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The map label for this gene is 110680743

Identifier: 110680743

GI number: 110680743

Start: 3447673

End: 3449628

Strand: Direct

Name: 110680743

Synonym: RD1_3585

Alternate gene names: NA

Gene position: 3447673-3449628 (Clockwise)

Preceding gene: 110680742

Following gene: 110680745

Centisome position: 83.42

GC content: 59.15

Gene sequence:

>1956_bases
ATGAGTGATTCAAAAGCCCTAGACCCCGTCACGTTTGAAGTTCTCAAGAACTCATTCATCACCTCGGTCGACCAGATGGC
CGAGCAGATGTTGCGTACCTGCTATTCCTTCGTGATCTACAATCGCGATTTTTCCAACGCGTTGCATGACGCCGAAGGCA
ACTCGGTCGCGCAAGGCAACGATGATATCGCCGTGCATGTGGGCACGCTGCATTTCACTTGTAAGGACGTCATTCGCGTC
TTCAAGGGCGATATGATGCCGGGGGATGTCTACGCGATCAATGACCCCTACGCGGGCGGTACGCATTTCAGCGATGTCCG
TTTGGTGCGGCCGATTTTTGACGAAGACGAACTGATCGGCTTCTCGCAGTCCAACGGCCATTGGTCCGATTTGGGGGGGT
CTGTTCCCGGCTCGTTCGACGTGACGGCCAGGGATATGTTCCGTGAAGCGGTGCGTATTACCCCGGTCCGCCTGTTCCGC
GCGGGCGATTTTTGCTCGGACGTGGCGAACCTGATTGCCAACAACACCCGCGACCCTGCGTCGATCATCGGTGATATCCA
CTCGCAGGCCCAGGCGACGCAGGTGGCAGAGCGCGAAATCCTGCGGCTGGTGCGCAAATATGGCCGCGCGCAAGTGACCC
AGGGTATGAACGAAGTGCAGGATTACGTCGAACGCGCTGTGCGCCAGCGGATCGCTGCGCTGCCGGATGGCACATGGGAG
TCGGTGGATTACATTGACCGGGACCCTGCCGCGGGCGAGGGAATGATCCCGATCCACATCAAGATGACGATCAAGGGCGA
TCAGATCTTCTATGATTTCTCGGGCAGCCATCCGACAATCGGGTCGATGTACAACTCCGCACCGGGCGCGACCTTCTCGG
CGGTGGTGGCTGGGATGAAAACCTTCTTCCCCGACCTGCCACTCAACAGCGGTTTCTATCGGATGATCTCTGTCGAGGCA
CCGGAGAATTCTGTCGTCAGCGCCCAGTGGCCTGTCGCGGTCACGGGCTTCCTGATGCCGTTTGAGAAGATCATGAATTC
GGTCTTTGAAATGTGGTCCCAGATCATGCCCGAACGTGCCATCGCCTGCGCATTCAATCTGGAATACCTGCTGGCAGGCG
GCACCGACAAGCGCCGCGACGAAGATTCCACTTTCATGTTCTATGAATGGCTTCCCGGTGGATGGGGAGGTCGCCGTGGC
AAGGATGGCAGCGATGTTACAACGGCATGTTTCGGCACCGGCCTGATGTCTCAGCCCAATGAAGGCAATGAACGGGTCAA
TCCAACCCGCACGCTGGAATTCCAGATCAAACAAGACAGCGCGGGTCCGGGCAAGTGGCGCGGTGGGGCTGGGGTGCAGA
AAACATCTCTGCTGCTGGAAAGCGAAAAATCGGTCATGTCCTATGTCTGTGACCGAGAGCGTGCCGTTGTCTGGGGCGTC
GAGGGGGGGCTGCCGTCCATGCCCCATGGTCTGACGATCAAACGGGCTGGCTCTGACACGTCGGAATGGCTTGGCTCCGT
CTTCTCGGACTTTCCCATGTATTCGGGGGATGAGTTCGCGCGGCCCACGGCGGGCGGCGGCGGCTTTGGGGATCCGCTGG
AACGCGCCCCCGAAATGGTGCTCGAAGATGTCATCGACGAATATGTCTCTGTGGACCGGGCGGCCAAGGACTACGGAGTC
GTCATCAAGGAGATAGACCGCGATCTGCTGTCTTATGAGATTGACGAAGAAGCCACGGCCGAGCTGCGCGCCCATATCCG
CGCAAACCGCAAGGACTGGGCCCGCTCCGATCCGGCAGAGGTGTCAAAGCTCTACAAGAGCGGTGAGATCGACGCGATGG
ACGCCGTCCGACGCTATGCCGTGATCCTCGATTGGGAGACGGGCGAGCCTCTGCCCAAGACCATCGAGCAATTCCGCGAG
AGCTTTGAACGCCGCAGCCTCGCGCATTGGTCGTGA

