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The map label for this gene is oadA [H]

Identifier: 110833705

GI number: 110833705

Start: 939033

End: 940832

Strand: Direct

Name: oadA [H]

Synonym: ABO_0844

Alternate gene names: 110833705

Gene position: 939033-940832 (Clockwise)

Preceding gene: 110833704

Following gene: 110833706

Centisome position: 30.1

GC content: 57.72

Gene sequence:

>1800_bases
ATGAGTGACCTGAAACCGTTGGGCATTACTGATGTGGTGTTACGCGATGCGCACCAATCCCTGTTTGCCACCCGTATGCG
TTTGGATGACATGTTGCCGATTGCCGCGGAACTGGATGACATTGGCTTCTGGTCGTTGGAATCCTGGGGTGGGGCGACCT
TTGACGCCTGTATCCGTTATCTGGGTGAAGATCCTTGGCAACGTATCCGAGAATTGAAACAGGCCATGCCGAAAACGCCG
CAGCAAATGTTGCTGCGCGGCCAAAACCTGCTGGGCTATCGCCACTACGCGGATGATGTGGTGGATACCTTTGTGGAGCG
GGCAGCAGAAAACGGCGTGGACGTGTTTCGTGTGTTTGATGCCATGAACGACATGCGCAACATTGAACGGGCCATCGCCG
CCGTGGTGAAACAGGGCAAGCACGCCCAGGGCACCATCGCCTACACGGTCAGCCCGGTTCATACTTTGGATATGTGGGTG
GAGCAGGGCAAAGTTATCGAACAGATGGGGGCCCACTCGGTTGCCATTAAAGACATGGCCGGGCTGTTGCGGCCTGCGGT
GGCGTATGAACTGGTGACTCGCTTGAAAGCGGCCCTGAATATTCCCGTGCACATGCAGTCTCACGCCACCACTGGGCTGT
CCACGGCCACGGCGTTGAAAGCGGCGGAGGCGGGTATCGATAACGTGGATACGGCCATTTCGTCCATGTCGATGACCTAC
GGCCACAGCCCTACAGAATCAGTGGTGGCCATGCTGGAAGGTACGGACCGGGATACCGGATTGGATATCAAAAAGCTGAC
CCGTATTGCCGGGTATTTTCGTGAGGTGCGTAAAAAGTACGCCGCCTTCGAGGGTAGCTTGCGTGGAGTGGATGCACGCA
TCCTGGTGGCACAGGTGCCGGGCGGCATGCTGACCAACATGGAAAGCCAGCTGAAAGAGCAGGGCGCGGCGGACCGATTC
GATGAAGTGCTGAAGGAAATTCCCGTCGTTCGCGAGGACCTGGGCTTTATTCCCCTGGTGACGCCTACTTCGCAAATCGT
CGGCACCCAAGCAGTGCTTAATGTGCTTTCCGGCGAGCGCTACAAAGTCCTCAGCAAGGAAACCCGCGGCATTCTGCGTG
GTGAATATGGCGCTGCTCCCGCGCCGTACAATGCCGAATTGCAGCAGCGAGCGTTGGATGGCGATGAGCCGGTCACCTGC
CGCCCCGGTGACTTGCTCGACAACGAAATGGACAGCCTGCGTGACGAAGTGCTGTGCTTGGCAAAAGACAAAGGCCTGAC
GCTGGAGGAAGGGCCGCGGTTAACCGATGACGTGCTCACCTACGCGCTGTTCCCGCAAATTGGCCAACGTTTTCTGGAAA
ACCGTGGCGATGCCTCGGCGTTTGAGGCGGCGCCCAATGAACGCGGTGCAAACACGTGTGATAGCGCTCAGGCTGAAGGC
GTTTACACCGTGGAAGTGGATGGCCAGCAGTACACGGTAAAAGTGAACGAGGGCGGAGATGTCACCGGCCTGCGTGAAAT
GGGAGACCGGGCCGATCAAACGGCTACCGCCGCGCCCGCCGCAAACCCGGCCAACAGTGTGTCGGTGGCTGCGCCGTTAG
CCGGAAATATTTTTCAGGTACTGGTAAAGCCTGGCGATCAGATCAGCGAAGGGCAAAAAATCATGGTGTTGGAAGCCATG
AAAATGGAAACCGATGTGTCCAGTACCTGTGCCGGTGTGGTCAGCGAGGTTATTGTGAAAGAGGGCGATGCCGTGACTGT
GGGGCAAGCCTTGCTCAGCGTGGAGCCTGCCCATGGATAA

