Click here to switch to the map view.

The map label for this gene is rstB [H]

Identifier: 110833574

GI number: 110833574

Start: 799937

End: 801562

Strand: Direct

Name: rstB [H]

Synonym: ABO_0713

Alternate gene names: 110833574

Gene position: 799937-801562 (Clockwise)

Preceding gene: 110833573

Following gene: 110833575

Centisome position: 25.64

GC content: 54.18

Gene sequence:

>1626_bases
TTGAATAGTATTTTCCTGAGGCTCTACGGGGGCTTGTTGCTGGCGCTGTGTTTGATCGGCGCCATCACCTATGGTGCGGT
GGAGCTGGTGAACAGTTACCGATCCGACCTGTACCGTGAAAAGATGGCCCGGGGCACCTTCTTTCTGATGGCGGAAGGCT
ACCAGCATTATGAGGTTGGCGACCGCGATCGCTGGAGTCAGGTGCTTAGCAAGCTGTTCAGTGCCGAGATCGCGCTGCTC
TCCAGTGATGATCTGGCGCTGGGGTATCGGGAACGTTTGCACCTTGAAGACGGCCTTGTGGTGATGCGTCTGAATGACGA
TGCGGGCTACGCCGATGTCTTGTTTCAGCTTCCTGGCGAAGATGTCTATATCAACACGCGGATGACCAAGGTGTCTGAAC
AACAGGCGCGGGCTACGGCTGTGTTGATCCTTCATTATTTGTCCCATTTCCAAGAATCAGAGTGGGATCAGGCGTTGACT
ACTTTGCAGCGTCAGTTCGGTTACCCTCTGACGTTGCTGCAGCGCGATGATGTCTCTCTGGATGATGAGCAAGAACAGCG
ACTCGGGCGCCGTGAGGTGGTTATTGCTCTTGACGACAGTACTCGCAATGATTCCAGTATCCGGATTTATGCGCCGGTGG
CACAAACCGATAAATTGTTGGTGCTTGGCCCGCTGAGCTTGTTTGACCGGTTTCCTATTGAGTTGCTGTTGATTGCTGGT
ATTACCAGCTTGTTGGCGGTGGCGCTGGCCACTTATCTACAGGTGAGCCCCCTGCAGCGGCGACTCAAGAGGCTTGATAA
GGCGGTGAGTCAGTTGGGCAGTGGGGACCTGGGAGCCTATGCCAATATCGAAGGCAGTGATGCCATTGGGCAGGTGGCAG
CAACCTTTAATGGTATGACGGCACATATTCGTCGTTTGATTGAGTCACAGCGAGAGATGACTCGCGCAGTGAGCCATGAA
TTACGCACCCCGGTGGCGCGGTTGCGTTTTGGGCTGGAGATGCTTGCCGATATTGAGTCGGCGGAGCGTCGCCGTGAAAA
GCTCAATGCTATGGATCAAGATATCGAACAGCTGGATCAGCTGATTGACGAAATCCTTACCTATGCTCGCTTGGAGCAAG
GCACTCCTAATATTGAATTCAAACCGGTGGTGATTGGCGAATTGTGCGAACAGCTGCGCGATGAGTTGGAAACCATTCGT
GATGAAACGGTCATCACCGTGAACAACGCTTGCCCGACCCTCAAAGTGGAAGCGGAGGAACGCTATCTGCATCGGGTGCT
TCAGAACTTGGTGACCAATGCCTTGCGCTACGCTAAATCCCATATTGTTATGCGGGTTGAGGAGAGTGATGATCTGGTGT
TCATTCATGTGGATGACGACGGCCCGGGGATTCCAGAGCACGAACGCGAGCGGGTGTTTAAACCCTTTGCCCGTTTGGAT
AAGAGCCGCCACCGGGCCAGCGGTGGGTACGGTTTGGGTTTGTCCATTGTGAAACGTATTGTGGATTGGCACGGAGGCGG
GATTTGCGTGGATGAAAGCCCGCAAGGTGGTGCCCGCTTTACCGTGACCTTGCCCAAGGATCAGCAGGGCCAGCATGTGC
TAGGGCGGGTGAACGAACTTCATTGA