Upstream 100 bases:

>100_bases
ATTGTCGAGCAGTTTGACTCAACCACCGTGATTCCGCCGAACACGACTGCTGAAGTCGACAAATACATGAACATTCTCAT
CCGAGTTCAGGAGTAAAATC

Downstream 100 bases:

>100_bases
TCTCATAGATCGGCTTGCGGCTGTCCGTTCAGGCTGGCCGCAAGCCACGTAGTTGCATCTGCGCGCCGCAGCATCGGCGA
CGCACCAACCACGAAGGATA

Product: hydantoin utilization protein B, putative

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MSDSKALDPVTFEVLKNSFITSVDQMAEQMLRTCYSFVIYNRDFSNALHDAEGNSVAQGNDDIAVHVGTLHFTCKDVIRV
FKGDMMPGDVYAINDPYAGGTHFSDVRLVRPIFDEDELIGFSQSNGHWSDLGGSVPGSFDVTARDMFREAVRITPVRLFR
AGDFCSDVANLIANNTRDPASIIGDIHSQAQATQVAEREILRLVRKYGRAQVTQGMNEVQDYVERAVRQRIAALPDGTWE
SVDYIDRDPAAGEGMIPIHIKMTIKGDQIFYDFSGSHPTIGSMYNSAPGATFSAVVAGMKTFFPDLPLNSGFYRMISVEA
PENSVVSAQWPVAVTGFLMPFEKIMNSVFEMWSQIMPERAIACAFNLEYLLAGGTDKRRDEDSTFMFYEWLPGGWGGRRG
KDGSDVTTACFGTGLMSQPNEGNERVNPTRTLEFQIKQDSAGPGKWRGGAGVQKTSLLLESEKSVMSYVCDRERAVVWGV
EGGLPSMPHGLTIKRAGSDTSEWLGSVFSDFPMYSGDEFARPTAGGGGFGDPLERAPEMVLEDVIDEYVSVDRAAKDYGV
VIKEIDRDLLSYEIDEEATAELRAHIRANRKDWARSDPAEVSKLYKSGEIDAMDAVRRYAVILDWETGEPLPKTIEQFRE
SFERRSLAHWS

Sequences:

>Translated_651_residues
MSDSKALDPVTFEVLKNSFITSVDQMAEQMLRTCYSFVIYNRDFSNALHDAEGNSVAQGNDDIAVHVGTLHFTCKDVIRV
FKGDMMPGDVYAINDPYAGGTHFSDVRLVRPIFDEDELIGFSQSNGHWSDLGGSVPGSFDVTARDMFREAVRITPVRLFR
AGDFCSDVANLIANNTRDPASIIGDIHSQAQATQVAEREILRLVRKYGRAQVTQGMNEVQDYVERAVRQRIAALPDGTWE
SVDYIDRDPAAGEGMIPIHIKMTIKGDQIFYDFSGSHPTIGSMYNSAPGATFSAVVAGMKTFFPDLPLNSGFYRMISVEA
PENSVVSAQWPVAVTGFLMPFEKIMNSVFEMWSQIMPERAIACAFNLEYLLAGGTDKRRDEDSTFMFYEWLPGGWGGRRG
KDGSDVTTACFGTGLMSQPNEGNERVNPTRTLEFQIKQDSAGPGKWRGGAGVQKTSLLLESEKSVMSYVCDRERAVVWGV
EGGLPSMPHGLTIKRAGSDTSEWLGSVFSDFPMYSGDEFARPTAGGGGFGDPLERAPEMVLEDVIDEYVSVDRAAKDYGV
VIKEIDRDLLSYEIDEEATAELRAHIRANRKDWARSDPAEVSKLYKSGEIDAMDAVRRYAVILDWETGEPLPKTIEQFRE
SFERRSLAHWS
>Mature_650_residues
SDSKALDPVTFEVLKNSFITSVDQMAEQMLRTCYSFVIYNRDFSNALHDAEGNSVAQGNDDIAVHVGTLHFTCKDVIRVF
KGDMMPGDVYAINDPYAGGTHFSDVRLVRPIFDEDELIGFSQSNGHWSDLGGSVPGSFDVTARDMFREAVRITPVRLFRA
GDFCSDVANLIANNTRDPASIIGDIHSQAQATQVAEREILRLVRKYGRAQVTQGMNEVQDYVERAVRQRIAALPDGTWES
VDYIDRDPAAGEGMIPIHIKMTIKGDQIFYDFSGSHPTIGSMYNSAPGATFSAVVAGMKTFFPDLPLNSGFYRMISVEAP
ENSVVSAQWPVAVTGFLMPFEKIMNSVFEMWSQIMPERAIACAFNLEYLLAGGTDKRRDEDSTFMFYEWLPGGWGGRRGK
DGSDVTTACFGTGLMSQPNEGNERVNPTRTLEFQIKQDSAGPGKWRGGAGVQKTSLLLESEKSVMSYVCDRERAVVWGVE
GGLPSMPHGLTIKRAGSDTSEWLGSVFSDFPMYSGDEFARPTAGGGGFGDPLERAPEMVLEDVIDEYVSVDRAAKDYGVV
IKEIDRDLLSYEIDEEATAELRAHIRANRKDWARSDPAEVSKLYKSGEIDAMDAVRRYAVILDWETGEPLPKTIEQFRES
FERRSLAHWS