Upstream 100 bases:

>100_bases
CCCTTCTCAAGATTTGCCGCCGCCGGCAATCATCAAAGCGATCGAAAAAGCGGTGCAGCAGCACCGTCAGACTTCTCTGT
CATAGATACCGGATTATTCC

Downstream 100 bases:

>100_bases
GCTGCAAACCCTTTGGCACAGCACCGGGCTGTTTCACATGAGCGGCGGCCAGTTAGTCATGTTGCTGGTTTGTCTGGTGT
TGTTGTGGTTGGCGATTCAC

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MSDLKPLGITDVVLRDAHQSLFATRMRLDDMLPIAAELDDIGFWSLESWGGATFDACIRYLGEDPWQRIRELKQAMPKTP
QQMLLRGQNLLGYRHYADDVVDTFVERAAENGVDVFRVFDAMNDMRNIERAIAAVVKQGKHAQGTIAYTVSPVHTLDMWV
EQGKVIEQMGAHSVAIKDMAGLLRPAVAYELVTRLKAALNIPVHMQSHATTGLSTATALKAAEAGIDNVDTAISSMSMTY
GHSPTESVVAMLEGTDRDTGLDIKKLTRIAGYFREVRKKYAAFEGSLRGVDARILVAQVPGGMLTNMESQLKEQGAADRF
DEVLKEIPVVREDLGFIPLVTPTSQIVGTQAVLNVLSGERYKVLSKETRGILRGEYGAAPAPYNAELQQRALDGDEPVTC
RPGDLLDNEMDSLRDEVLCLAKDKGLTLEEGPRLTDDVLTYALFPQIGQRFLENRGDASAFEAAPNERGANTCDSAQAEG
VYTVEVDGQQYTVKVNEGGDVTGLREMGDRADQTATAAPAANPANSVSVAAPLAGNIFQVLVKPGDQISEGQKIMVLEAM
KMETDVSSTCAGVVSEVIVKEGDAVTVGQALLSVEPAHG

Sequences:

>Translated_599_residues
MSDLKPLGITDVVLRDAHQSLFATRMRLDDMLPIAAELDDIGFWSLESWGGATFDACIRYLGEDPWQRIRELKQAMPKTP
QQMLLRGQNLLGYRHYADDVVDTFVERAAENGVDVFRVFDAMNDMRNIERAIAAVVKQGKHAQGTIAYTVSPVHTLDMWV
EQGKVIEQMGAHSVAIKDMAGLLRPAVAYELVTRLKAALNIPVHMQSHATTGLSTATALKAAEAGIDNVDTAISSMSMTY
GHSPTESVVAMLEGTDRDTGLDIKKLTRIAGYFREVRKKYAAFEGSLRGVDARILVAQVPGGMLTNMESQLKEQGAADRF
DEVLKEIPVVREDLGFIPLVTPTSQIVGTQAVLNVLSGERYKVLSKETRGILRGEYGAAPAPYNAELQQRALDGDEPVTC
RPGDLLDNEMDSLRDEVLCLAKDKGLTLEEGPRLTDDVLTYALFPQIGQRFLENRGDASAFEAAPNERGANTCDSAQAEG
VYTVEVDGQQYTVKVNEGGDVTGLREMGDRADQTATAAPAANPANSVSVAAPLAGNIFQVLVKPGDQISEGQKIMVLEAM
KMETDVSSTCAGVVSEVIVKEGDAVTVGQALLSVEPAHG
>Mature_598_residues
SDLKPLGITDVVLRDAHQSLFATRMRLDDMLPIAAELDDIGFWSLESWGGATFDACIRYLGEDPWQRIRELKQAMPKTPQ
QMLLRGQNLLGYRHYADDVVDTFVERAAENGVDVFRVFDAMNDMRNIERAIAAVVKQGKHAQGTIAYTVSPVHTLDMWVE
QGKVIEQMGAHSVAIKDMAGLLRPAVAYELVTRLKAALNIPVHMQSHATTGLSTATALKAAEAGIDNVDTAISSMSMTYG
HSPTESVVAMLEGTDRDTGLDIKKLTRIAGYFREVRKKYAAFEGSLRGVDARILVAQVPGGMLTNMESQLKEQGAADRFD
EVLKEIPVVREDLGFIPLVTPTSQIVGTQAVLNVLSGERYKVLSKETRGILRGEYGAAPAPYNAELQQRALDGDEPVTCR
PGDLLDNEMDSLRDEVLCLAKDKGLTLEEGPRLTDDVLTYALFPQIGQRFLENRGDASAFEAAPNERGANTCDSAQAEGV
YTVEVDGQQYTVKVNEGGDVTGLREMGDRADQTATAAPAANPANSVSVAAPLAGNIFQVLVKPGDQISEGQKIMVLEAMK
METDVSSTCAGVVSEVIVKEGDAVTVGQALLSVEPAHG