Upstream 100 bases:

>100_bases
CAAAACGGTACGCTCCAAGGGGTATCTGTTCGTCAAGGAAATCGGCGCAATATAACGGCTGAGTTGGTCGTTGCGGCGCA
GGGATGACGCTGGGTGATGT

Downstream 100 bases:

>100_bases
ATAGGGAAAGCTTAAATGTTCCTCTATTTAGGCCTTTGCACAAAGCCGCTGGTAGCCGATAAGGTCTATTGGGTTGGCCG
TTATTGTGCAATGTGTCATC

Product: sensor histidine kinase rstB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNSIFLRLYGGLLLALCLIGAITYGAVELVNSYRSDLYREKMARGTFFLMAEGYQHYEVGDRDRWSQVLSKLFSAEIALL
SSDDLALGYRERLHLEDGLVVMRLNDDAGYADVLFQLPGEDVYINTRMTKVSEQQARATAVLILHYLSHFQESEWDQALT
TLQRQFGYPLTLLQRDDVSLDDEQEQRLGRREVVIALDDSTRNDSSIRIYAPVAQTDKLLVLGPLSLFDRFPIELLLIAG
ITSLLAVALATYLQVSPLQRRLKRLDKAVSQLGSGDLGAYANIEGSDAIGQVAATFNGMTAHIRRLIESQREMTRAVSHE
LRTPVARLRFGLEMLADIESAERRREKLNAMDQDIEQLDQLIDEILTYARLEQGTPNIEFKPVVIGELCEQLRDELETIR
DETVITVNNACPTLKVEAEERYLHRVLQNLVTNALRYAKSHIVMRVEESDDLVFIHVDDDGPGIPEHERERVFKPFARLD
KSRHRASGGYGLGLSIVKRIVDWHGGGICVDESPQGGARFTVTLPKDQQGQHVLGRVNELH

Sequences:

>Translated_541_residues
MNSIFLRLYGGLLLALCLIGAITYGAVELVNSYRSDLYREKMARGTFFLMAEGYQHYEVGDRDRWSQVLSKLFSAEIALL
SSDDLALGYRERLHLEDGLVVMRLNDDAGYADVLFQLPGEDVYINTRMTKVSEQQARATAVLILHYLSHFQESEWDQALT
TLQRQFGYPLTLLQRDDVSLDDEQEQRLGRREVVIALDDSTRNDSSIRIYAPVAQTDKLLVLGPLSLFDRFPIELLLIAG
ITSLLAVALATYLQVSPLQRRLKRLDKAVSQLGSGDLGAYANIEGSDAIGQVAATFNGMTAHIRRLIESQREMTRAVSHE
LRTPVARLRFGLEMLADIESAERRREKLNAMDQDIEQLDQLIDEILTYARLEQGTPNIEFKPVVIGELCEQLRDELETIR
DETVITVNNACPTLKVEAEERYLHRVLQNLVTNALRYAKSHIVMRVEESDDLVFIHVDDDGPGIPEHERERVFKPFARLD
KSRHRASGGYGLGLSIVKRIVDWHGGGICVDESPQGGARFTVTLPKDQQGQHVLGRVNELH
>Mature_541_residues
MNSIFLRLYGGLLLALCLIGAITYGAVELVNSYRSDLYREKMARGTFFLMAEGYQHYEVGDRDRWSQVLSKLFSAEIALL
SSDDLALGYRERLHLEDGLVVMRLNDDAGYADVLFQLPGEDVYINTRMTKVSEQQARATAVLILHYLSHFQESEWDQALT
TLQRQFGYPLTLLQRDDVSLDDEQEQRLGRREVVIALDDSTRNDSSIRIYAPVAQTDKLLVLGPLSLFDRFPIELLLIAG
ITSLLAVALATYLQVSPLQRRLKRLDKAVSQLGSGDLGAYANIEGSDAIGQVAATFNGMTAHIRRLIESQREMTRAVSHE
LRTPVARLRFGLEMLADIESAERRREKLNAMDQDIEQLDQLIDEILTYARLEQGTPNIEFKPVVIGELCEQLRDELETIR
DETVITVNNACPTLKVEAEERYLHRVLQNLVTNALRYAKSHIVMRVEESDDLVFIHVDDDGPGIPEHERERVFKPFARLD
KSRHRASGGYGLGLSIVKRIVDWHGGGICVDESPQGGARFTVTLPKDQQGQHVLGRVNELH

