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The map label for this gene is siaT [H]

Identifier: 110680919

GI number: 110680919

Start: 3654115

End: 3655470

Strand: Direct

Name: siaT [H]

Synonym: RD1_3772

Alternate gene names: 110680919

Gene position: 3654115-3655470 (Clockwise)

Preceding gene: 110680918

Following gene: 110680920

Centisome position: 88.41

GC content: 59.81

Gene sequence:

>1356_bases
ATGGGCATTGAAATCGGAATTGAGCTTTTAACGCTCATCATGTTCGGCAGCCTGCTGGCGCTTTTGATGGCGGGTTTGCC
ACTGGCCTTTGTCACGGGCGGTCTGGCGTGCGTGTTCCTCTTTATCCTTGGGGACGCGCAGGCGCTCAACATCGTGCCAA
GCCGCATCTTTCCGCTGATGACGAACTACCAGTTGTCGGCCATCCCGCTCTTTATCTTCATGGCCGCCATGCTTGAGCGG
GCGGGGATCATCAACGACATGTTCGATGTGATCTACAAGGTGCTGGGCGGCGTGCGCGGGGGGTTGGCTGCGGCAACGAT
CATCGCCTCCACCGTGCTGGCGGCCATGGTTGGTGTGATTGGTGCCGCCGTTGTGACCATGGGCATCATCGCCCTGCCCG
CCATGCTGAAACGCGGCTATGATCCCAAGATCGCCATGGGCTCGATCATGGCCGGGGGCACGCTGGGCATCCTGATCCCC
CCGTCCATCCTCGCGATCATCTACGCGGTTGTGGCGGAGCAATCGGTCGGGGAACTGTTCATCGGTGCGGTGATCCCCGG
TCTGATGCTGTCGGGCATGTACATCATGTACGTTCTGGCACGCAGCGCCATCAACCCGACGCTCGGCCCGCCTATTCCAA
TGGAGGAGCGGGTATCCACGCGGGAAAAGATCCGTCTGGTCGGTAAAATGTCCGCGCCGATCGCCCTGATCGCCGTGGTG
CTGGGGGTGATCTTCTCCGGCGTCGCCACCCCGGTTGAGGCGGCAGGCATCGGGACCTTCGGCGCGTTTATCGTCGCGGC
CATCCACCGCAAGCTCACCTGGCCAACGGTGCGCGAGGCCTGCCTGACCACGCTGAAAGCCAGCGCGATGGTCATCTGGA
TCATGTTCGGTGCAACCATTTTCGTGGGTCTCTACGTGCTTGAAGGTGGCCAGCAATTCGTACAGGACAGCCTTGCCGCC
ACAGGTTTTGGTCCATGGGGCATCCTGATCATCATGATGATCGTGCTGGTCGTTCTGGGCATGTTCCTTGACTGGGTCGG
CATCCTGCTGTTGTGCGTGCCGATCTTTGTGCCGATCATCAAGGCCATGGGGCCGGAGCCTTTCGGCATGACCGATCCCA
ACGATCTGGTGCTGTGGTTTGGGGTGCTTTATCTGGTCAACATGCAGATGTCGTTCCTGTCACCGCCCTTTGGCTATGCG
CTGTTCTACCTGCGCGGGGTGGCCCCGCCCGAAATTCCGATGACGGATATTTTCAAGGCAGCACTTCCCTTCCTTGCGCT
GCAAATCGTGGCCCTCGTGATCTGCATGTTCTTTCCGCAGGTCATCACCTGGCTACCCAATCTGGTCTACGGATAA

Upstream 100 bases:

>100_bases
GATGAAATGGGTCATGGTGATTGGCGGTCTGCTTTTGGTGCTGCAAGGCATCTCGAAGCTGGCAAAAGACGTGCGCGCTG
TCGCAAGAGGGGCATAGACC

Downstream 100 bases:

