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The map label for this gene is dsbC [H]

Identifier: 110833665

GI number: 110833665

Start: 896231

End: 896974

Strand: Direct

Name: dsbC [H]

Synonym: ABO_0804

Alternate gene names: 110833665

Gene position: 896231-896974 (Clockwise)

Preceding gene: 110833664

Following gene: 110833666

Centisome position: 28.72

GC content: 52.82

Gene sequence:

>744_bases
ATGAAAAAAGGTTTGCTGTTTGTATTATTGGGGCTGATGACCGCCTGTGGGGCCAGTTCTGAAGGTAATAAAGGGAACGC
CGAAATCGATGGTGATCAAGCCAAAGCGGCGTTCGAGAACGCTTTTGACGGGGTTGAAGTCAGTGATGTGCGCGCTGCCC
CCATGGCGGGCATGCTTGAGCTTGAAGTGAACGGTGGTGAAACCGTTTATATGAGTGAGAATGGCCGCTTTGTGATGGTC
GGTAAGTTGCTGGAGCTAAAAGACGGGGAGGTGATCAACCCGGCCGAGCAGCGACTAGAAAAAGTTCGCGCCGACGGCAT
CAAGACGTTAAACAAGGACGACATGATCTCTTACGTGGCGCCTGAAGAGACAGCAGAAGTGTATGTGTTCACTGATATTA
CCTGCGGATATTGCCGTAAATTGCACCGCCATATTGAGGAATACATGGACTCGGGCGTGACTGTCCATTACCTGGCCTTC
CCTCGTGGTGGCCCTACCACCAAGGCAGCAGCGGCCATGCGCCATATCTGGTGCGCAGAAGATCGCCTTCAAGCACTGAC
CGATGCCAAGCTCAACGAAAAGGTTAGCGATGCCGAGCTGGGTGAGTGTGCCAAGCCAGTGGATGAGCAATACCCATTGG
GCTTGAAATTTGGGGTGCGTGGTACACCGGCAATCTATACCTCTGAGGGCAAGCAACTGGGGGGGTATTTACCACCGAAA
GATTTGCTCAAGCGACTGAACTGA

Upstream 100 bases:

>100_bases
GCAGCAGCGGTTACAAGACGTATACCAGAAACATCACCCTCGATCGGGAACTTGAGCCTGTTGGCGGGTTCTTACGGTTA
AGAGAAGGAGTAACGACACA

Downstream 100 bases:

>100_bases
TCAGTCTGAACCCCCCGTATTACGGCGGTTTGCTGCTGTAAACACAGGGCGGATACATTGACGGCGCCGAGCTGCGCCGT
TAATGTGTCCGCCTTCTTTT

Product: protein disulfide-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKKGLLFVLLGLMTACGASSEGNKGNAEIDGDQAKAAFENAFDGVEVSDVRAAPMAGMLELEVNGGETVYMSENGRFVMV
GKLLELKDGEVINPAEQRLEKVRADGIKTLNKDDMISYVAPEETAEVYVFTDITCGYCRKLHRHIEEYMDSGVTVHYLAF
PRGGPTTKAAAAMRHIWCAEDRLQALTDAKLNEKVSDAELGECAKPVDEQYPLGLKFGVRGTPAIYTSEGKQLGGYLPPK
DLLKRLN

Sequences:

>Translated_247_residues
MKKGLLFVLLGLMTACGASSEGNKGNAEIDGDQAKAAFENAFDGVEVSDVRAAPMAGMLELEVNGGETVYMSENGRFVMV
GKLLELKDGEVINPAEQRLEKVRADGIKTLNKDDMISYVAPEETAEVYVFTDITCGYCRKLHRHIEEYMDSGVTVHYLAF
PRGGPTTKAAAAMRHIWCAEDRLQALTDAKLNEKVSDAELGECAKPVDEQYPLGLKFGVRGTPAIYTSEGKQLGGYLPPK
DLLKRLN
>Mature_247_residues
MKKGLLFVLLGLMTACGASSEGNKGNAEIDGDQAKAAFENAFDGVEVSDVRAAPMAGMLELEVNGGETVYMSENGRFVMV
GKLLELKDGEVINPAEQRLEKVRADGIKTLNKDDMISYVAPEETAEVYVFTDITCGYCRKLHRHIEEYMDSGVTVHYLAF
PRGGPTTKAAAAMRHIWCAEDRLQALTDAKLNEKVSDAELGECAKPVDEQYPLGLKFGVRGTPAIYTSEGKQLGGYLPPK
DLLKRLN

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=249, Percent_Identity=35.7429718875502, Blast_Score=150, Evalue=5e-38,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26940; Mature: 26940

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLLFVLLGLMTACGASSEGNKGNAEIDGDQAKAAFENAFDGVEVSDVRAAPMAGMLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHCCCCEECCCCCCCCCCEEE
LEVNGGETVYMSENGRFVMVGKLLELKDGEVINPAEQRLEKVRADGIKTLNKDDMISYVA
EEECCCCEEEECCCCCEEEEEEEEECCCCCEECHHHHHHHHHHHHCCCCCCCCCCEEEEC
PEETAEVYVFTDITCGYCRKLHRHIEEYMDSGVTVHYLAFPRGGPTTKAAAAMRHIWCAE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
DRLQALTDAKLNEKVSDAELGECAKPVDEQYPLGLKFGVRGTPAIYTSEGKQLGGYLPPK
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHH
DLLKRLN
HHHHHCC
>Mature Secondary Structure
MKKGLLFVLLGLMTACGASSEGNKGNAEIDGDQAKAAFENAFDGVEVSDVRAAPMAGMLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHCCCCEECCCCCCCCCCEEE
LEVNGGETVYMSENGRFVMVGKLLELKDGEVINPAEQRLEKVRADGIKTLNKDDMISYVA
EEECCCCEEEECCCCCEEEEEEEEECCCCCEECHHHHHHHHHHHHCCCCCCCCCCEEEEC
PEETAEVYVFTDITCGYCRKLHRHIEEYMDSGVTVHYLAFPRGGPTTKAAAAMRHIWCAE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
DRLQALTDAKLNEKVSDAELGECAKPVDEQYPLGLKFGVRGTPAIYTSEGKQLGGYLPPK
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHH
DLLKRLN
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]