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=375, Percent_Identity=31.7333333333333, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=31.8518518518519, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789808, Length=328, Percent_Identity=28.3536585365854, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1788393, Length=267, Percent_Identity=28.8389513108614, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=29.0969899665552, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=27.6094276094276, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=30.9417040358744, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=27.0833333333333, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082128, Length=300, Percent_Identity=29.3333333333333, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=31.7391304347826, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788279, Length=307, Percent_Identity=25.4071661237785, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=29.004329004329, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1787374, Length=364, Percent_Identity=26.0989010989011, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=28.9592760180996, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=283, Percent_Identity=23.321554770318, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI48994928, Length=216, Percent_Identity=25, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=26.2931034482759, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=302, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=205, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61116; Mature: 61116

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIFLRLYGGLLLALCLIGAITYGAVELVNSYRSDLYREKMARGTFFLMAEGYQHYEVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
DRDRWSQVLSKLFSAEIALLSSDDLALGYRERLHLEDGLVVMRLNDDAGYADVLFQLPGE
CHHHHHHHHHHHHHHHEEEECCCCCEECHHHHEEECCCEEEEEECCCCCHHHHHEECCCC
DVYINTRMTKVSEQQARATAVLILHYLSHFQESEWDQALTTLQRQFGYPLTLLQRDDVSL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCC
DDEQEQRLGRREVVIALDDSTRNDSSIRIYAPVAQTDKLLVLGPLSLFDRFPIELLLIAG
CCHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEECHHHHHHCCHHHHHHHH
ITSLLAVALATYLQVSPLQRRLKRLDKAVSQLGSGDLGAYANIEGSDAIGQVAATFNGMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHCHHH
AHIRRLIESQREMTRAVSHELRTPVARLRFGLEMLADIESAERRREKLNAMDQDIEQLDQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDEILTYARLEQGTPNIEFKPVVIGELCEQLRDELETIRDETVITVNNACPTLKVEAEE
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECHHH
RYLHRVLQNLVTNALRYAKSHIVMRVEESDDLVFIHVDDDGPGIPEHERERVFKPFARLD
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
KSRHRASGGYGLGLSIVKRIVDWHGGGICVDESPQGGARFTVTLPKDQQGQHVLGRVNEL
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCC
H
C
>Mature Secondary Structure
MNSIFLRLYGGLLLALCLIGAITYGAVELVNSYRSDLYREKMARGTFFLMAEGYQHYEVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
DRDRWSQVLSKLFSAEIALLSSDDLALGYRERLHLEDGLVVMRLNDDAGYADVLFQLPGE
CHHHHHHHHHHHHHHHEEEECCCCCEECHHHHEEECCCEEEEEECCCCCHHHHHEECCCC
DVYINTRMTKVSEQQARATAVLILHYLSHFQESEWDQALTTLQRQFGYPLTLLQRDDVSL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCC
DDEQEQRLGRREVVIALDDSTRNDSSIRIYAPVAQTDKLLVLGPLSLFDRFPIELLLIAG
CCHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEECHHHHHHCCHHHHHHHH
ITSLLAVALATYLQVSPLQRRLKRLDKAVSQLGSGDLGAYANIEGSDAIGQVAATFNGMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHCHHH
AHIRRLIESQREMTRAVSHELRTPVARLRFGLEMLADIESAERRREKLNAMDQDIEQLDQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDEILTYARLEQGTPNIEFKPVVIGELCEQLRDELETIRDETVITVNNACPTLKVEAEE
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECHHH
RYLHRVLQNLVTNALRYAKSHIVMRVEESDDLVFIHVDDDGPGIPEHERERVFKPFARLD
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
KSRHRASGGYGLGLSIVKRIVDWHGGGICVDESPQGGARFTVTLPKDQQGQHVLGRVNEL
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]