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=636, Percent_Identity=31.2893081761006, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI106049295, Length=636, Percent_Identity=31.2893081761006, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI106049292, Length=636, Percent_Identity=31.2893081761006, Blast_Score=260, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17562816, Length=627, Percent_Identity=33.3333333333333, Blast_Score=310, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6319695, Length=626, Percent_Identity=33.0670926517572, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6321376, Length=626, Percent_Identity=32.9073482428115, Blast_Score=317, Evalue=3e-87,
Organism=Drosophila melanogaster, GI281363050, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24652224, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24652222, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24652220, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24652218, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24652212, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24652210, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24652214, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI19921944, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24652216, Length=626, Percent_Identity=34.6645367412141, Blast_Score=308, Evalue=9e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 64812; Mature: 64681

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKPLGITDVVLRDAHQSLFATRMRLDDMLPIAAELDDIGFWSLESWGGATFDACIRY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCCCHHHHHHH
LGEDPWQRIRELKQAMPKTPQQMLLRGQNLLGYRHYADDVVDTFVERAAENGVDVFRVFD
HCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AMNDMRNIERAIAAVVKQGKHAQGTIAYTVSPVHTLDMWVEQGKVIEQMGAHSVAIKDMA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GLLRPAVAYELVTRLKAALNIPVHMQSHATTGLSTATALKAAEAGIDNVDTAISSMSMTY
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GHSPTESVVAMLEGTDRDTGLDIKKLTRIAGYFREVRKKYAAFEGSLRGVDARILVAQVP
CCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
GGMLTNMESQLKEQGAADRFDEVLKEIPVVREDLGFIPLVTPTSQIVGTQAVLNVLSGER
CCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCC
YKVLSKETRGILRGEYGAAPAPYNAELQQRALDGDEPVTCRPGDLLDNEMDSLRDEVLCL
EEHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEE
AKDKGLTLEEGPRLTDDVLTYALFPQIGQRFLENRGDASAFEAAPNERGANTCDSAQAEG
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCC
VYTVEVDGQQYTVKVNEGGDVTGLREMGDRADQTATAAPAANPANSVSVAAPLAGNIFQV
EEEEEECCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCCCCCCCCCCEEECCHHHHHHHH
LVKPGDQISEGQKIMVLEAMKMETDVSSTCAGVVSEVIVKEGDAVTVGQALLSVEPAHG
HHCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCC
>Mature Secondary Structure 
SDLKPLGITDVVLRDAHQSLFATRMRLDDMLPIAAELDDIGFWSLESWGGATFDACIRY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCCCCCHHHHHHH
LGEDPWQRIRELKQAMPKTPQQMLLRGQNLLGYRHYADDVVDTFVERAAENGVDVFRVFD
HCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AMNDMRNIERAIAAVVKQGKHAQGTIAYTVSPVHTLDMWVEQGKVIEQMGAHSVAIKDMA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GLLRPAVAYELVTRLKAALNIPVHMQSHATTGLSTATALKAAEAGIDNVDTAISSMSMTY
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GHSPTESVVAMLEGTDRDTGLDIKKLTRIAGYFREVRKKYAAFEGSLRGVDARILVAQVP
CCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
GGMLTNMESQLKEQGAADRFDEVLKEIPVVREDLGFIPLVTPTSQIVGTQAVLNVLSGER
CCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCC
YKVLSKETRGILRGEYGAAPAPYNAELQQRALDGDEPVTCRPGDLLDNEMDSLRDEVLCL
EEHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEE
AKDKGLTLEEGPRLTDDVLTYALFPQIGQRFLENRGDASAFEAAPNERGANTCDSAQAEG
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCC
VYTVEVDGQQYTVKVNEGGDVTGLREMGDRADQTATAAPAANPANSVSVAAPLAGNIFQV
EEEEEECCCEEEEEECCCCCCCHHHHHCCHHHCCCCCCCCCCCCCCCEEECCHHHHHHHH
LVKPGDQISEGQKIMVLEAMKMETDVSSTCAGVVSEVIVKEGDAVTVGQALLSVEPAHG
HHCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]