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The map label for this gene is xerD [H]

Identifier: 110680280

GI number: 110680280

Start: 2964604

End: 2965575

Strand: Direct

Name: xerD [H]

Synonym: RD1_3091

Alternate gene names: 110680280

Gene position: 2964604-2965575 (Clockwise)

Preceding gene: 110680279

Following gene: 110680281

Centisome position: 71.73

GC content: 63.17

Gene sequence:

>972_bases
ATGGCGGCGCACGGTACGTGGATTTCCGCTTTCCTTGAGGCGCAGGCTGCGGAACTTGGCGCCGCGCGCAACACGCTTTT
GGCCTATGGTCGTGACCTCAAGGATTTCGAGGGCTACCTGCATCACCGCACTCTGGACTTTGCCACCGCGACGCAGGGCG
ATGTCGAGGCCTATCTGATCGCCTGTGACGCGCAGGGGCTTTCAAAGGCGACGCGGGCGCGCAGGCTTTCGGCGGTCAAG
CAGCTTTATCGTTTTGCCTTCGAGGAAGGCTGGCGCAGCGACAACCCGGCCTTGCAGATCACAGGCCCGGGACGCGACCG
CAAACTGCCCAAAACCCTGTCCGAAGCAGAAGTGGACAGGCTGCTTGAGGCCGCCCGCACCTCGGGGCGCAACGCGGCAG
ACCGGGCGCGCAACACCTGCCTGATGGAACTGCTCTATGCGACTGGCATGCGCGTCAGCGAGTTGGTCAGCCTGCCCGTC
TCTGCGGCGCGGGGCGATCCGCGCATGTTGTTGATCCGCGGCAAGGGTGGCAAGGAGCGGATGGTGCCCCTGTCGCCCCC
TGCCCGCGATGCCACATCAGAGTGGTTGCAGCTGCGCGACGAGAAAGAGGCCCAGAAAAAGACCGAAGGGCATCCGCCCT
CCCGGTTTCTGTTCGCATCACGCGGTGTGTCCGGGCATCTGACGCGGCATCGTTTCTATCTGCTGATCAAGGAGTTGGCA
GTCAATGCGGGCGTCAGCCCGTCCAAGGTCACCCCCCACACGCTGCGTCATGCTTTCGCCACGCATCTGCTGGCAAATGG
CGCGGATTTACGCTCGATTCAGACGCTGTTGGGTCACGCGGATGTGGCCACGACAGAAATCTACACCCATGTGCTGGAGG
CCAGACTGTCCGAATTGGTGCTCACGCACCACCCGCTGGCGCAAGACGATACGCGCGCACCGGGTGACAAAACCGCGCTG
GATGGATCATAA

Upstream 100 bases:

>100_bases
TTGCCCTGACGCAGGCGCTTGCGACTTTGCGGTCGTTCGGTCTTGAGGACACGGTGCGCCGCGCCGCCCTGCAGGTCCTG
CTGCTGGACAGATACAGCTG

Downstream 100 bases:

>100_bases
CCCGTTCTCTCCGACATATCGCGCCATGAACGGGTGATCATCCCGGCGGTAGACTGTCGCAGACCCGCCCGGATGCGCAG
GCATTGCGGGCGCCTCCCTT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAAHGTWISAFLEAQAAELGAARNTLLAYGRDLKDFEGYLHHRTLDFATATQGDVEAYLIACDAQGLSKATRARRLSAVK
QLYRFAFEEGWRSDNPALQITGPGRDRKLPKTLSEAEVDRLLEAARTSGRNAADRARNTCLMELLYATGMRVSELVSLPV
SAARGDPRMLLIRGKGGKERMVPLSPPARDATSEWLQLRDEKEAQKKTEGHPPSRFLFASRGVSGHLTRHRFYLLIKELA
VNAGVSPSKVTPHTLRHAFATHLLANGADLRSIQTLLGHADVATTEIYTHVLEARLSELVLTHHPLAQDDTRAPGDKTAL
DGS

Sequences:

>Translated_323_residues
MAAHGTWISAFLEAQAAELGAARNTLLAYGRDLKDFEGYLHHRTLDFATATQGDVEAYLIACDAQGLSKATRARRLSAVK
QLYRFAFEEGWRSDNPALQITGPGRDRKLPKTLSEAEVDRLLEAARTSGRNAADRARNTCLMELLYATGMRVSELVSLPV
SAARGDPRMLLIRGKGGKERMVPLSPPARDATSEWLQLRDEKEAQKKTEGHPPSRFLFASRGVSGHLTRHRFYLLIKELA
VNAGVSPSKVTPHTLRHAFATHLLANGADLRSIQTLLGHADVATTEIYTHVLEARLSELVLTHHPLAQDDTRAPGDKTAL
DGS
>Mature_322_residues
AAHGTWISAFLEAQAAELGAARNTLLAYGRDLKDFEGYLHHRTLDFATATQGDVEAYLIACDAQGLSKATRARRLSAVKQ
LYRFAFEEGWRSDNPALQITGPGRDRKLPKTLSEAEVDRLLEAARTSGRNAADRARNTCLMELLYATGMRVSELVSLPVS
AARGDPRMLLIRGKGGKERMVPLSPPARDATSEWLQLRDEKEAQKKTEGHPPSRFLFASRGVSGHLTRHRFYLLIKELAV
NAGVSPSKVTPHTLRHAFATHLLANGADLRSIQTLLGHADVATTEIYTHVLEARLSELVLTHHPLAQDDTRAPGDKTALD
GS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=44.1860465116279, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1790244, Length=290, Percent_Identity=31.7241379310345, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790767, Length=185, Percent_Identity=34.5945945945946, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790768, Length=165, Percent_Identity=34.5454545454545, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35459; Mature: 35327

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHGTWISAFLEAQAAELGAARNTLLAYGRDLKDFEGYLHHRTLDFATATQGDVEAYLI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCEEEEE
ACDAQGLSKATRARRLSAVKQLYRFAFEEGWRSDNPALQITGPGRDRKLPKTLSEAEVDR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
LLEAARTSGRNAADRARNTCLMELLYATGMRVSELVSLPVSAARGDPRMLLIRGKGGKER
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCEEEEECCCCCCC
MVPLSPPARDATSEWLQLRDEKEAQKKTEGHPPSRFLFASRGVSGHLTRHRFYLLIKELA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCHHHHHHHHHHHHHH
VNAGVSPSKVTPHTLRHAFATHLLANGADLRSIQTLLGHADVATTEIYTHVLEARLSELV
HHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LTHHPLAQDDTRAPGDKTALDGS
HHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAHGTWISAFLEAQAAELGAARNTLLAYGRDLKDFEGYLHHRTLDFATATQGDVEAYLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCEEEEE
ACDAQGLSKATRARRLSAVKQLYRFAFEEGWRSDNPALQITGPGRDRKLPKTLSEAEVDR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
LLEAARTSGRNAADRARNTCLMELLYATGMRVSELVSLPVSAARGDPRMLLIRGKGGKER
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCEEEEECCCCCCC
MVPLSPPARDATSEWLQLRDEKEAQKKTEGHPPSRFLFASRGVSGHLTRHRFYLLIKELA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCHHHHHHHHHHHHHH
VNAGVSPSKVTPHTLRHAFATHLLANGADLRSIQTLLGHADVATTEIYTHVLEARLSELV
HHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LTHHPLAQDDTRAPGDKTALDGS
HHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]