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=551, Percent_Identity=26.3157894736842, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI133901900, Length=557, Percent_Identity=27.1095152603232, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI133901902, Length=519, Percent_Identity=26.5895953757225, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322634, Length=555, Percent_Identity=24.3243243243243, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI45550492, Length=549, Percent_Identity=27.3224043715847, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 72252; Mature: 72121

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSKALDPVTFEVLKNSFITSVDQMAEQMLRTCYSFVIYNRDFSNALHDAEGNSVAQGN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
DDIAVHVGTLHFTCKDVIRVFKGDMMPGDVYAINDPYAGGTHFSDVRLVRPIFDEDELIG
CCEEEEEEEEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHEECCCCCCCCEEE
FSQSNGHWSDLGGSVPGSFDVTARDMFREAVRITPVRLFRAGDFCSDVANLIANNTRDPA
ECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHCCCCCHH
SIIGDIHSQAQATQVAEREILRLVRKYGRAQVTQGMNEVQDYVERAVRQRIAALPDGTWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SVDYIDRDPAAGEGMIPIHIKMTIKGDQIFYDFSGSHPTIGSMYNSAPGATFSAVVAGMK
CCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHH
TFFPDLPLNSGFYRMISVEAPENSVVSAQWPVAVTGFLMPFEKIMNSVFEMWSQIMPERA
HHCCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IACAFNLEYLLAGGTDKRRDEDSTFMFYEWLPGGWGGRRGKDGSDVTTACFGTGLMSQPN
HHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
EGNERVNPTRTLEFQIKQDSAGPGKWRGGAGVQKTSLLLESEKSVMSYVCDRERAVVWGV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
EGGLPSMPHGLTIKRAGSDTSEWLGSVFSDFPMYSGDEFARPTAGGGGFGDPLERAPEMV
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LEDVIDEYVSVDRAAKDYGVVIKEIDRDLLSYEIDEEATAELRAHIRANRKDWARSDPAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCHHH
VSKLYKSGEIDAMDAVRRYAVILDWETGEPLPKTIEQFRESFERRSLAHWS
HHHHHHCCCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDSKALDPVTFEVLKNSFITSVDQMAEQMLRTCYSFVIYNRDFSNALHDAEGNSVAQGN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
DDIAVHVGTLHFTCKDVIRVFKGDMMPGDVYAINDPYAGGTHFSDVRLVRPIFDEDELIG
CCEEEEEEEEEHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHEECCCCCCCCEEE
FSQSNGHWSDLGGSVPGSFDVTARDMFREAVRITPVRLFRAGDFCSDVANLIANNTRDPA
ECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHCCCCCHH
SIIGDIHSQAQATQVAEREILRLVRKYGRAQVTQGMNEVQDYVERAVRQRIAALPDGTWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SVDYIDRDPAAGEGMIPIHIKMTIKGDQIFYDFSGSHPTIGSMYNSAPGATFSAVVAGMK
CCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHH
TFFPDLPLNSGFYRMISVEAPENSVVSAQWPVAVTGFLMPFEKIMNSVFEMWSQIMPERA
HHCCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IACAFNLEYLLAGGTDKRRDEDSTFMFYEWLPGGWGGRRGKDGSDVTTACFGTGLMSQPN
HHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
EGNERVNPTRTLEFQIKQDSAGPGKWRGGAGVQKTSLLLESEKSVMSYVCDRERAVVWGV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
EGGLPSMPHGLTIKRAGSDTSEWLGSVFSDFPMYSGDEFARPTAGGGGFGDPLERAPEMV
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LEDVIDEYVSVDRAAKDYGVVIKEIDRDLLSYEIDEEATAELRAHIRANRKDWARSDPAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCHHH
VSKLYKSGEIDAMDAVRRYAVILDWETGEPLPKTIEQFRESFERRSLAHWS
HHHHHHCCCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]