>100_bases
CGGTGCAGACAAAACGGCGGCCCCACGGGTCGCCGTTTTCATCTGAGGCGGCAACAGGGCATAAAGCCCCCTATTCAAAG
TGCGCAATATTTGACAACCT

Product: TRAP dicarboxylate transporter, DctM subunit, putative

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MGIEIGIELLTLIMFGSLLALLMAGLPLAFVTGGLACVFLFILGDAQALNIVPSRIFPLMTNYQLSAIPLFIFMAAMLER
AGIINDMFDVIYKVLGGVRGGLAAATIIASTVLAAMVGVIGAAVVTMGIIALPAMLKRGYDPKIAMGSIMAGGTLGILIP
PSILAIIYAVVAEQSVGELFIGAVIPGLMLSGMYIMYVLARSAINPTLGPPIPMEERVSTREKIRLVGKMSAPIALIAVV
LGVIFSGVATPVEAAGIGTFGAFIVAAIHRKLTWPTVREACLTTLKASAMVIWIMFGATIFVGLYVLEGGQQFVQDSLAA
TGFGPWGILIIMMIVLVVLGMFLDWVGILLLCVPIFVPIIKAMGPEPFGMTDPNDLVLWFGVLYLVNMQMSFLSPPFGYA
LFYLRGVAPPEIPMTDIFKAALPFLALQIVALVICMFFPQVITWLPNLVYG

Sequences:

>Translated_451_residues
MGIEIGIELLTLIMFGSLLALLMAGLPLAFVTGGLACVFLFILGDAQALNIVPSRIFPLMTNYQLSAIPLFIFMAAMLER
AGIINDMFDVIYKVLGGVRGGLAAATIIASTVLAAMVGVIGAAVVTMGIIALPAMLKRGYDPKIAMGSIMAGGTLGILIP
PSILAIIYAVVAEQSVGELFIGAVIPGLMLSGMYIMYVLARSAINPTLGPPIPMEERVSTREKIRLVGKMSAPIALIAVV
LGVIFSGVATPVEAAGIGTFGAFIVAAIHRKLTWPTVREACLTTLKASAMVIWIMFGATIFVGLYVLEGGQQFVQDSLAA
TGFGPWGILIIMMIVLVVLGMFLDWVGILLLCVPIFVPIIKAMGPEPFGMTDPNDLVLWFGVLYLVNMQMSFLSPPFGYA
LFYLRGVAPPEIPMTDIFKAALPFLALQIVALVICMFFPQVITWLPNLVYG
>Mature_450_residues
GIEIGIELLTLIMFGSLLALLMAGLPLAFVTGGLACVFLFILGDAQALNIVPSRIFPLMTNYQLSAIPLFIFMAAMLERA
GIINDMFDVIYKVLGGVRGGLAAATIIASTVLAAMVGVIGAAVVTMGIIALPAMLKRGYDPKIAMGSIMAGGTLGILIPP
SILAIIYAVVAEQSVGELFIGAVIPGLMLSGMYIMYVLARSAINPTLGPPIPMEERVSTREKIRLVGKMSAPIALIAVVL
GVIFSGVATPVEAAGIGTFGAFIVAAIHRKLTWPTVREACLTTLKASAMVIWIMFGATIFVGLYVLEGGQQFVQDSLAAT
GFGPWGILIIMMIVLVVLGMFLDWVGILLLCVPIFVPIIKAMGPEPFGMTDPNDLVLWFGVLYLVNMQMSFLSPPFGYAL
FYLRGVAPPEIPMTDIFKAALPFLALQIVALVICMFFPQVITWLPNLVYG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=435, Percent_Identity=25.0574712643678, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 47996; Mature: 47865

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEIGIELLTLIMFGSLLALLMAGLPLAFVTGGLACVFLFILGDAQALNIVPSRIFPLM
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TNYQLSAIPLFIFMAAMLERAGIINDMFDVIYKVLGGVRGGLAAATIIASTVLAAMVGVI
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GAAVVTMGIIALPAMLKRGYDPKIAMGSIMAGGTLGILIPPSILAIIYAVVAEQSVGELF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
IGAVIPGLMLSGMYIMYVLARSAINPTLGPPIPMEERVSTREKIRLVGKMSAPIALIAVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGVIFSGVATPVEAAGIGTFGAFIVAAIHRKLTWPTVREACLTTLKASAMVIWIMFGATI
HHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGLYVLEGGQQFVQDSLAATGFGPWGILIIMMIVLVVLGMFLDWVGILLLCVPIFVPII
HHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAMGPEPFGMTDPNDLVLWFGVLYLVNMQMSFLSPPFGYALFYLRGVAPPEIPMTDIFKA
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHH
ALPFLALQIVALVICMFFPQVITWLPNLVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GIEIGIELLTLIMFGSLLALLMAGLPLAFVTGGLACVFLFILGDAQALNIVPSRIFPLM
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]