAAHLSAGQKRRIALARLWLDRKAVWVLDE
PYTAIDQDGVAALDQQIQQAAEAGTLVIYTSHHQVGDGVRRLHLAHGQAEVTEGGRV

Sequences:

>Translated_217_residues
MSQPATHSDAEPATRLVLEQLSCERDDRLLFSGLSFTASAGEIWQITGANGAGKTTLLRILVGLHGFYEGERQWWQPQWQ
QQLLYLGHEPGVREELNPLENLRYACALSQQGGDPMAALAAVGLQGFEEVPAAHLSAGQKRRIALARLWLDRKAVWVLDE
PYTAIDQDGVAALDQQIQQAAEAGTLVIYTSHHQVGDGVRRLHLAHGQAEVTEGGRV
>Mature_216_residues
SQPATHSDAEPATRLVLEQLSCERDDRLLFSGLSFTASAGEIWQITGANGAGKTTLLRILVGLHGFYEGERQWWQPQWQQ
QLLYLGHEPGVREELNPLENLRYACALSQQGGDPMAALAAVGLQGFEEVPAAHLSAGQKRRIALARLWLDRKAVWVLDEP
YTAIDQDGVAALDQQIQQAAEAGTLVIYTSHHQVGDGVRRLHLAHGQAEVTEGGRV

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Escherichia coli, GI87082064, Length=203, Percent_Identity=49.7536945812808, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87081709, Length=197, Percent_Identity=25.8883248730964, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787041, Length=183, Percent_Identity=27.8688524590164, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=174, Percent_Identity=24.7126436781609, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_ALCBS (Q0VR80)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692590.1
- ProteinModelPortal:   Q0VR80
- STRING:   Q0VR80
- GeneID:   4212964
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0870
- NMPDR:   fig|393595.12.peg.874
- eggNOG:   COG4133
- HOGENOM:   HBG758042
- OMA:   ARLWHND
- PhylomeDB:   Q0VR80
- BioCyc:   ABOR393595:ABO_0870-MONOMER
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 23794; Mature: 23663

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPATHSDAEPATRLVLEQLSCERDDRLLFSGLSFTASAGEIWQITGANGAGKTTLLRI
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHH
LVGLHGFYEGERQWWQPQWQQQLLYLGHEPGVREELNPLENLRYACALSQQGGDPMAALA
HHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCCCCHHHHHH
AVGLQGFEEVPAAHLSAGQKRRIALARLWLDRKAVWVLDEPYTAIDQDGVAALDQQIQQA
HHHHCCHHHCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHCCCCCHHHHHHHHHHH
AEAGTLVIYTSHHQVGDGVRRLHLAHGQAEVTEGGRV
HHCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SQPATHSDAEPATRLVLEQLSCERDDRLLFSGLSFTASAGEIWQITGANGAGKTTLLRI
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHH
LVGLHGFYEGERQWWQPQWQQQLLYLGHEPGVREELNPLENLRYACALSQQGGDPMAALA
HHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCCCCHHHHHH
AVGLQGFEEVPAAHLSAGQKRRIALARLWLDRKAVWVLDEPYTAIDQDGVAALDQQIQQA
HHHHCCHHHCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHCCCCCHHHHHHHHHHH
AEAGTLVIYTSHHQVGDGVRRLHLAHGQAEVTEGGRV
HHCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA