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The map label for this gene is hyuA

Identifier: 110680742

GI number: 110680742

Start: 3445641

End: 3447668

Strand: Direct

Name: hyuA

Synonym: RD1_3584

Alternate gene names: NA

Gene position: 3445641-3447668 (Clockwise)

Preceding gene: 110680741

Following gene: 110680743

Centisome position: 83.37

GC content: 58.38

Gene sequence:

>2028_bases
ATGAAAAATACCAGAGTAGCTGTGGATGTGGGCGGAACGTTTACCGACGTTTGCATCATGGATGAAACCACAGGTGCGAT
CCGCATCGAAAAGACGTCATCCACCCCGGATGATCCAATGGTCGCCATCCTCAACGGGATTGATCAGGGCGGCATCGACC
TCAGTGAGGTGTCGATGTTCTCGCATGGTACAACCGTTGCCACCAATGCGCTGATCACACGAAATCTGGCGCGCTCCGCA
ATGATTTGCACCGAAGGTTTTCGCGATGTGGTCGAGATACGCCGCGCCAACAAGGAGGACCTTTGGGACACATACAAGGA
CGTCGCCAAACCCTACATCCCGCGCCGTGATCGACTGACCGTAAGGGAATGTGTCGATGCGAATGGCACCGTGCTGGAAA
AGCTGGACGAGGAAGAAGCACTGCGCATCGCGAACATTCTGAAAAAGCGCAAAGTCGCTTCGGTCGCGGTCTGCTTCATG
AACTCCTACACCAACGGCGCGAATGAAGAGCGGATGCGTGACATTCTGCTCAGCGTGATGCCGGATGTGCCTGTTTCCAT
CTCTTCGCAGGTATTGCCGGAGATCTTTGAACACGAGCGGTTTTCCACCACGATGGCAAATGCGGTCGTCTCGCCTTCGG
TCGTCGATTATGTGGAACGGCTTGAGGGCAAGCTGTCTGACGGAGGATATGAGCGTGACCTGCTGCTGCTGCACACAGGC
GGCGGCGTGATGACGCCTGCAAGTGTCAAGGACTTCGCGGCCCGACTTGCCGGGTCAGGCATCGCGGCGGGGGCAATTGC
CAGCCGTTTCATTGGCAACCTTTGTGGGTTTGACAACTCCATCGGCTTTGACATGGGCGGTACAAGCACCGACGTCTCGC
TGGTCTACGAGGGCAAGTCACGGGTCACGAAAGACTGGTACATCGAATACGGCTACCCGATCCGGTTCCCGTCCATCGAA
GTGCTGACCATCGGTGCAGGTGGCGGGTCGCTGGCATGGAAAGACGAAGGCGGTTCGCTGCGCAACGGTCCGCAGTCTGC
GGGCGCGTTCCCGGGGCCGGCGTGCTACAAGAACGGCAATGAGGTCGCGACGAACACGGACGCGAATGTTGTTCTGGGCC
GCCTTGGCACCTCACTGGCAGGTGGCAAGATTACCCTTGATCCCGCTCTGGCCGAAGCCTCGGTCAGAGAGACCGTGGCA
GAGCCGTTCGGCATGGAACTGCACGAAGCCGCAGAAGCCATTGTTGCGGTTGCCAACGCAAATATGGCCAACGCCGTGCG
TTTGCTGTCCATCAGCCGGGGCTATGACCCGCGCGACTTCGCACTTGTGGCCTTCGGCGGTGCGGGCGCCTTGCACGGCG
CGGCGATCGCCAGGGAACTGTCGATTCCGACTGTCATTATCCCGCCAAATCCGGGCGTGACTTCGGCTTTGGGCTGCTTG
CTCGTGGACATCCAGCACGATTTCTCCGACAGCTTCATGGCCGCAGCGGCAGACACCAAGCCAGAGGATGTGGAGGCTGC
TTTTGAACGTCTGGAAGCCATGGCCGCAGAGCGACTGAAGCATGAAGGCGTGGCACCCAAGGACATTGTCATGCAGCGCA
CCGTCGAGATGATGTATCAGGGTCAGTGGCGTGCTCTGGCAGTTGCCGCCCCTTCCAAGGTCACGGACATCGACTCGCTG
ATTGATGCTTTCCACAACGAGCATCAGCGGGAATTCAACTTCCGTCGTGATGATGCGCCGGTGTCGATTTTCCGGGTGGG
GCTGACCGCAACGGGCATGGTGCCCAAGGCGGAGCTGCAATCCCACGAGGTCAAGAAAAACACACCAACAACCGACAATA
CGCGCGACGTCTGGTTTGACGGCAAGGCCCACACCGCGATGATTTTCGAGCGTGATGATCTGACCGCCGGGGCAACATTC
GACGGTCCCGCGATTGTCGAGCAGTTTGACTCAACCACCGTGATTCCGCCGAACACGACTGCTGAAGTCGACAAATACAT
GAACATTCTCATCCGAGTTCAGGAGTAA

Upstream 100 bases:

>100_bases
TGCTTCACCGTAAACCAACCTTAACAAACGGAAACCTCTCATTGGGTCGGCCTGCGCCGACACCATTGTGATGCCTTGTT
GTCTTTTGAAGGATGAAAGA

Downstream 100 bases:

>100_bases
AATCATGAGTGATTCAAAAGCCCTAGACCCCGTCACGTTTGAAGTTCTCAAGAACTCATTCATCACCTCGGTCGACCAGA
TGGCCGAGCAGATGTTGCGT

Product: hydantoin utilization protein A, putative

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MKNTRVAVDVGGTFTDVCIMDETTGAIRIEKTSSTPDDPMVAILNGIDQGGIDLSEVSMFSHGTTVATNALITRNLARSA
MICTEGFRDVVEIRRANKEDLWDTYKDVAKPYIPRRDRLTVRECVDANGTVLEKLDEEEALRIANILKKRKVASVAVCFM
NSYTNGANEERMRDILLSVMPDVPVSISSQVLPEIFEHERFSTTMANAVVSPSVVDYVERLEGKLSDGGYERDLLLLHTG
GGVMTPASVKDFAARLAGSGIAAGAIASRFIGNLCGFDNSIGFDMGGTSTDVSLVYEGKSRVTKDWYIEYGYPIRFPSIE
VLTIGAGGGSLAWKDEGGSLRNGPQSAGAFPGPACYKNGNEVATNTDANVVLGRLGTSLAGGKITLDPALAEASVRETVA
EPFGMELHEAAEAIVAVANANMANAVRLLSISRGYDPRDFALVAFGGAGALHGAAIARELSIPTVIIPPNPGVTSALGCL
LVDIQHDFSDSFMAAAADTKPEDVEAAFERLEAMAAERLKHEGVAPKDIVMQRTVEMMYQGQWRALAVAAPSKVTDIDSL
IDAFHNEHQREFNFRRDDAPVSIFRVGLTATGMVPKAELQSHEVKKNTPTTDNTRDVWFDGKAHTAMIFERDDLTAGATF
DGPAIVEQFDSTTVIPPNTTAEVDKYMNILIRVQE

Sequences:

>Translated_675_residues
MKNTRVAVDVGGTFTDVCIMDETTGAIRIEKTSSTPDDPMVAILNGIDQGGIDLSEVSMFSHGTTVATNALITRNLARSA
MICTEGFRDVVEIRRANKEDLWDTYKDVAKPYIPRRDRLTVRECVDANGTVLEKLDEEEALRIANILKKRKVASVAVCFM
NSYTNGANEERMRDILLSVMPDVPVSISSQVLPEIFEHERFSTTMANAVVSPSVVDYVERLEGKLSDGGYERDLLLLHTG
GGVMTPASVKDFAARLAGSGIAAGAIASRFIGNLCGFDNSIGFDMGGTSTDVSLVYEGKSRVTKDWYIEYGYPIRFPSIE
VLTIGAGGGSLAWKDEGGSLRNGPQSAGAFPGPACYKNGNEVATNTDANVVLGRLGTSLAGGKITLDPALAEASVRETVA
EPFGMELHEAAEAIVAVANANMANAVRLLSISRGYDPRDFALVAFGGAGALHGAAIARELSIPTVIIPPNPGVTSALGCL
LVDIQHDFSDSFMAAAADTKPEDVEAAFERLEAMAAERLKHEGVAPKDIVMQRTVEMMYQGQWRALAVAAPSKVTDIDSL
IDAFHNEHQREFNFRRDDAPVSIFRVGLTATGMVPKAELQSHEVKKNTPTTDNTRDVWFDGKAHTAMIFERDDLTAGATF
DGPAIVEQFDSTTVIPPNTTAEVDKYMNILIRVQE
>Mature_675_residues
MKNTRVAVDVGGTFTDVCIMDETTGAIRIEKTSSTPDDPMVAILNGIDQGGIDLSEVSMFSHGTTVATNALITRNLARSA
MICTEGFRDVVEIRRANKEDLWDTYKDVAKPYIPRRDRLTVRECVDANGTVLEKLDEEEALRIANILKKRKVASVAVCFM
NSYTNGANEERMRDILLSVMPDVPVSISSQVLPEIFEHERFSTTMANAVVSPSVVDYVERLEGKLSDGGYERDLLLLHTG
GGVMTPASVKDFAARLAGSGIAAGAIASRFIGNLCGFDNSIGFDMGGTSTDVSLVYEGKSRVTKDWYIEYGYPIRFPSIE
VLTIGAGGGSLAWKDEGGSLRNGPQSAGAFPGPACYKNGNEVATNTDANVVLGRLGTSLAGGKITLDPALAEASVRETVA
EPFGMELHEAAEAIVAVANANMANAVRLLSISRGYDPRDFALVAFGGAGALHGAAIARELSIPTVIIPPNPGVTSALGCL
LVDIQHDFSDSFMAAAADTKPEDVEAAFERLEAMAAERLKHEGVAPKDIVMQRTVEMMYQGQWRALAVAAPSKVTDIDSL
IDAFHNEHQREFNFRRDDAPVSIFRVGLTATGMVPKAELQSHEVKKNTPTTDNTRDVWFDGKAHTAMIFERDDLTAGATF
DGPAIVEQFDSTTVIPPNTTAEVDKYMNILIRVQE

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=725, Percent_Identity=30.3448275862069, Blast_Score=220, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI133901900, Length=720, Percent_Identity=26.8055555555556, Blast_Score=186, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322634, Length=745, Percent_Identity=29.261744966443, Blast_Score=224, Evalue=3e-59,
Organism=Drosophila melanogaster, GI45550492, Length=737, Percent_Identity=28.9009497964722, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 72757; Mature: 72757

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTRVAVDVGGTFTDVCIMDETTGAIRIEKTSSTPDDPMVAILNGIDQGGIDLSEVSMF
CCCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHH
SHGTTVATNALITRNLARSAMICTEGFRDVVEIRRANKEDLWDTYKDVAKPYIPRRDRLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCH
VRECVDANGTVLEKLDEEEALRIANILKKRKVASVAVCFMNSYTNGANEERMRDILLSVM
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
PDVPVSISSQVLPEIFEHERFSTTMANAVVSPSVVDYVERLEGKLSDGGYERDLLLLHTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECC
GGVMTPASVKDFAARLAGSGIAAGAIASRFIGNLCGFDNSIGFDMGGTSTDVSLVYEGKS
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC
RVTKDWYIEYGYPIRFPSIEVLTIGAGGGSLAWKDEGGSLRNGPQSAGAFPGPACYKNGN
CCCEEEEEEECCEEECCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCC
EVATNTDANVVLGRLGTSLAGGKITLDPALAEASVRETVAEPFGMELHEAAEAIVAVANA
CEECCCCCCEEEEHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
NMANAVRLLSISRGYDPRDFALVAFGGAGALHGAAIARELSIPTVIIPPNPGVTSALGCL
CHHHHEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHE
LVDIQHDFSDSFMAAAADTKPEDVEAAFERLEAMAAERLKHEGVAPKDIVMQRTVEMMYQ
EEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GQWRALAVAAPSKVTDIDSLIDAFHNEHQREFNFRRDDAPVSIFRVGLTATGMVPKAELQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEECCCCCHHHHH
SHEVKKNTPTTDNTRDVWFDGKAHTAMIFERDDLTAGATFDGPAIVEQFDSTTVIPPNTT
HCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCEEECCCCH
AEVDKYMNILIRVQE
HHHHHHEEEEEEECC
>Mature Secondary Structure
MKNTRVAVDVGGTFTDVCIMDETTGAIRIEKTSSTPDDPMVAILNGIDQGGIDLSEVSMF
CCCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHH
SHGTTVATNALITRNLARSAMICTEGFRDVVEIRRANKEDLWDTYKDVAKPYIPRRDRLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCH
VRECVDANGTVLEKLDEEEALRIANILKKRKVASVAVCFMNSYTNGANEERMRDILLSVM
HHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
PDVPVSISSQVLPEIFEHERFSTTMANAVVSPSVVDYVERLEGKLSDGGYERDLLLLHTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECC
GGVMTPASVKDFAARLAGSGIAAGAIASRFIGNLCGFDNSIGFDMGGTSTDVSLVYEGKS
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC
RVTKDWYIEYGYPIRFPSIEVLTIGAGGGSLAWKDEGGSLRNGPQSAGAFPGPACYKNGN
CCCEEEEEEECCEEECCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCC
EVATNTDANVVLGRLGTSLAGGKITLDPALAEASVRETVAEPFGMELHEAAEAIVAVANA
CEECCCCCCEEEEHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
NMANAVRLLSISRGYDPRDFALVAFGGAGALHGAAIARELSIPTVIIPPNPGVTSALGCL
CHHHHEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHE
LVDIQHDFSDSFMAAAADTKPEDVEAAFERLEAMAAERLKHEGVAPKDIVMQRTVEMMYQ
EEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GQWRALAVAAPSKVTDIDSLIDAFHNEHQREFNFRRDDAPVSIFRVGLTATGMVPKAELQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEECCCCCHHHHH
SHEVKKNTPTTDNTRDVWFDGKAHTAMIFERDDLTAGATFDGPAIVEQFDSTTVIPPNTT
HCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCEEECCCCH
AEVDKYMNILIRVQE
HHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]